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Showing 1–24 of 416 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Functional Outcomes Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly

NCT01899586
View directory record Official record
Conditions
Elderly, Sedentary
Interventions
Regional Specific Training Stimulus (RSTS), Aerobic Exercise Regimen (AE)
Other
Lead sponsor
Duke University
Other
Eligibility
70 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Sep 7, 2026, 10:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pilot Study Evaluating Functional and Wellness Outcomes of the Shepherd CAN DO MS Program

NCT03954717
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Shepherd CAN DO Program
Behavioral
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

NCT05723679
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction, Obesity
Interventions
HeO2 gas mixture, Room air gas mixture
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years to 90 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Completed No phase listed Observational Results available

Cognition and Psychotherapy in PTSD

NCT03641924
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Sep 7, 2026, 10:58 PM EDT
Terminated No phase listed Observational

Functional Image and Molecular Markers to Predict Treatment Outcomes in Lung Cancer

NCT02117440
View directory record Official record
Conditions
Lung Neoplasms
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting No phase listed Observational

MRI/Ultrasound Fusion Guided Prostate Cryotherapy

NCT02381990
View directory record Official record
Conditions
Neoplasms Prostate, Cancer of the Prostate
Interventions
FUSE IMAGE MRI GUIDED PROSTATE CRYOTHERAPY
Procedure
Lead sponsor
Urological Research Network, LLC
Other
Eligibility
55 Years and older · Male only
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2033
U.S. locations
1
States / cities
Miami Lakes, Florida
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Sep 7, 2026, 10:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Mindfulness on Pain After Total Knee Arthroplasty

NCT06118073
View directory record Official record
Conditions
Total Knee Replacement, Post Operative Pain, Opioid Use
Interventions
Headspace, Total Knee Replacement
Other · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting Phase 4 Interventional

Randomized Trial of SGLT2i in Heart Transplant Recipients

NCT06625073
View directory record Official record
Conditions
Heart Transplant, Cardiovascular Disease, Kidney Disease
Interventions
Empagliflozin, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
6
States / cities
Palo Alto, California • Nashville, Tennessee • Houston, Texas + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional Results available

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

NCT02588027
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 7, 2026, 10:58 PM EDT
Withdrawn Phase 4 Interventional

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

NCT01179100
View directory record Official record
Conditions
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions
Lidocaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional

Electronic Monitoring Device of Patient-Reported Outcomes and Function in Improving Patient-Centered Care in Patients With Gastrointestinal Cancer Undergoing Surgery

NCT02511821
View directory record Official record
Conditions
Stage I Adult Liver Cancer, Stage I Colorectal Cancer, Stage IA Gastric Cancer, Stage IA Pancreatic Cancer, Stage IB Gastric Cancer, Stage IB Pancreatic Cancer, Stage II Adult Liver Cancer, Stage IIA Colorectal Cancer, Stage IIA Gastric Cancer, Stage IIA Pancreatic Cancer, Stage IIB Colorectal Cancer, Stage IIB Gastric Cancer, Stage IIB Pancreatic Cancer, Stage IIC Colorectal Cancer, Stage III Pancreatic Cancer, Stage IIIA Adult Liver Cancer, Stage IIIA Colorectal Cancer, Stage IIIA Gastric Cancer, Stage IIIB Adult Liver Cancer, Stage IIIB Colorectal Cancer, Stage IIIB Gastric Cancer, Stage IIIC Adult Liver Cancer, Stage IIIC Colorectal Cancer, Stage IIIC Gastric Cancer, Stage IV Gastric Cancer, Stage IVA Colorectal Cancer, Stage IVA Liver Cancer, Stage IVA Pancreatic Cancer, Stage IVB Colorectal Cancer, Stage IVB Liver Cancer, Stage IVB Pancreatic Cancer
Interventions
Computer-Assisted Intervention, Vivofit watch, Quality-of-Life Assessment, Questionnaire Administration
Other · Device
Lead sponsor
City of Hope Medical Center
Other
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional Results available

Total Knee Arthroplasty: Functional and Clinical Outcomes

NCT01811563
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Zimmer, Stryker
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Phase 3 Interventional

Study to Evaluate the Safety of Twice Daily Oral Carvedilol

NCT00129363
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Carvedilol
Drug
Lead sponsor
Shaddy, Robert, M.D.
Individual
Eligibility
1 Day to 17 Years
Enrollment
75 participants
Timeline
2002 – 2006
U.S. locations
17
States / cities
Los Angeles, California • Palo Alto, California • Denver, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2008 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting Phase 2Phase 3 Interventional

CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients

NCT03769298
View directory record Official record
Conditions
Kidney Pancreas Transplantation
Interventions
Envarsus XR
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Terminated Not applicable Interventional

Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts

NCT02484937
View directory record Official record
Conditions
Back Pain, Chronic Pain, Pain, Intractable
Interventions
Group 2 (PCP Treatment), Group 1 (PMS Treatment)
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 7, 2026, 10:58 PM EDT
Completed No phase listed Observational

Short-term Clinical Deterioration After Acute Pulmonary Embolism

NCT03915925
View directory record Official record
Conditions
Pulmonary Embolism
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
935 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
San Diego, California • Newark, Delaware • Orlando, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury

NCT03617991
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Exercise Group
Other
Lead sponsor
Johanna M. Hoch
Other
Eligibility
18 Years to 35 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Sep 7, 2026, 10:58 PM EDT
Not listed No phase listed Observational

Outcomes of Functional Substrate Mapping of Ventricular Tachycardia

NCT05708131
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Not listed
Lead sponsor
Mid and South Essex NHS Foundation Trust
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional

Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth

NCT04385901
View directory record Official record
Conditions
SARS-CoV 2, SARS Pneumonia
Interventions
Therapy Intervention
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 7, 2021 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional Results available

Comprehensive Post-Acute Stroke Services

NCT02588664
View directory record Official record
Conditions
Stroke, Transient Ischemic Attack
Interventions
COMPASS Intervention
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
6,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
40
States / cities
Albemarle, North Carolina • Asheville, North Carolina • Chapel Hill, North Carolina + 32 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional

Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

NCT02754544
View directory record Official record
Conditions
Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain, Recurrent Brain Neoplasm
Interventions
Direct Electrocortical Stimulation, Electrocorticography
Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting Phase 2Phase 3 Interventional

Study of Cannabidiol in Sanfilippo Syndrome

NCT06333041
View directory record Official record
Conditions
Sanfilippo Syndrome, Mucopolysaccharidosis III
Interventions
Epidiolex, Placebo
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
4 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Completed Not applicable Interventional

Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)

NCT06601322
View directory record Official record
Conditions
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Interventions
Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 7, 2026, 10:58 PM EDT
Recruiting No phase listed Observational

Phenotypic Classification of FMR With CMR

NCT05965258
View directory record Official record
Conditions
Nonischemic Congestive Cardiomyopathy, Functional Mitral Regurgitation, Ischemic Cardiomyopathy
Interventions
Cardiac magnetic resonance (CMR)
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
360 participants
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 7, 2026, 10:58 PM EDT