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ClinicalTrials.gov public records Last synced Nov 10, 2026, 11:32 AM EST

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Showing 337–360 of 3,925 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: HTN Clear all
Recruiting Not applicable Interventional

Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension

NCT05856591
View directory record Official record
Conditions
Food Insecurity, Hypertension, Nutrition, Disease Management
Interventions
Food Resources & Kitchen Skills (FoRKS), Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
35 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Nov 10, 2026, 11:32 AM EST
Completed Phase 4 Interventional

Glycemic Control Of Carvedilol Versus Metoprolol In Patients With Type II Diabetes Mellitus And Hypertension

NCT00060918
View directory record Official record
Conditions
Hypertension
Interventions
carvedilol, metoprolol
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
30 Years to 80 Years
Enrollment
1,210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
50
States / cities
Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional

The Effects of Pork vs. Chicken/Fish in a DASH Diet on Blood Pressure Regulation in Middle Aged and Older Adults

NCT01696097
View directory record Official record
Conditions
Hypertension, Dyslipidemias
Interventions
DASH diet counseling
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
40 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional Results available

Nashville - Hypertension Management Model

NCT04232124
View directory record Official record
Conditions
Hypertension
Interventions
Hypertension Management Model
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
35 Years to 79 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Nash, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Nov 10, 2026, 11:32 AM EST
Withdrawn Phase 2 Interventional

Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension

NCT00323024
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
NX1011
Drug
Lead sponsor
NITROX, LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
6
States / cities
Phoenix, Arizona • La Jolla, California • Newark, Delaware + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2007 · Synced Nov 10, 2026, 11:32 AM EST
Not listed No phase listed Observational Accepts healthy volunteers

African Descent and Glaucoma Evaluation Study

NCT00221923
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2022
U.S. locations
3
States / cities
Birmingham, Alabama • La Jolla, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional Results available

SPYRAL PIVOTAL - SPYRAL HTN-OFF MED Study

NCT02439749
View directory record Official record
Conditions
Hypertension, Vascular Diseases, Cardiovascular Diseases
Interventions
Symplicity Spyral™ multi-electrode renal denervation system, Sham Procedure
Device · Procedure
Lead sponsor
Medtronic Vascular
Industry
Eligibility
20 Years to 80 Years
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
30
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional

Preparing a Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

NCT05796648
View directory record Official record
Conditions
Hypertension, Obesity, Healthy Nutrition, Blood Pressure
Interventions
RN-CHeFRx
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Nov 10, 2026, 11:32 AM EST
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of Phentermine and B12 on Weight Loss Among Obese Patients

NCT01719185
View directory record Official record
Conditions
Obesity, Hypertension
Interventions
Phentermine and B12, Phentermine
Drug
Lead sponsor
Dr. Michael Lang
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2015 · Synced Nov 10, 2026, 11:32 AM EST
Recruiting Not applicable Interventional

Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

NCT07363343
View directory record Official record
Conditions
Hypertension, Postpartum Preeclampsia
Interventions
Nifedipine and Enalapril, Nifedipine and Labetalol
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Nov 10, 2026, 11:32 AM EST
Terminated No phase listed Observational

Evaluate Real-World Use of Next Generation Infusion Pumps to Administer Remodulin

NCT05060315
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Remunity Pump for Remodulin
Combination Product
Lead sponsor
United Therapeutics
Industry
Eligibility
22 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Morrisville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Nov 10, 2026, 11:32 AM EST
Terminated Phase 2 Interventional Accepts healthy volunteers

Treatment of Elevated Blood Pressures in Early Pregnancy

NCT05955040
View directory record Official record
Conditions
Elevated Blood Pressure, Pregnancy Induced Hypertension
Interventions
Nifedipine, Labetalol
Drug
Lead sponsor
Marshall University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

A Proof of Concept Study of Electrical Discharge Produced Nitric Oxide for Inhalation

NCT02305550
View directory record Official record
Conditions
Hypertension, Pulmonary
Interventions
electrical pulsed plasma discharge synthesis of nitric oxide
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional Results available

Reducing Clinical Inertia in Hypertension Treatment: A Pragmatic Trial

NCT01145391
View directory record Official record
Conditions
Hypertension
Interventions
Active Outreach to Patients and Providers
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 79 Years
Enrollment
591 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Nov 10, 2026, 11:32 AM EST
Terminated Phase 3 Interventional Results available

PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)

NCT00729365
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Ramipril, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 50 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
6
States / cities
Gainesville, Florida • Chicago, Illinois • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Nov 10, 2026, 11:32 AM EST
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress

NCT02431936
View directory record Official record
Conditions
Hypertension, Stress, Psychological, Blood Pressure
Interventions
Prazosin, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Nov 10, 2026, 11:32 AM EST
Terminated No phase listed Observational

Therapeutic Drug Monitoring of Cardiac Medications

NCT03667781
View directory record Official record
Conditions
Hypertension, Coronary Artery Disease
Interventions
Therapeutic drug monitoring
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
77 participants
Timeline
2018 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Nov 10, 2026, 11:32 AM EST
Completed Phase 2 Interventional Accepts healthy volunteers

Primary Prevention of Hypertension in Obese Adolescents

NCT00288158
View directory record Official record
Conditions
Obesity, Pre-Hypertension, Hyperuricemia
Interventions
Allopurinol, Probenecid, Placebo
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
11 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Nov 10, 2026, 11:32 AM EST
Recruiting Phase 4 Interventional

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

NCT07217678
View directory record Official record
Conditions
Glaucoma, Open-Angle Glaucoma, Ocular Hypertension, Glaucoma Suspect
Interventions
Durysta, Bimatoprost Intracameral Implant 10 µg
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Nov 10, 2026, 11:32 AM EST
Completed Phase 1Phase 2 Interventional Results available

Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension

NCT00964678
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Carvedilol
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Nov 10, 2026, 11:32 AM EST
Terminated Phase 2 Interventional Results available

Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant

NCT05027425
View directory record Official record
Conditions
Hepatocellular Carcinoma, Cirrhosis, Portal Hypertension
Interventions
Durvalumab, Tremelimumab, Liver Transplant
Drug · Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
St Louis, Missouri • Cincinnati, Ohio • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Nov 10, 2026, 11:32 AM EST
Recruiting Not applicable Interventional

The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease

NCT07561034
View directory record Official record
Conditions
Pulmonary Hypertension, Interstitial Lung Disease
Interventions
Home Exercise Program, Aerobic Plus Strength Training, Home Exercise Program, Aerobic Only
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Nov 10, 2026, 11:32 AM EST
Not listed No phase listed Observational

Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary Hypertension

NCT03459716
View directory record Official record
Conditions
Scleroderma, Pulmonary Hypertension
Interventions
No intervention
Other
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
56 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 10, 2021 · Synced Nov 10, 2026, 11:32 AM EST
Completed Not applicable Interventional

Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics

NCT04392284
View directory record Official record
Conditions
Insulin Resistance, Obesity, Diabetes, Hypertension, Dyslipidemias, Metabolic Syndrome
Interventions
Diet Counseling, Exercise Counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 10, 2026, 11:32 AM EST