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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:57 PM EDT

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Showing 313–336 of 372 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Heart Rate Fast Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A MHealth System for Patients with POTS

NCT06296914
View directory record Official record
Conditions
POTS - Postural Orthostatic Tachycardia Syndrome
Interventions
POTSapp, Waitlist Control
Device
Lead sponsor
Jami Warren
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional Results available

Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies

NCT01139814
View directory record Official record
Conditions
Atrial Flutter, Ventricular Tachycardia
Interventions
Amigo catheter robot
Device
Lead sponsor
Catheter Robotics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
11
States / cities
Newport Beach, California • Redwood City, California • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Oct 23, 2026, 1:57 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

fMRI in Postural Tachycardia Syndrome

NCT04137757
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Lower Body Negative Pressure, Sham Pressure
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

NCT06292104
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
multimodal diagnostic testing
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
14 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Completed No phase listed Observational

An Observational Study (Called RETAF-PS) Using a Patient Survey to Learn More About Treatment Outcomes in Patients With Irregular and Often Rapid Heartbeat (Atrial Fibrillation) Treated With Apixaban in a Real World Setting

NCT05471830
View directory record Official record
Conditions
Prevention of Thromboembolic Events, Atrial Fibrillation
Interventions
Apixaban
Drug
Lead sponsor
Bayer
Industry
Eligibility
45 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Whippany, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Oct 23, 2026, 1:57 PM EDT
Terminated No phase listed Observational

LifeVest Post-CABG Registry

NCT01448005
View directory record Official record
Conditions
Sudden Cardiac Death, Ventricular Fibrillation, Ventricular Tachycardia, Ventricular Dysfunction, Myocardial Ischemia
Interventions
wearable defibrillator (LifeVest)
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
Sacramento, California • Atlanta, Georgia • Takoma Park, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 23, 2026, 1:57 PM EDT
Not listed Phase 4 Interventional

Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort

NCT05481177
View directory record Official record
Conditions
Long Haul COVID, Postural Orthostatic Tachycardia Syndrome
Interventions
Ivabradine
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional Results available

Imaging With a Radio Tracer to Guide VT Ablations

NCT01250912
View directory record Official record
Conditions
Ventricular Tachycardia, Arrhythmia
Interventions
123I-metaiodobenzylguanidine
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Oct 23, 2026, 1:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

START & STOPP in GWI

NCT03560830
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
2 submaximal exercise stress tests
Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional

Vagus Nerve Stimulation in Treatment of Postural Orthostatic Tachycardia Syndrome

NCT03930914
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Parasym (TM) Transcutaneous Electrical Nerve Stimulation (TENS) Device
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional

CyberHeart's Cardiac Arrhythmia Ablation Treatment: Patients With Refractory Ventricular Tachycardia/Fibrillation

NCT02661048
View directory record Official record
Conditions
Tachycardia, Ventricular
Interventions
CyberHeart System
Device
Lead sponsor
Varian, a Siemens Healthineers Company
Industry
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 23, 2026, 1:57 PM EDT
Recruiting No phase listed Observational

Inappropriate Sinus Tachycardia Registry

NCT05107635
View directory record Official record
Conditions
Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome
Interventions
AtriCure Commercially Available Devices
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
12
States / cities
Loma Linda, California • Palo Alto, California • Redwood City, California + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Active, not recruiting Early Phase 1 Interventional

Autonomic Determinants of POTS - Pilot 2

NCT04140721
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Placebo oral tablet, Moxonidine Pill
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Terminated Not applicable Interventional Results available

Stepwise Approach To sUbstrate Modification for Ventricular Tachycardia

NCT01546207
View directory record Official record
Conditions
Ventricular Tachycardia, Catheter Ablation, Tachycardia, Ventricular
Interventions
catheter-based ablation
Procedure
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Birmingham, Alabama • Maywood, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 23, 2026, 1:57 PM EDT
Recruiting Phase 2 Interventional

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

NCT07189936
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome, Postural Tachycardia Syndrome (POTS), SARS CoV 2 Infection, Long COVID19
Interventions
To Measure levels of circulating monocyte/ T cell doublets at Baseline, To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment, To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment, To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA, To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo, To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA, To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo
Drug · Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Terminated Phase 3 Interventional Results available

Mental Stress Reduction in Defibrillator Patients

NCT00624520
View directory record Official record
Conditions
Cardiomyopathy, Dilated, Arrhythmia, Anger, Stress
Interventions
Cognitive Behavioral Stress Management (CBSM), Patient Education
Behavioral · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Oct 23, 2026, 1:57 PM EDT
Terminated Phase 3 Interventional Results available

Continuation of Antiarrhythmics Following Ventricular Tachycardia Catheter Ablation

NCT04208997
View directory record Official record
Conditions
Tachycardia, Ventricular, Catheter Ablation
Interventions
Antiarrhythmic drug
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional

Acute Study to Collect Electrical Signals From the Heart Using a Special Lead

NCT02772380
View directory record Official record
Conditions
Tachycardia, Ventricular Arrhythmias
Interventions
Defibrillation following induction of VT/VF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
14
States / cities
Scottsdale, Arizona • Hartford, Connecticut • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Not applicable Interventional

A Shared Medical Appointment Intervention for Quality of Life Improvement in POTS

NCT05454137
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Shared medical appointment
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
21 Years to 79 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 23, 2026, 1:57 PM EDT
Withdrawn Not applicable Interventional

Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia

NCT00721032
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
MRI guided VT ablation, Increased dose of amiodarone
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Phase 4 Interventional Results available

RIGHT: Rhythm ID Going Head-to-Head Trial

NCT00148954
View directory record Official record
Conditions
Tachycardia
Interventions
VITALITY 2 Implantable Cardioverter Defibrillator, Medtronic Implantable Cardioverter Defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,962 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2012 · Synced Oct 23, 2026, 1:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Mayo AVC Registry and Biobank

NCT03049254
View directory record Official record
Conditions
Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases, Sudden Cardiac Arrest, Sudden Cardiac Death, Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Ventricular Cardiomyopathy, Familial Dilated Cardiomyopathy, Cardiovascular Abnormalities, Sarcoidosis, Cardiac Arrhythmia, Cardiac Sarcoidosis, Myocarditis, Inflammatory Cardiomyopathy, Ventricular Tachycardia, Right Ventricular Outflow Tract Ventricular Tachycardia
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 23, 2026, 1:57 PM EDT
Completed Phase 4 Interventional Results available

Antiarrhythmic Effects of Spironolactone in Patients With ICDs

NCT04495712
View directory record Official record
Conditions
Ventricular Arrhythmias
Interventions
spironolactone, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 9, 2020 · Synced Oct 23, 2026, 1:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Menopause Racing Heart Study

NCT05062057
View directory record Official record
Conditions
Menopause Related Conditions
Interventions
Adhesive ambulatory ECG recording patches
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years to 62 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 23, 2026, 1:57 PM EDT