Independent directory Public ClinicalTrials.gov records United States
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Showing 25–48 of 560 matching trials from the live ClinicalTrials.gov search.
Conditions
Hearing Loss, Sensorineural
Interventions
FX-345, Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 67 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Sarasota, Florida • Spartanburg, South Carolina • San Antonio, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Direct-to-Consumer Hearing Aids and Listening Effort

NCT05855005
Conditions
Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
DTC Hearing Aids
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Enrolling by invitation No phase listed Observational

Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

NCT06696456
Conditions
Otoferlin Gene-mediated Hearing Loss
Interventions
Not listed
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
3
States / cities
Iowa City, Iowa • Boston, Massachusetts • Philadelphia, Pennsylvania
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases, Asymmetrical Hearing Loss, Single-Sided Deafness
Interventions
HiResolution Bionic Cochlear Implant
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Sarasota, Florida • Seattle, Washington
Conditions
Sensorineural Hearing Loss
Interventions
Extended Wear Hearing Aid
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Shenandoah, Texas
Conditions
Hearing Loss, Hearing Aids, OTC Hearing Aids
Interventions
HA-HCP, OTC-HCP, OTC-R, OTC-SF
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Conditions
Hearing Loss, Sensorineural
Interventions
Standard Electrical Categorical Loudness Scaling task (Standard-ELS), Fast Electrical Categorical Loudness Scaling task (Fast-ELS)
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Lone Tree, Colorado
Conditions
Hearing Loss
Interventions
Hearing Aids
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Noise Induced Hearing Loss
Interventions
SPI-1005 200mg, SPI-1005 400mg, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
5
States / cities
Miami, Florida • Kansas City, Kansas • Charleston, South Carolina + 2 more
Conditions
Hearing Loss
Interventions
Standard Referral, Specialty Telemedicine Access for Referrals (STAR)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
3 Years to 21 Years
Enrollment
8,060 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Anchorage, Alaska
Conditions
Hearing Loss
Interventions
Standard School Screening and Referral, Enhanced mHealth Screening, Specialty Telemedicine Referral
Other
Lead sponsor
University of Arkansas
Other
Eligibility
3 Years to 11 Years
Enrollment
18,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Childhood Medulloblastoma
Interventions
Audiometric Test, Auditory Brainstem Response, Biospecimen Collection, Cisplatin, Cyclophosphamide, Lomustine, Magnetic Resonance Imaging, Quality-of-Life Assessment, Radiation Therapy, Sodium Thiosulfate, Survey Administration, Vincristine
Procedure · Drug · Other + 1 more
Lead sponsor
Children's Oncology Group
Network
Eligibility
4 Years to 21 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
106
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 92 more
Conditions
Hearing Loss
Interventions
Hearing
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Sensorineural Hearing Loss, Low-Frequency Residual Hearing
Interventions
CI624 Slim 20 Electrode
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Bilateral Hearing Loss
Interventions
Cogmed Working Memory Training Program
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
7 Years to 16 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Hearing Loss
Interventions
Attention to Variability (ATV), Placebo
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users (Oticon Study)

NCT03771287
Conditions
Hearing Impairment, Hearing Loss, Sensorineural
Interventions
Oticon OpenSound Navigator speech enhancement algorithm, Oticon omni-directional microphone algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 13 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Hearing Impaired
Interventions
Talker variability
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Sensorineural Hearing Loss, Bilateral, Cochlear Implant
Interventions
Commercially available cochlear implant and AI system
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
9
States / cities
Englewood, Colorado • Baltimore, Maryland • Ann Arbor, Michigan + 6 more
Conditions
Hearing Loss, Adult-Onset, Speech Intelligibility, Hearing Loss, Extreme
Interventions
Cochlear implant
Device
Lead sponsor
Craig D. Workman, PhD
Other
Eligibility
18 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hearing Study: Sensitivity to Features of Speech Sounds

NCT03666676
Conditions
Hearing Loss, Sensorineural
Interventions
Signal processing to improve intelligibility
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Rochester, New York
Conditions
Hearing Loss, Language Impairment
Interventions
Feedback with massed trials, Feedback with spaced trials, No feedback with massed trials, No feedback with spaced trials
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
5 Years to 9 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Hearing Loss
Interventions
Categorical loudness scaling based fitting using the research fitting system., Behavioural fitting using Custom Sound Suite (CSS 6.3) Software
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lone Tree, Colorado
Conditions
Retinal Degeneration, Age-Related Macular Degeneration, Retinitis Pigmentosa, Hydroxychloroquine Retinopathy, Usher Syndromes, Late-Onset Retinal Degeneration, Cone Dystrophy, Cone Rod Dystrophy, Rod Cone Dystrophy, Rod Dystrophy
Interventions
Adaptive optics imaging
Device
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
21 Years and older
Enrollment
100 participants
Timeline
2021 – 2028
U.S. locations
2
States / cities
Bethesda, Maryland • Silver Spring, Maryland