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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:11 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 253 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gingival Diseases Clear all

Conditions: Immunosuppression, Periodontal Disease, Healthy Subjects, Healthy Volunteer
Interventions: Not listed
Lead sponsor: National Institute of Dental and Craniofacial Research (NIDCR); NIH
Eligibility: 7 Years to 100 Years
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2012
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cirrhosis, Periodontitis, Gingivitis
Interventions: Dental Cleaning; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Gingivitis, Plaque, Calculus, Dental
Interventions: RF-utilizing powered toothbrush, Control placebo with no RF; Device
Lead sponsor: Home Skinovations Ltd.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Gingivitis
Interventions: Stannous fluoride, Sodium monofluorophosphate; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Gingivitis
Interventions: Sonicare Interproximal (IP) Cleaning Prototype; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Plaque, Dental, Gingivitis
Interventions: Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB; Drug · Other
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Costa Mesa, California

Conditions: Non-Small Cell Lung Cancer, NSCLC, Adenocarcinoma, Heregulin
Interventions: MM-121, Docetaxel; Drug
Lead sponsor: Elevation Oncology; Industry
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 17
States / cities: Tucson, Arizona • Los Angeles, California • Santa Rosa, California + 12 more

Conditions: Gingival Inflammation
Interventions: BLXA4, Placebo oral rinse; Drug
Lead sponsor: The Forsyth Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 127 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Buccal Mucosa Squamous Cell Carcinoma, Floor of Mouth Squamous Cell Carcinoma, Gingival Squamous Cell Carcinoma, Hard Palate Squamous Cell Carcinoma, Lip Squamous Cell Carcinoma, Lower Alveolar Ridge Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Retromolar Trigone Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8, Stage II Lip and Oral Cavity Cancer AJCC v8, Tongue Squamous Cell Carcinoma, Upper Alveolar Ridge Squamous Cell Carcinoma
Interventions: Chest Radiography, Computed Tomography, Fludeoxyglucose F-18, Imaging Agent, Neck Dissection, Planar Imaging, Positron Emission Tomography, Questionnaire Administration, Sentinel Lymph Node Biopsy, Single Photon Emission Computed Tomography; Procedure · Other · Drug
Lead sponsor: NRG Oncology; Other
Eligibility: 18 Years and older
Enrollment: 686 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2036
U.S. locations: 106
States / cities: Birmingham, Alabama • Gilbert, Arizona • Phoenix, Arizona + 80 more

Conditions: Type II Diabetes, Periodontal Disease
Interventions: Triclosan containing toothpaste, Non-triclosan containing toothpaste; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 70 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Gingival Recession
Interventions: Gintuit, autologous Free Gingival Graft (FGG); Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Ileus
Interventions: chewing gum; Other
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: LAD1
Interventions: Ustekinumab; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 12 Years to 65 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Plaque, Gingivitis
Interventions: Experimental Oral Rinse, Placebo; Device
Lead sponsor: You First Services; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Dental Plaque
Interventions: 19416-154-1, W002194-0221P; Device
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Plaque Induced Gingivitis
Interventions: U-shaped Power Toothbrush, Soft Manual Toothbrush; Device
Lead sponsor: Lander Enterprises, LLC; Industry
Eligibility: 5 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Gingival Recession
Interventions: Markman Biologics Microsurfaced ADM, AlloDerm; Biological
Lead sponsor: McGuire Institute; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Gingivitis
Interventions: AMI and campaigns; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Gingivitis
Interventions: Functional Chitosan Chewing Gum, Control Chewing Gum, Oral hygiene measures; Device · Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Plaque
Interventions: 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste, 0.022% Sodium Fluoride mouthwash; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Melbourne, Florida

Conditions: Cardiovascular Disease, Periodontal Disease
Interventions: Early Periodontal Treatment, Usual Dental Hygiene; Procedure
Lead sponsor: Boston University; Other
Eligibility: 20 Years and older
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nicotine Addiction, Smoking Cessation
Interventions: Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer; Drug · Other
Lead sponsor: Creighton University; Other
Eligibility: 19 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Periodontitis
Interventions: collection of gingival crevicular fluid; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Gingivitis, Plaque, Dental
Interventions: Electric Toothbrush, oral health care application; Device · Other
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Loma Linda, California

Search by objective public record fields.

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

Oral Gut Liver Axis in Cirrhosis

Safety and Efficacy of the ToothWave -12 Weeks Calculus Study

A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride

A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities

To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.

A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC

Safety and Preliminary Efficacy of Lipoxin Analog BLXA4-ME Oral Rinse for the Treatment of Gingivitis

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Periodontal Treatment Response in Type II Diabetic Patients

A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva

Does Chewing Gum After Elective Laparoscopic Colectomy Surgery Decrease Ileus?

Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory Pathology

Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health

A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning

Plaque and Gingivitis Evaluation of a U-Shaped Toothbrush in a 30-Day Model

Pilot Study for Healing and Safety Outcomes in Gingival Recession

Good Oral Health - A Bi-level Intervention to Improve Older Adult Oral Health

Functional Chewing Gum in Reduction of Gingival Inflammation

Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

Impact of Gum Infection on Heart Disease

e-Cigarettes Versus NRT Gum for Smoking Cessation

Apoptic Biomarkers of Periodontal Disease

Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush