Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:32 PM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Coronary Artery Disease
Interventions
Fractional Flow Reserve
Diagnostic Test
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
18 Years to 89 Years
Enrollment
1,000 participants
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Completed No phase listed Observational

FAME II-10-year Follow-Up

NCT06159231
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
CoreAalst BV
Industry
Eligibility
21 Years and older
Enrollment
888 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Stanford, California • Decatur, Georgia • Bangor, Maine
Completed Not applicable Interventional Results available

Complete Lesion Assessment With ffR and IVUS TechnologY

NCT01941030
Conditions
Peripheral Artery Disease, Critical Limb Ischemia
Interventions
Orbital Atherectomy System, Balloon Angioplasty
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Davenport, Iowa + 5 more
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Coronary Artery Disease
Interventions
ComboMap XT Guidewire, 'SPY' NIRF During CABG
Device · Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Greenville, North Carolina
Conditions
Coronary Artery Disease
Interventions
RXi System, Pressure Wire
Device
Lead sponsor
Acist Medical Systems
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
La Jolla, California • Long Beach, California • Stanford, California + 8 more
Conditions
Peripheral Arterial Disease, Fractional Flow Reserve, Hemodynamics
Interventions
Translesional Hemodynamic Measurement
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Terminated Not applicable Interventional Results available

The Computed Tomography-derived Fractional Flow Reserve STAT Trial

NCT03263806
Conditions
Heart Disease, Coronary, Chest Pain, Acute Coronary Syndrome
Interventions
CTFFR-Guided Group Management, SOC Group Management
Diagnostic Test
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Acute Myocardial Infarction, STEMI, Coronary Artery Disease, Atherosclerotic Plaque Disruption With Thrombosis of Artery
Interventions
Coronary Angiography
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Coronary Artery Disease
Interventions
FFR
Device
Lead sponsor
HeartFlow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Mobile, Alabama
Conditions
Coronary Artery Disease
Interventions
Adenosine, Contrast Media, Resting conditions
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
763 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Palo Alto, California • Oklahoma City, Oklahoma
Conditions
Coronary Artery Disease
Interventions
adenosine, regadenoson
Drug
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Jacksonville, Florida • St Louis, Missouri
Conditions
Coronary Disease, Percutaneous Coronary Intervention, Exercise Test, Myocardial Perfusion Imaging, Cardiac Catheterization
Interventions
No study intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Coronary Artery Disease
Interventions
Vessel Fractional Flow Reserve
Diagnostic Test
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Coronary Artery Stenosis
Interventions
FFR, IVUS, VH, or combination of the three
Procedure
Lead sponsor
Piedmont Healthcare
Other
Eligibility
21 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Coronary Artery Disease
Interventions
FFR Measurement with IV Adenoscan® then with Regadenoson
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Atherosclerosis, Coronary
Interventions
CCTA
Diagnostic Test
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Coronary Artery Disease, Stable Angina, Unstable Angina, Non-ST-Elevation Myocardial Infarction
Interventions
MedHub AutocathFFR
Device
Lead sponsor
Medhub Ltd.
Industry
Eligibility
23 Years and older
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Gainesville, Georgia + 1 more
Conditions
Non-obstructive Coronary Disease, Acute or Chronic Coronary Artery Disease
Interventions
Patients with intermediate coronary artery stenosis with clinically indicated FFR assessment., Microvascular assessment
Procedure
Lead sponsor
AngioInsight
Industry
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
9
States / cities
Palo Alto, California • Washington D.C., District of Columbia • Minneapolis, Minnesota + 4 more
Conditions
Angina
Interventions
Ranolazine, Sugar pill
Drug
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Coronary Artery Disease
Interventions
FFR/CFR and IVUS
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Cincinnati, Ohio
Conditions
Coronary Artery Stenoses, Aortic Stenosis
Interventions
Volcano iFR/FFR Verrata Plus coronary pressure/flow wire
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 110 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Coronary Artery Disease
Interventions
Invasive Cardiac Catheterization (ICA), Coronary Computed Tomographic Angiogram (CCTA), Dynamic Cardiac Positron Emission Tomography (dPET)
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia • Roslyn, New York
Conditions
Coronary Artery Disease
Interventions
Stenting plus OMT, OMT, Standard of care
Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
21 Years and older
Enrollment
1,170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
6
States / cities
Palo Alto, California • Stanford, California • Atlanta, Georgia + 3 more