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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gambling Disorder Clear all
Completed Not applicable Interventional

A Pilot SMART Design for Pathological Gamblers

NCT00685724
View directory record Official record
Conditions
Pathological Gambling
Interventions
Motivational Enhancement Therapy (MET), Cognitive-Behavioral Therapy (CBT)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jul 21, 2026, 11:10 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)

NCT00211822
View directory record Official record
Conditions
Pathological Gambling, Obsessive Compulsive Disorder
Interventions
fMRI
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Jul 21, 2026, 11:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impulsivity in Pathological Gambling

NCT00580567
View directory record Official record
Conditions
Pathological Gambling
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling

NCT01529047
View directory record Official record
Conditions
Gambling, Alcohol Consumption, Cannabis
Interventions
Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
17 Years to 24 Years
Enrollment
361 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Evaluation of a Brief Surf the Urge Intervention

NCT02771886
View directory record Official record
Conditions
Substance Use, Deliberate Self-harm, Trichotillomania, Aggression, Stealing, Eating Pathology, Gambling
Interventions
Surf the Urge
Behavioral
Lead sponsor
Kimberly N Schubert
Other
Eligibility
14 Years to 24 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Cognitive-Motivational Behavior Therapy for Pathological Gamblers

NCT01135264
View directory record Official record
Conditions
Pathological Gambling
Interventions
CBT, CMBT
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Jul 21, 2026, 11:10 AM EDT
Not listed No phase listed Observational

Validation of Kaihani Score for Gambling Addiction

NCT04648007
View directory record Official record
Conditions
Gambling Addiction
Interventions
Kaihani Score
Diagnostic Test
Lead sponsor
Therapeutic Solutions International
Industry
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Oceanside, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Jul 21, 2026, 11:10 AM EDT
Withdrawn Not applicable Interventional

Don't Go There: A Geospatial mHealth App for Gambling Disorder

NCT04158037
View directory record Official record
Conditions
Gambling Disorder
Interventions
mHealth App
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Drug Treatment for Pathologic Gambling Disorder

NCT00053677
View directory record Official record
Conditions
Gambling
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 4 Interventional Results available

Naltrexone for Impulse Control Disorders in Parkinson's Disease

NCT01052831
View directory record Official record
Conditions
Impulse Control Disorder, Parkinson Disease
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 3 Interventional

Safety and Efficacy Trial of Olanzapine in Outpatients With Pathological Gambling

NCT00438776
View directory record Official record
Conditions
Pathological Gambling
Interventions
olanzapine, sugar pill
Drug
Lead sponsor
Lindner Center of HOPE
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2011 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling

NCT00273702
View directory record Official record
Conditions
Pathological Gambling
Interventions
N-Acetyl Cysteine
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 29, 2007 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 2 Interventional Results available

Milk Thistle in Pathological Gambling

NCT02337634
View directory record Official record
Conditions
Pathological Gambling, Gambling Disorder
Interventions
Placebo, Milk Thistle
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 11:10 AM EDT
Not yet recruiting Not applicable Interventional

Contingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder

NCT07016100
View directory record Official record
Conditions
Gambling Disorder, Gambling Problem
Interventions
Contingency management, Cognitive behavioral therapy/ treatment as usual
Behavioral
Lead sponsor
East Tennessee State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Pathological Gambling

NCT00337753
View directory record Official record
Conditions
Pathological Gambling
Interventions
Cognitive Behavioral Therapy, Wait-list
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 4, 2010 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 2 Interventional Results available

Memantine Treatment Study of Pathological Gambling

NCT00585169
View directory record Official record
Conditions
Pathological Gambling
Interventions
Memantine Hydrochloride
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 7, 2013 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Online Coping Skills Counseling for Problem Gambling and Trauma

NCT03145792
View directory record Official record
Conditions
Gambling Disorder, Trauma, Psychological, Problem Gambling, Posttraumatic Stress Disorder
Interventions
Seeking Safety, CBT for Pathological Gambling
Behavioral
Lead sponsor
University of Windsor
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Newton Center, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Jul 21, 2026, 11:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detecting a Reward Signal in the Motor Cortex

NCT00422071
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 21, 2026, 11:10 AM EDT
Completed No phase listed Observational

Motor Cortex Reward Signaling in Parkinson Disease

NCT00558766
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
45 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 2 Interventional Results available

Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble

NCT01215357
View directory record Official record
Conditions
Pathological Gambling
Interventions
Ecopipam
Drug
Lead sponsor
Emalex Biosciences Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Los Angeles, California • New Haven, Connecticut • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SBIRT Intervention for Gambling Behaviors

NCT03287583
View directory record Official record
Conditions
Gambling Disorder
Interventions
SBIRT for Gambing, Enhanced Control
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 90 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Gambling and Brief Interventions

NCT00183599
View directory record Official record
Conditions
Gambling
Interventions
5 Minutes of Simple Advice, Motivational Enhancement Therapy (MET), Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2007
U.S. locations
6
States / cities
Bridgeport, Connecticut • Farmington, Connecticut • Hartford, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Phase 2 Interventional Results available

Tolcapone Treatment of Pathological Gambling

NCT00927563
View directory record Official record
Conditions
Pathological Gambling
Interventions
Tolcapone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Jul 21, 2026, 11:10 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Treatments for Pathological Gambling

NCT00618462
View directory record Official record
Conditions
Gambling
Interventions
Cognitive behavioral therapy (CBT), Contingency management (CM), Psychoeducation therapy, Case management, Gamblers Anonymous (GA)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jul 21, 2026, 11:10 AM EDT