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ClinicalTrials.gov public records Last synced Jun 25, 2026, 7:31 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Transitional Care, Frail Elderly, Home Health Care
Interventions
Transition Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Muscle Weakness
Interventions
10 home-based functional services sessions over 4 months.
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Exercise Poles on Older Adults During Exercise Walking

NCT00037167
Conditions
Movement Disorders, Aging
Interventions
Exercise poles
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
65 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Muncie, Indiana
Conditions
Chronic Illness, Cognitive Impairment
Interventions
MD2 machine and nurse care coordination, Medplanner and Nurse Care Coordination
Other
Lead sponsor
Arizona State University
Other
Eligibility
60 Years and older
Enrollment
414 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Heart Failure
Interventions
Rapamune
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Frailty
Interventions
Enhanced Engagement, Standard Engagement
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
60 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Completed Phase 2 Interventional Results available

Ghrelin Plus Strength Training in Frail Elderly Study

NCT01898611
Conditions
Frailty Syndrome
Interventions
Ghrelin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
70 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Geriatric Anorexia Study 2.0

NCT05211973
Conditions
Healthy, Frailty
Interventions
Wrist Actigraphy Device, Smart Body Weight Scale, Chair Scale, Handheld Body Fat Percentage Device, Bioelectric Impedance Analysis Scale
Device
Lead sponsor
Boston University
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Results available

Educational-Medical-Behavioral Treatment of Fecal Incontinence

NCT01717456
Conditions
Fecal Incontinence
Interventions
Education, Fiber supplements, Laxatives or anti-diarrheals, Pelvic floor muscle exercises, Tips on how to prevent fecal incontinence, Daily diary, Protective pads or garments
Other · Dietary Supplement · Drug + 1 more
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed No phase listed Observational Accepts healthy volunteers Results available

Preoperative Cognitive Screening in Older Spinal Surgical Patients

NCT02922634
Conditions
Cognitive Impairment, Frail Elderly Syndrome
Interventions
Mini Cog
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
70 Years and older
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Head and Neck Cancer, Head and Neck Neoplasms
Interventions
TNFerade biologic
Drug
Lead sponsor
GenVec
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Elderly, Frail, Accidental Falls, Hospitals
Interventions
Room configuration
Other
Lead sponsor
University of Utah
Other
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Withdrawn Not applicable Interventional Accepts healthy volunteers

Training the Brain with a Robotic Device for Balance Recovery

NCT02765425
Conditions
Fall Risk, Healthy Elderly
Interventions
AMES
Device
Lead sponsor
University of Arkansas
Other
Eligibility
65 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Fayetteville, Arkansas
Conditions
Muscle Weakness
Interventions
Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years to 110 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Transplant-Related Disorder, Frail Elderly Syndrome, Sarcopenia, Lung Graft Dysfunction, Mobility Limitation
Interventions
Ambulation
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Insomnia Disorder
Interventions
education and coaching on developing healthy nighttime sleep and daytime activity behaviors
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Frail Elderly Syndrome
Interventions
Fisetin, Placebo oral capsule
Dietary Supplement · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Frail Elderly, Homebound Persons
Interventions
Progressive High Intensity Therapy (PHIT), Usual Care (UC)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 99 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Congestive Heart Failure, Cancer, Chronic Obstructive Pulmonary Disease, Cerebrovascular Accident, Frail Elderly Syndrome, Cardiovascular Diseases
Interventions
Serious Illness Care Program (SICP)
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
1,120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Aurora, Colorado • Iowa City, Iowa • Durham, North Carolina + 2 more
Completed Not applicable Interventional Results available

Zoledronic Acid for Osteoporosis in the Elderly

NCT00558012
Conditions
Osteoporosis, Bone Loss, Fragility Fractures
Interventions
Intravenous zoledronic acid, Vitamin D 800 IU/daily, Calcium 1200 mg/daily
Drug · Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Frailty and Dysphagia in Older Adults

NCT04975815
Conditions
Dysphagia, Frailty
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
65 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Delirium, Age-Related Cognitive Decline, Frail Elderly, Hospital Acquired Pressure Ulcer, Drug-Related Side Effects and Adverse Reactions
Interventions
Acute Care of Elders focused geriatric care
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Vitamin D in Vulnerable Adults (VIVA-VA)

NCT01170273
Conditions
Frail Elderly, Vitamin d Deficiency
Interventions
vitamin D, placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 95 Years · Male only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Miami, Florida