Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 10, 2026, 5:11 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

NCT04748861
Conditions
High Intensity Exercise, Normal Cognition, Exercise Intervention
Interventions
Indoor Cycling (IC)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
65 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

CASH- Children Active to Stay Healthy

NCT01821313
Conditions
Childhood Obesity, Inflammation
Interventions
Moderate exercise, High Intensity Interval Exercise
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent, Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
Interventions
High-intensity physical exercise, Low-intensity physical exercise
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Berkeley, California • Hayward, California • San Francisco, California
Conditions
Exercise-induced Muscle Soreness, Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Cartilage Turnover
Interventions
NEM® brand eggshell membrane powder, curQ+® brand highly absorbable curcumin, EM Placebo, Curc Placebo, NEM® plus curQ+® combination
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
College Station, Texas
Conditions
Multimorbidity, Physical Deconditioning
Interventions
Motivational Interviewing Techniques, Physical Therapy Interventions, Education, Qualitative Interview
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida, Stroke, Poliomyelitis, Multiple Sclerosis, Brain Injuries
Interventions
HIFT
Behavioral
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fort Smith, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of High-Intensity Exercise on Biological Age

NCT05156918
Conditions
Exercise
Interventions
Exercise, Non Exercise
Other
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Terminated Not applicable Interventional Accepts healthy volunteers

High Fat Meal and Postprandial TG Levels With and Without Exercise Intervention

NCT05291767
Conditions
Ketogenic Diet, Exercise
Interventions
Diet, Exercise
Other · Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 45 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans

NCT02892331
Conditions
Obesity, Insulin Resistance, Sedentary Lifestyle
Interventions
Moderate intensity exercise training (MOD-INT), High Intensity exercise training (HI-INT)
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
35 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Greenville, North Carolina
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Classroom Break, Cognition, and Fitness in Elementary School Children

NCT06258941
Conditions
Healthy Volunteers
Interventions
MF-HIIT, HIIT-only, MF-only, Sedentary activity
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
8 Years to 12 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Royal Center, Indiana
Conditions
Exercise Performance
Interventions
Hyperbaric chamber, Ambient pressure
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Murray, Utah
Not listed No phase listed Observational Accepts healthy volunteers

Leggings With Resistance Bands on Caloric Expenditure During Exercise

NCT06547060
Conditions
Health Behavior
Interventions
Exercise leggings
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acute Renal Injury During High Intensity Training

NCT03678285
Conditions
Acute Kidney Injury, Exercise
Interventions
HIFRT Workout
Other
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Laramie, Wyoming
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Functional Capacity in Older Adults With Short Session High Intensity Interval Training

NCT03750006
Conditions
Frailty
Interventions
Short session HIIT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Multiple Sclerosis,Gait, Exercise
Interventions
Moderate paced continuous gait training, High Intensity Interval gait training
Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
End Stage Renal Disease
Interventions
CoQ10, Placebo, HB-HIIT, Observational
Dietary Supplement · Drug · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Sacramento, California • Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Intensity on ADHD Symptoms

NCT06753253
Conditions
Attention Deficit Disorder with Hyperactivity, Attention Deficit Hyperactivity Disorder, ADHD
Interventions
Cycling Exercise
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years to 26 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kent, Ohio
Conditions
Decompression Sickness, SCUBA Diving
Interventions
High intensity exercise
Other
Lead sponsor
University of Split
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

High Intensity Interval Exercise in Diastolic Heart Failure

NCT02147613
Conditions
Diastolic Heart Failure
Interventions
High intensity interval training, Moderate intensity exercise training
Other
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Phoenix, Arizona • Scottsdale, Arizona
Completed Not applicable Interventional Results available

High Intensity Interval Training in Endometrial Cancer

NCT04025229
Conditions
Endometrial Cancer
Interventions
HIIT exercise
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Subcortical Lesions, Stroke
Interventions
HIIT intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of High Intensity Interval Exercise on Executive Function

NCT02270528
Conditions
High Intensity Interval Exercise (HIIE), Pain Perception, Wisconsin Card Sorting Task
Interventions
Exercise, Cognitive Task
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

"Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"

NCT05143801
Conditions
Hypoxemia, Physiological Stress
Interventions
High-intensity interval exercise with surgical face mask in a temperate environment, High-intensity interval exercise with surgical face mask in a hot environment, High-intensity interval exercise without using a surgical face mask in a hot environment, High-intensity interval exercise without using a surgical face mask in a temperate environment
Device · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Results available

High Intensity Interval Exercise SCI

NCT04940598
Conditions
Spinal Cord Injuries, Cardiometabolic Diseases
Interventions
high intensity interval exercise, No-exercise control group
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama