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ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:13 PM EDT

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Showing 409–432 of 2,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Heart Failure Clear all
Completed Phase 2 Interventional

Safety and Feasibility Trial of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia

NCT01556022
View directory record Official record
Conditions
Myocardial Ischemia
Interventions
ADRCs processed by the Celution System, Placebo Comparator: Lactated Ringer's and Subject's Blood
Device
Lead sponsor
Cytori Therapeutics
Industry
Eligibility
20 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Gainesville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2016 · Synced Oct 25, 2026, 1:13 PM EDT
Completed No phase listed Observational

OVATIO CRT and SITUS OTW LV Lead Post Approval Study

NCT00795873
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
ELA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
33
States / cities
Mesa, Arizona • Beverly Hills, California • Encino, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2013 · Synced Oct 25, 2026, 1:13 PM EDT
Completed No phase listed Observational

Pilot Study: Hypovitaminosis D, Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure

NCT00887666
View directory record Official record
Conditions
Congestive Heart Failure, Hypovitaminosis D, Hyperparathyroidism
Interventions
Not listed
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Not applicable Interventional Results available

Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction

NCT01542502
View directory record Official record
Conditions
Heart Failure
Interventions
Anakinra, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Oct 25, 2026, 1:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient-Reported Outcomes as an Indicator of Disease Transitions in Heart Failure

NCT04264845
View directory record Official record
Conditions
Heart Failure
Interventions
Provider Focus, Patient Interview, PROs/Clinical Data Integration
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
1,033 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Not applicable Interventional Results available

Sensor-controlled Digital Game for Heart Failure Self-management

NCT03947983
View directory record Official record
Conditions
Heart Failure
Interventions
Sensor-controlled digital game (SCDG), Sensor Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
55 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated Phase 4 Interventional

IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches

NCT07053475
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Iron Deficiency, Iron-deficiency Anemia (IDA)
Interventions
Ferric Carboxymaltose, Ferrous Sulfate
Drug
Lead sponsor
Syed Hamza Mufarrih
Other
Eligibility
18 Years to 100 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Not applicable Interventional Results available

Promote Q Cardiac Resynchronization Therapy Defibrillator (CRT-D) and Quartet Left Ventricular Heart Lead Study

NCT00990665
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D and LV lead (Quartet™ lead and Promote Q® device system)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Glendale, California + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Oct 25, 2026, 1:13 PM EDT
Not listed Not applicable Interventional

Continued Access Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D

NCT02374801
View directory record Official record
Conditions
Heart Failure (NYHA Class III and Ambulatory IV)
Interventions
SonR automatic optimization feature turned ON ("AV+VV").
Device
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 11, 2019 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated No phase listed Observational

Retrospective Evaluation of Carvedilol Versus Captopril in CHF Patients

NCT00249067
View directory record Official record
Conditions
Heart Failure, Heart Murmurs
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2007 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated Not applicable Interventional Results available

The Role of Sleep Disordered Breathing in Heart Failure Admissions

NCT02505867
View directory record Official record
Conditions
Sleep Apnea Syndromes, Heart Failure
Interventions
Adaptive Servo Ventilation
Device
Lead sponsor
Rami Khayat
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Not applicable Interventional

Telephone Intervention in Heart Failure Patients

NCT00057057
View directory record Official record
Conditions
Heart Failure, Congestive, Cardiomyopathy
Interventions
Telephone Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 25, 2026, 1:13 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure

NCT07083011
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
68Ga-FAPI (gallium-68-labeled fibroblast activation protein inhibitor)
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of Aliskiren in Post Myocardial Infarction Patients (ASPIRE)

NCT00414609
View directory record Official record
Conditions
Myocardial Infarction
Interventions
Aliskiren, placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years and older
Enrollment
820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Novartis US, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 13, 2012 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics and Metabolism of [14C] BMS-986231 in Healthy Male Participants

NCT03210909
View directory record Official record
Conditions
Heart Decompensation, Acute
Interventions
BMS-986231
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 25, 2026, 1:13 PM EDT
Recruiting No phase listed Observational

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

NCT07436299
View directory record Official record
Conditions
Heart Failure (HF), Atrial Fibrillation (AF)
Interventions
Not listed
Lead sponsor
Oslo University Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Cleveland, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Phase 3 Interventional Results available

Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity

NCT04788511
View directory record Official record
Conditions
Obesity
Interventions
Semaglutide, Placebo (semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
50
States / cities
Fairhope, Alabama • Beverly Hills, California • Los Angeles, California + 41 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated Not applicable Interventional Results available

Managed Ventricular Pacing ("MVP") Trial

NCT00281099
View directory record Official record
Conditions
Heart Disease
Interventions
ICD (Implantable Cardioverter Defibrillator)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,031 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
50
States / cities
Anchorage, Alaska • Little Rock, Arkansas • North Little Rock, Arkansas + 47 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Oct 25, 2026, 1:13 PM EDT
Recruiting Phase 2 Interventional

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

NCT07202000
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Activin ligand-trap biological therapy, Placebo, Normal Saline
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated Not applicable Interventional

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

NCT02783716
View directory record Official record
Conditions
Heart Failure
Interventions
Subcutaneous adipose tissue collection, Peripheral arterial tonometry (PAT)
Procedure · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 25, 2026, 1:13 PM EDT
Withdrawn Phase 1 Interventional

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

NCT05322616
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
JK07, Matching Placebo
Drug
Lead sponsor
Salubris Biotherapeutics Inc
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
7
States / cities
Stanford, California • Boston, Massachusetts • Rochester, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 25, 2026, 1:13 PM EDT
Completed No phase listed Observational

DR REGISTRY: Prospective Observational Study of ADHF Patients With Insufficient Response to Diuretics

NCT04877652
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
Standard of care
Other
Lead sponsor
Revamp Medical Ltd.
Industry
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Oct 25, 2026, 1:13 PM EDT
Terminated No phase listed Observational

Comparison of Different Locations for Pulse Oximetry Probes in Cardiovascular (CV) Patients With Poor Peripheral Perfusion

NCT01128036
View directory record Official record
Conditions
Congestive Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 9, 2011 · Synced Oct 25, 2026, 1:13 PM EDT
Completed Phase 2Phase 3 Interventional

Jarvik 2000 Heart as a Bridge to Cardiac Transplantation - Pivotal Trial

NCT00591799
View directory record Official record
Conditions
Heart Failure
Interventions
The Jarvik 2000 Ventricular Assist System
Device
Lead sponsor
Jarvik Heart, Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2013 · Synced Oct 25, 2026, 1:13 PM EDT