Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 25, 2026, 11:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Gingival Diseases Clear all
Completed Not applicable Interventional

Effect of Gum Arabic on Gastrointestinal Transit and Permeability

NCT03742076
View directory record Official record
Conditions
Diverticulitis
Interventions
High-dose prebiotic, Low-dose prebiotic, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ToothWave Plaque and Gingivitis Study

NCT03885323
View directory record Official record
Conditions
Gingivitis, Plaque, Calculus, Dental
Interventions
RF utilizing powered toothbrush, Control placebo with no RF
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional

Impact of Brief Motivational Interviewing on Periodontal Clinical Outcomes: a 3-year Post-trial Follow-up

NCT05336396
View directory record Official record
Conditions
Periodontal Diseases, Plaque Score, Bleeding on Probing, Gingival Index
Interventions
BMI
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jun 25, 2026, 11:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Evaluate Associations Between Gingivitis and Pregnancy Outcomes

NCT00641901
View directory record Official record
Conditions
Pregnancy-associated Gingivitis
Interventions
counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Jun 25, 2026, 11:56 PM EDT
Terminated Phase 4 Interventional Results available

e-Cigarettes Versus NRT Gum for Smoking Cessation

NCT01925781
View directory record Official record
Conditions
Nicotine Addiction, Smoking Cessation
Interventions
Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer
Drug · Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate Bone and Gum Dimension Changes Around Dental Implants Placed in Different Positions in Bone.

NCT01759537
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Ankylos dental endosseous implants-Sub-crestal, Ankylos dental endosseous implants-Epi-crestal
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Jun 25, 2026, 11:56 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Assessing Gingivitis and Plaque From a Marketed Toothpaste

NCT07158112
View directory record Official record
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Whitter, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jun 25, 2026, 11:56 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Microderm for Root Coverage Procedures

NCT07203326
View directory record Official record
Conditions
Connective Tissue Graft, Gum Recession
Interventions
Alloderm, MicroDerm
Biological
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Peri-implant Mucositis in Humans

NCT01941797
View directory record Official record
Conditions
Peri-implant Mucositis, Gingivitis
Interventions
interruption of oral hygiene
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Jun 25, 2026, 11:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients

NCT07164989
View directory record Official record
Conditions
Gingivitis, DMFT Index, Dental Plaque Index, Oral Hygiene Education Methods, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment, Motivational Interview, OHI
Interventions
Motivational Interviewing-Based Counseling, Standard Oral Health Education
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 19 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Phase 2 Interventional

Pilot Efficacy Study to Treat Gingivitis

NCT00391547
View directory record Official record
Conditions
Gingival Diseases
Interventions
Frio Oral Rinse
Drug
Lead sponsor
Biomedical Development Corporation
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 21, 2007 · Synced Jun 25, 2026, 11:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Follow-Up Survey of Oral Hygiene and Health Outcomes for Women Previously Enrolled in "OHMOM"

NCT02922010
View directory record Official record
Conditions
Gingivitis
Interventions
Not listed
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Jun 25, 2026, 11:56 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction

NCT02598778
View directory record Official record
Conditions
Dental Caries
Interventions
Chlorhexidine gluconate (0.12%), Sodium Fluoride (0.05%), Paraffin wax chewing gum (sugar-free), Deionized water
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2022 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Early Phase 1 Interventional

Phosphate Binding of Chitosan Chewing Gum in Patients With Chronic Kidney Disease (CKD)

NCT01341691
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
chewing gum
Other
Lead sponsor
Denver Nephrologists, P.C.
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 25, 2011 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional

Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery

NCT01559662
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Sugared Chewing Gum (Juicy Fruit)
Dietary Supplement
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2012 · Synced Jun 25, 2026, 11:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

NCT05961566
View directory record Official record
Conditions
Recession, Gingival
Interventions
Use of collagen matrix after subepithelial connective tissue graft harvest
Device
Lead sponsor
Hailey Bivens
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Jun 25, 2026, 11:56 PM EDT
Active, not recruiting Phase 2 Interventional

Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant

NCT05579639
View directory record Official record
Conditions
Allogeneic Stem Cell Transplantation
Interventions
Xylitol, Placebo
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
4 Months to 25 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Aurora, Colorado • Boston, Massachusetts • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional Results available

A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentis™) on Gingivitis

NCT01811316
View directory record Official record
Conditions
Gingivitis
Interventions
Probiotics
Other
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Jun 25, 2026, 11:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

NCT03657589
View directory record Official record
Conditions
Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluate Inflammation Caused by Gingivitis in Adults

NCT00941668
View directory record Official record
Conditions
Gingivitis
Interventions
Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 60 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Phase 1 Interventional

Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia

NCT01057108
View directory record Official record
Conditions
Hyperphosphatemia, Chronic Kidney Disease
Interventions
FOSTRAP Chewing Gum, Placebo chewing gum
Other
Lead sponsor
Denver Nephrologists, P.C.
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 6, 2011 · Synced Jun 25, 2026, 11:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

NCT06890676
View directory record Official record
Conditions
Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions
Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection
Other · Procedure
Lead sponsor
Missouri Department of Health and Senior Services
Other
Eligibility
60 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jefferson City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Gum Chewing on Energy Intake and Expenditure

NCT01043471
View directory record Official record
Conditions
Obesity
Interventions
Chewing gum, Water
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 38 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Jun 25, 2026, 11:56 PM EDT
Completed Not applicable Interventional

Dental Plaque Removal Study

NCT01559987
View directory record Official record
Conditions
Gingivitis, Gum Disease
Interventions
Manual Toothbrush only, MTB + Waterpik Ultra Water Flosser 'High', MTB + Floss (MTB+Floss)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Jun 25, 2026, 11:56 PM EDT