Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 6, 2026, 9:28 AM EDT

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Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.
Conditions
Coronary Artery Disease
Interventions
ComboMap XT Guidewire, 'SPY' NIRF During CABG
Device · Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Greenville, North Carolina
Completed Not applicable Interventional Results available

Side Branch FFR After Provisional Stenting

NCT03115580
Conditions
Coronary Artery Disease
Interventions
Rotational atherectomy, Cutting Balloon Angioplasty
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Terminated Not applicable Interventional Results available

The Computed Tomography-derived Fractional Flow Reserve STAT Trial

NCT03263806
Conditions
Heart Disease, Coronary, Chest Pain, Acute Coronary Syndrome
Interventions
CTFFR-Guided Group Management, SOC Group Management
Diagnostic Test
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Completed No phase listed Observational Results available

PRESSUREwire Study

NCT02935088
Conditions
Coronary Artery Disease, Acute Coronary Syndrome
Interventions
Fractional Flow Reserve
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Huntsville, Alabama • Orlando, Florida • Decatur, Georgia + 1 more
Conditions
Coronary Artery Disease
Interventions
FFR
Device
Lead sponsor
HeartFlow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Mobile, Alabama
Conditions
Coronary Artery Disease
Interventions
Adenosine, Contrast Media, Resting conditions
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
763 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Palo Alto, California • Oklahoma City, Oklahoma
Conditions
Coronary Artery Disease
Interventions
Invasive Cardiac Catheterization (ICA), Coronary Computed Tomographic Angiogram (CCTA), Dynamic Cardiac Positron Emission Tomography (dPET)
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia • Roslyn, New York
Conditions
Coronary Artery Disease, Microvascular Coronary Artery Disease
Interventions
Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance
Diagnostic Test
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
2,322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Coronary Artery Disease
Interventions
FFR-guided PCI, CABG
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Stanford, California
Conditions
Coronary Artery Disease
Interventions
RXi System, Pressure Wire
Device
Lead sponsor
Acist Medical Systems
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
La Jolla, California • Long Beach, California • Stanford, California + 8 more
Completed No phase listed Observational Results available

Observational Study of OCT in a Patients Undergoing FFR

NCT01663896
Conditions
Coronary Artery Disease
Interventions
OCT stent guidance
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
15
States / cities
Birmingham, Alabama • La Jolla, California • Orlando, Florida + 12 more
Terminated Not applicable Interventional Results available

Simultaneous Assessment of FFR and SPECT

NCT02749045
Conditions
Coronary Artery Disease
Interventions
SPECT imaging
Radiation
Lead sponsor
Prem Soman
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Coronary Artery Disease
Interventions
Vessel Fractional Flow Reserve
Diagnostic Test
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Angina
Interventions
Ranolazine, Sugar pill
Drug
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Completed No phase listed Observational

FAME II-10-year Follow-Up

NCT06159231
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
CoreAalst BV
Industry
Eligibility
21 Years and older
Enrollment
888 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Stanford, California • Decatur, Georgia • Bangor, Maine
Conditions
Coronary Arteriosclerosis
Interventions
Fractional flow reserve, Angio-guided PCI
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,005 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Stanford, California
Conditions
Coronary Artery Disease
Interventions
FFR Measurement with IV Adenoscan® then with Regadenoson
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Non-obstructive Coronary Disease, Acute or Chronic Coronary Artery Disease
Interventions
Patients with intermediate coronary artery stenosis with clinically indicated FFR assessment., Microvascular assessment
Procedure
Lead sponsor
AngioInsight
Industry
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
9
States / cities
Palo Alto, California • Washington D.C., District of Columbia • Minneapolis, Minnesota + 4 more
Conditions
Acute Myocardial Infarction, STEMI, Coronary Artery Disease, Atherosclerotic Plaque Disruption With Thrombosis of Artery
Interventions
Coronary Angiography
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan