- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- GEN-003 Vaccine (30μg of each antigen), GEN-003 Vaccine (60μg of each antigen), Matrix-M2 Adjuvant (25μg), Matrix-M2 Adjuvant (50μg), Matrix-M2 Adjuvant (75μg)
- Biological
- Lead sponsor
- Genocea Biosciences, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 16
- States / cities
- Birmingham, Alabama • San Diego, California • San Francisco, California + 12 more
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Showing 1–24
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- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- Observational
- Biological
- Lead sponsor
- Genocea Biosciences, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 13
- States / cities
- Birmingham, Alabama • San Diego, California • San Francisco, California + 10 more
- Conditions
- HSV-2
- Interventions
- AIC316, Placebo
- Drug
- Lead sponsor
- AiCuris Anti-infective Cures AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 6
- States / cities
- Miami, Florida • Indianapolis, Indiana • Portland, Oregon + 3 more
- Conditions
- Bacterial Vaginosis
- Interventions
- Metronidazole
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 26 Years · Female only
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2010
- U.S. locations
- 2
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Genital Herpes
- Interventions
- Not listed
- Lead sponsor
- Centers for Disease Control and Prevention
- Federal
- Eligibility
- 16 Years to 55 Years
- Enrollment
- 2,500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 3
- States / cities
- Baltimore, Maryland • Boston, Massachusetts • New York, New York
- Conditions
- Genital Herpes
- Interventions
- mRNA-1608, BEXSERO
- Biological
- Lead sponsor
- ModernaTX, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 303 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 23
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Beverly Hills, California + 20 more
- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- VCL-HB01, VCL-HM01, PBS
- Biological
- Lead sponsor
- Vical
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Hollywood, Florida • Indianapolis, Indiana + 4 more
- Conditions
- Recurrent Genital Herpes Simplex Type 2
- Interventions
- ABI-1179, ABI-1179 Placebo
- Drug
- Lead sponsor
- Assembly Biosciences
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Kansas City, Missouri • Rochester, New York • Seattle, Washington
- Conditions
- Herpes Simplex
- Interventions
- Not listed
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- Up to 30 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2007
- U.S. locations
- 5
- States / cities
- Baltimore, Maryland • St Louis, Missouri • Rochester, New York + 2 more
- Conditions
- Chronic Hepatitis C Infection
- Interventions
- Valacyclovir, Placebo
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Hepatitis C Virus Infection, Infection, Herpesvirus 2, Human
- Interventions
- Valacyclovir
- Drug
- Lead sponsor
- G.V. (Sonny) Montgomery VA Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Genital Herpes
- Interventions
- Valacyclovir
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- GEN-003 with Matrix M-2, GEN-003, Placebo
- Biological
- Lead sponsor
- Genocea Biosciences, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 143 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Indianapolis, Indiana • Cincinnati, Ohio + 4 more
- Conditions
- Herpes Genitalis
- Interventions
- VCL-HB01, Phosphate-buffered saline
- Biological · Other
- Lead sponsor
- Vical
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 261 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 15
- States / cities
- Birmingham, Alabama • San Diego, California • Hollywood, Florida + 12 more
- Conditions
- HSV-2
- Interventions
- pPJV7630 administered by PMED
- Biological
- Lead sponsor
- PowderMed
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 2
- States / cities
- Portland, Oregon • Houston, Texas
- Conditions
- Genital Herpes
- Interventions
- acyclovir
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- Matrix-M2, GEN-003, Placebo
- Biological · Drug
- Lead sponsor
- Genocea Biosciences, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 131 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • San Diego, California • San Francisco, California + 5 more
- Conditions
- HSV-2 Infection, Herpes Simplex Virus Infection
- Interventions
- Diagnostic Test: NOWDx HSV-2 Test
- Device
- Lead sponsor
- NOWDiagnostics, Inc.
- Industry
- Eligibility
- 18 Years to 64 Years
- Timeline
- 2023
- U.S. locations
- 3
- States / cities
- Tempe, Arizona • Coral Gables, Florida • Lexington, Kentucky
- Conditions
- Herpes Simplex Type II
- Interventions
- TDF, Placebo Vaginal Gel, Vaginal TFV Gel, Placebo Tablets
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 73 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Genital Herpes
- Interventions
- acyclovir
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Genital Herpes Simplex Type 2
- Interventions
- BNT163, Placebo
- Biological · Other
- Lead sponsor
- BioNTech SE
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 318 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 6
- States / cities
- Tempe, Arizona • Chicago, Illinois • Raleigh, North Carolina + 3 more
- Conditions
- Sexually Transmitted Infections, HIV Infections
- Interventions
- Not listed
- Lead sponsor
- University of Mississippi Medical Center
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Herpes Simplex Type 2
- Interventions
- HerpV and QS-21, Placebo
- Drug
- Lead sponsor
- Agenus Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 5
- States / cities
- Portland, Oregon • Houston, Texas • Seattle, Washington
- Conditions
- Genital Herpes
- Interventions
- acyclovir, valacyclovir
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Seattle, Washington