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Showing 1–24 of 252 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Health-Related Quality of Life Clear all
Completed Phase 3 Interventional Results available

Efficacy and Safety Study of Mepolizumab Adjunctive Therapy in Participants With Severe Eosinophilic Asthma on Markers of Asthma Control

NCT02281318
View directory record Official record
Conditions
Asthma
Interventions
Mepolizumab, Placebo, SOC
Biological · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years and older
Enrollment
556 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
24
States / cities
Birmingham, Alabama • Fresno, California • Long Beach, California + 20 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Sep 15, 2026, 4:20 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Real-World Evidence Study Evaluating the Effects of the Human Optimization Project Protocol on Methylation Biomarkers and Health-Related Quality of Life in Women

NCT07548645
View directory record Official record
Conditions
Longevity, Women's Health
Interventions
Human Optimization Project
Dietary Supplement
Lead sponsor
Human Optimization Project
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Quality of Life in Patients Who Have Undergone Stem Cell Transplant

NCT00128960
View directory record Official record
Conditions
Long Term Psychological Affects on HSCT
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis

NCT04273867
View directory record Official record
Conditions
Hypersensitivity Pneumonitis, Chronic Hypersensitivity Pneumonitis, Interstitial Lung Disease, Extrinsic Allergic Alveolitis, Health-related Quality of Life
Interventions
Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 15, 2026, 4:20 PM EDT
Suspended Not applicable Interventional

Co-Active Therapeutic Theatre (Co-ATT) for Dual-Diagnosis Patients

NCT06187701
View directory record Official record
Conditions
Mental Health Issue, Substance Use Disorders
Interventions
Co-Active Therapeutic Theatre (Co-ATT)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed Phase 4 Interventional Results available

Study of VESIcare® In Overactive Bladder (OAB) Subjects to Evaluate Symptom Bother and Health Related Quality of Life

NCT00573508
View directory record Official record
Conditions
Urinary Bladder, Overactive
Interventions
Placebo, Solifenacin Succinate
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
768 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
59
States / cities
Montgomery, Alabama • Phoenix, Arizona • Tucson, Arizona + 53 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2010 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Pyruvate Kinase Deficiency Natural History Study

NCT02053480
View directory record Official record
Conditions
Pyruvate Kinase Deficiency, Congenital Non-Spherocytic Hemolytic Anemia
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
19
States / cities
Phoenix, Arizona • Palo Alto, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Sep 15, 2026, 4:20 PM EDT
Terminated Not applicable Interventional

Effectiveness of the Ivivi Torino II, Pulsed Radio Frequency Device, on Narcotic Use, Pain and Quality of Life Following Shoulder Arthroscopic Rotator Cuff Repair.

NCT01507818
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Ivivi Torino II, Inactive Sham device
Device
Lead sponsor
Amp Orthopedics, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
New Orleans, Louisiana • Jackson, Mississippi • Taos, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 8, 2012 · Synced Sep 15, 2026, 4:20 PM EDT
Completed Phase 1 Interventional

Improving Quality-of-life and Depressive Symptoms of Combat Veterans Via Internet-based Intervention

NCT01231711
View directory record Official record
Conditions
Depression, Post-Traumatic Stress Disorder, Functional Status
Interventions
Vets Prevail
Behavioral
Lead sponsor
Prevail Health Solutions, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2010 · Synced Sep 15, 2026, 4:20 PM EDT
Recruiting Not applicable Interventional

Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers

NCT07415564
View directory record Official record
Conditions
Cancer Metastatic, Symptoms and Signs, Quality of Life
Interventions
Symptom Management and Survivorship Handbook + Coaching, Symptom Management and Survivorship Handbook
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Quality of Life in Patients Undergoing Surgery or Brachytherapy for Stage II Prostate Cancer

NCT00052481
View directory record Official record
Conditions
Prostate Cancer
Interventions
quality-of-life assessment
Procedure
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
Up to 75 Years · Male only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
13
States / cities
San Francisco, California • Washington D.C., District of Columbia • Iowa City, Iowa + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Sep 15, 2026, 4:20 PM EDT
Active, not recruiting No phase listed Observational

Health Related Quality of Life Following Hepatectomy for Colorectal Liver Metastasis: Global and Disease Specific Changes Over Time

NCT02399995
View directory record Official record
Conditions
Colorectal Liver Metastasis
Interventions
HRQoL questionnaires.
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?

NCT06798584
View directory record Official record
Conditions
Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
Interventions
FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional

Lung Cancer Information Study (LCIS-R01)

NCT01924416
View directory record Official record
Conditions
Non-Small-Cell Lung Cancer
Interventions
Enhanced Care (intervention group and comparison group), Usual care (routine chemotherapy cycles and imaging studies)
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Expanding Knowledge About and Evaluating Services for Incarcerated Pregnant and Postpartum Women in Arkansas

NCT04421235
View directory record Official record
Conditions
Health Problems in Pregnancy, Childbirth Problems, Maternal Care Patterns, Quality of Life, Emotional Stress, Health Care Acceptability, Health Risk Behaviors, Parent-Child Relations
Interventions
Childbirth support
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Health-Related Quality of Life in Gay Men With Localized Prostate Cancer

NCT00828633
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oral Health and Oral Health-Related Quality of Life in Early Stage Breast Cancer Survivors

NCT01272570
View directory record Official record
Conditions
Breast Cancer, Xerostomia
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 26, 2015 · Synced Sep 15, 2026, 4:20 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

ProGo Menopause Wellbeing Study

NCT07611305
View directory record Official record
Conditions
Menopause Related Conditions
Interventions
Salmon protein hydrolysate (SPH) powder formulated into a tablet format, Microcrystalline Cellulose
Dietary Supplement
Lead sponsor
Hofseth Biocare ASA
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed No phase listed Observational

Life After Pediatric Sepsis Evaluation

NCT01415180
View directory record Official record
Conditions
Septic Shock
Interventions
Not listed
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
1 Month to 18 Years
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
11
States / cities
Phoenix, Arizona • Los Angeles, California • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Sep 15, 2026, 4:20 PM EDT
Recruiting No phase listed Observational

Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists

NCT07702461
View directory record Official record
Conditions
Obesity & Overweight, Diabetes (DM)
Interventions
Glucagon-Like Peptide-1 Agonist (GLP-1)
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Recruiting Not applicable Interventional

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

NCT07250061
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Self-Help Cognitive Processing Therapy, Women Veterans Network (WoVeN), Treatment as Usual
Behavioral · Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Completed Phase 4 Interventional Results available

Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.

NCT02970669
View directory record Official record
Conditions
Heart Failure, Reduced Ejection Fraction
Interventions
sacubitril/valsartan (LCZ696), enalapril, matching placebo sacubitril/valsartan (LCZ696), matching placebo enalapril
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
23
States / cities
Fort Payne, Alabama • Beverly Hills, California • Stockton, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Sep 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional

Examining the Effects of a Remotely-delivered, Racially-tailored Exercise Training Program for Immediate and Sustained Improvements in Walking Dysfunction, Symptoms, and Health-related Quality of Life (HRQOL) Among African-Americans With Multiple Sclerosis (MS) Residing in Rural Environments.

NCT05516537
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Guidelines for Exercise in Multiple Sclerosis (GEMS), FLEX Stretching and Toning Program
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 15, 2026, 4:20 PM EDT
Active, not recruiting No phase listed Observational

Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic

NCT04500600
View directory record Official record
Conditions
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Quality-of-Life Assessment, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13,378 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 15, 2026, 4:20 PM EDT