Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 10:18 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 253 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gingival Diseases Clear all

Conditions: Dental Plaque, Gingivitis
Interventions: Test Dentifrice, Reference Dentifrice (Colgate Cavity Protection Dentifrice); Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Gingivitis
Interventions: Marketed toothpaste, Marketed Cavity Protection Toothpaste; Drug
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Whittier, California

Conditions: HFrEF - Heart Failure With Reduced Ejection Fraction, HFpEF - Heart Failure With Preserved Ejection Fraction, Group 2 Pulmonary Hypertension
Interventions: JK07; Drug
Lead sponsor: Salubris Biotherapeutics Inc; Industry
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 99 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Hyperphosphatemia, Chronic Kidney Disease
Interventions: FOSTRAP Chewing Gum, Placebo chewing gum; Other
Lead sponsor: Denver Nephrologists, P.C.; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Periodontal Diseases, Gingival Diseases, Gingival Pocket, Gum Bleed, Plaque, Dental
Interventions: SRP + Livfresh Dental Gel, SRP + standard flouride dentifrice; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
Interventions: Free gingival graft; Procedure
Lead sponsor: Mauro Santamaria; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Gingival Recession
Interventions: CelTx, Autologous sub-epithelial connective tissue graft; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Recession, Gingival
Interventions: Use of collagen matrix after subepithelial connective tissue graft harvest; Device
Lead sponsor: Hailey Bivens; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Plaque, Gingivitis
Interventions: 2 mg KSL-W, 4 mg KSL-W, 6 mg KSL-W, 10 mg KSL-W, 20 mg KSL-W, 30 mg KSL-W, 50 mg KSL-W, 75 mg KSL-W, 100 mg KSL-W, Placebo; Drug · Other
Lead sponsor: U.S. Army Medical Research and Development Command; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 135 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Gingivitis, Periodontitis
Interventions: SmartMouth Clinical DDS mouthrinse, 0.12% chlorhexidine rinse, Placebo rinse; Drug
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Alton, Illinois • St Louis, Missouri

Conditions: Gingival Recession
Interventions: Split Mouth Design; Procedure
Lead sponsor: Tufts University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2036
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Dental Plaque, Gingivitis
Interventions: Crest Cavity Protection Toothpaste, Experimental Mouthwash; Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years and older
Enrollment: 138 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Overweight, Obesity
Interventions: Lifestyle modification, Lifestyle modification plus gum; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 75 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Postoperative Ileus
Interventions: Sugared Chewing Gum (Juicy Fruit); Dietary Supplement
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Caries, Tooth Decay, Cavities, Gingivitis
Interventions: Attack of the S. Mutans, Follow-up, SnowWorld; Other
Lead sponsor: University of Washington; Other
Eligibility: 8 Years to 12 Years
Enrollment: 161 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Gingivitis
Interventions: Soft-Picks Advanced, Floss; Device
Lead sponsor: Sunstar Americas; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Gingivitis
Interventions: Abstinence of oral hygiene on select teeth; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 35 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Gingivitis
Interventions: vitamin D3, Placebo; Drug · Other
Lead sponsor: Boston University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gingivitis, Dental Health, Pregnancy, Pregnancy Outcomes, Randomized Controlled Trial, Periodontal Disease, Gum Disease
Interventions: Enhanced Care +; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Gingivitis
Interventions: 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice; Drug
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Whittier, California

Conditions: Gingival Recession
Interventions: enamel matrix derivative, Porcine collagen matrix; Biological · Device
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 30 participants
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Gingival Recession, Palate; Wound
Interventions: palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate, palatal wound covered with a stent; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 70 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Chronic Kidney Disease
Interventions: K2CG chewing gum (20mg chitosan), K2CG chewing gum (60mg chitosan); Other
Lead sponsor: Denver Nephrologists, P.C.; Other
Eligibility: 18 Years and older
Enrollment: 167 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 4
States / cities: Tempe, Arizona • Denver, Colorado • Meridian, Idaho + 1 more

Search by objective public record fields.

A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health

A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and Gingivitis

Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia

Novel Dental Gel as an Adjunct to Scaling and Root Planing

Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial

A Pilot Study of CelTx(TM) (Apligraf®) in the Treatment of Gingival Recession Requiring Root Coverage

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population

SmartMouth Advanced Clinical Formula Clinical Research Design Protocol

Changes of Soft Tissue Grafting: A Randomized Study

A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation

Use of Chewing Gum to Facilitate Appetite Control and Weight Loss

Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery

Improving Oral Health With Serious Games

Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis

Variation in Gingival Inflammatory Responses

Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model

CHEER Oral Health in Pregnancy Study

A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices

Collagen Matrix With and Without Enamel Matrix Derivative

To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting

A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease