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Showing 49–72 of 529 matching trials from the live ClinicalTrials.gov search.
Conditions
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
Interventions
Anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
13 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Hyde Park, New York
Completed Phase 3 Interventional Results available

SPI-1005 for the Treatment of Meniere's Disease

NCT04677972
Conditions
Meniere Disease, Ménière
Interventions
Ebselen, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Little Rock, Arkansas • Los Angeles, California • Roseville, California + 8 more
Completed Not applicable Interventional Results available

Evaluation of Extended Wear Technology

NCT04882800
Conditions
Hearing Loss
Interventions
Lyric extended wear hearing aid device A, Lyric extended wear hearing aid with fitting modification device B
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Narberth, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Applying the Use of Motivational Tools to Auditory Rehabilitation

NCT01843777
Conditions
Hearing Loss
Interventions
Standard-of-Care, Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Speech in Noise Using Noninvasive Stimulation

NCT07176936
Conditions
Traumatic Brain Injury, Hearing Loss
Interventions
Cymba Conchae stimulation, Earlobe stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 55 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional

Computer-Based Auditory Rehabilitation

NCT02147847
Conditions
Presbycusis
Interventions
Video game based training 1, Video game based training 2
Behavioral
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
50 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • Brighton, Massachusetts • New City, New York
Conditions
Retinitis Pigmentosa, Usher Syndrome Type 2
Interventions
RNA antisense oligonucleotide for intravitreal injection
Drug
Lead sponsor
Laboratoires Thea
Industry
Eligibility
12 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • Portland, Oregon + 1 more
Conditions
Hearing Loss, Unilateral
Interventions
Personal remote microphone (RM) system, Subjective Questionnaire
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
5 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Conditions
Bilateral Sensorineural Hearing Loss, Cochlear Implant, Hearing Preservation, Electric and Acoustic Simulation
Interventions
binaural processing over time, binaural processing over time for children and adults with normal hearing
Behavioral
Lead sponsor
Hearts for Hearing
Other
Eligibility
5 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Hearing Healthcare Assessment in Rural Communities

NCT05786794
Conditions
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Interventions
Patient Navigation Program for Hearing Health Care
Behavioral
Lead sponsor
Matthew Bush, MD
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
9
States / cities
Campbellsville, Kentucky • Campton, Kentucky • Elkton, Kentucky + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Usability of the CP950 Sound Processor

NCT02727842
Conditions
Hearing Loss
Interventions
CP950 Sound Processor, Wireless programming pod
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
3
States / cities
Englewood, Colorado • New York, New York • Oklahoma City, Oklahoma
Conditions
Hearing Loss, Hearing Disorders
Interventions
Remote CI Counseling, In-Person CI Counseling
Device · Other
Lead sponsor
Matthew Bush, MD
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lexington, Kentucky
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Apple Hearing Study

NCT04172766
Conditions
Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus
Interventions
Not listed
Lead sponsor
Apple Inc.
Industry
Eligibility
18 Years and older
Enrollment
300,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Hearing Loss, Bilateral (Causes Other Than Tumors)
Interventions
Hearing aid use
Device
Lead sponsor
University of Southern California
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Los Angeles, California
Conditions
Hearing Loss, Bilateral
Interventions
Parent-Mediated Intervention (PMI)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
5 Years to 8 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Hearing Loss, Bilateral
Interventions
Electrocochleography
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Rochester, Minnesota • St Louis, Missouri • Chapel Hill, North Carolina + 2 more
Enrolling by invitation No phase listed Observational

Long Term Follow-up Study of AAVAnc80-antiVEGF Gene Therapy

NCT07503613
Conditions
Vestibular Schwannoma
Interventions
Not listed
Lead sponsor
Akouos, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Los Angeles, California • Kansas City, Missouri • St Louis, Missouri + 1 more
Conditions
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Head and Neck Carcinoma of Unknown Primary, Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Nasopharyngeal Squamous Cell Carcinoma, Metastatic Oral Cavity Squamous Cell Carcinoma, Metastatic Oropharyngeal Squamous Cell Carcinoma, Metastatic Paranasal Sinus Squamous Cell Carcinoma, Nasopharyngeal Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma, Paranasal Sinus Squamous Cell Carcinoma, Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Nasopharyngeal Squamous Cell Carcinoma, Recurrent Oral Cavity Squamous Cell Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Recurrent Paranasal Sinus Squamous Cell Carcinoma, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Nasopharyngeal Carcinoma AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Sinonasal Cancer AJCC v8
Interventions
Audiometric Test, Interview
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Recruiting Not applicable Interventional Accepts healthy volunteers

Understanding Aided Speech Perception in Noise

NCT06377215
Conditions
Hearing Impairment, Sensorineural, Spatial Perception, Aging, Hearing Aids
Interventions
Open-source master hearing aid
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Restoration of Spectral Resolution With Hearing-aid Amplification

NCT03850678
Conditions
Hearing Loss
Interventions
Hearing Aid
Device
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
40 Years to 75 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Smith-Lemli-Opitz Syndrome, Cone-Rod Dystrophy, Hearing Loss
Interventions
Antioxidants, Cholesterol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)

NCT02903355
Conditions
Noise-induced Hearing Loss
Interventions
D-methionine, Placebo
Drug
Lead sponsor
Southern Illinois University
Other
Eligibility
21 Years to 45 Years
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Fort Jackson, South Carolina
Conditions
Hearing Loss
Interventions
Phonak Audeo Infinio Hearing Aid, Competitor Device A
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Aurora, Illinois