Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 9:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1633–1656 of 7,258 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: High-Risk Clear all

Conditions: Anal Dysplasia, Carcinoma in Situ
Interventions: Gliolan, Vitamin D3 cholecalciferol), Photodynamic Therpay; Drug · Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic Leukemia
Interventions: Calaspargase Pegol-mknl, Cyclophosphamide, Cytarabine, Daunorubicin Hydrochloride, Dexamethasone, Doxorubicin Hydrochloride, Laboratory Biomarker Analysis, Mercaptopurine, Methotrexate, Pegaspargase, Pharmacological Study, Prednisone, Radiation Therapy, Thioguanine, Vincristine Sulfate; Drug · Other · Radiation
Lead sponsor: Children's Oncology Group; Network
Eligibility: 2 Years to 30 Years
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2021
U.S. locations: 27
States / cities: Birmingham, Alabama • Orange, California • Palo Alto, California + 22 more

Conditions: Psychosis, First Episode Psychosis, Clinical High Risk for Psychosis
Interventions: Not listed
Lead sponsor: University of New Mexico; Other
Eligibility: 15 Years to 30 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Pancreatic Ductal Adenocarcinoma, Familial Pancreatic Cancer, FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome
Interventions: Not listed
Lead sponsor: Immunovia, Inc.; Industry
Eligibility: Not listed
Enrollment: 1,349 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 13
States / cities: Stanford, California • New Haven, Connecticut • Chicago, Illinois + 8 more

Conditions: Neuroblastoma
Interventions: anti-GD2 murine IgG3 monoclonal antibody 3F8; Biological
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: Not listed
Enrollment: 291 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Risky Sexual Behavior, Emotional Regulation, Adolescent Behavior
Interventions: Formative Research- Content Translation, Formative Research- Content Feedback and Acceptability; Behavioral
Lead sponsor: Klein Buendel, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Golden, Colorado • Eugene, Oregon • Providence, Rhode Island

Conditions: Upper Airway Surgery
Interventions: Hi-VNI; Device
Lead sponsor: Natasha Mirza; Other
Eligibility: 22 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: HIV
Interventions: Social Network Intervention, Counsel, Test, and Treat; Behavioral
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older · Male only
Enrollment: 856 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Cleveland, Ohio • Milwaukee, Wisconsin

Conditions: Tobacco Use Cessation
Interventions: Varenicline, Nicotine Patch, Placebo Patch, Placebo Tablet, Questionnaires, Counseling Sessions, Lab Session, Saliva Test; Drug · Behavioral · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 204 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Prostatic Neoplasm
Interventions: Perflutren Lipid Microsphere Intravenous Suspension; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm
Interventions: Best Practice, Biospecimen Collection, Bone Metastases Treatment, Computed Tomography, Conventional Radiotherapy, Magnetic Resonance Imaging, Patient Observation, Questionnaire Administration, Stereotactic Body Radiation Therapy; Other · Procedure · Radiation
Lead sponsor: NRG Oncology; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2034
U.S. locations: 624
States / cities: Fairbanks, Alaska • Gilbert, Arizona • Phoenix, Arizona + 450 more

Conditions: Major Depression, Generalized Anxiety, Emotions
Interventions: Academic Performance Feedback; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 35 Years
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
Interventions: Unstuck & On Target: High School, Treatment as Usual; Behavioral · Other
Lead sponsor: Children's National Research Institute; Other
Eligibility: 14 Years to 22 Years
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Rockville, Maryland

Conditions: Diabetes, Hyperglycemia
Interventions: Best Practice Advisory; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: Not listed
Enrollment: 7,232 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Preleukemia, Myelodysplastic Syndromes, Refractory Acute Myeloid Leukemia
Interventions: BH-30236, Venetoclax; Drug
Lead sponsor: BlossomHill Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 13
States / cities: Duarte, California • Los Angeles, California • Palo Alto, California + 10 more

Conditions: Infant, Very Low Birth Weight
Interventions: Similac special care 30, Similac human milk fortifier; Dietary Supplement
Lead sponsor: University of Oklahoma; Other
Eligibility: 1 Day to 10 Weeks
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Bronchiolitis, Heliox, Pediatrics
Interventions: Vapotherm-Heliox; Device
Lead sponsor: Case Western Reserve University; Other
Eligibility: Up to 2 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Hypertension
Interventions: Health Literacy-Focused High Blood Pressure Intervention; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 60 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Ellicott City, Maryland

Conditions: COVID-19
Interventions: Bamlanivimab; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 12 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries, Anesthesia
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Myeloma
Interventions: Hyperbaric oxygen; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 75 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Hypertension, Substance Abuse, Asthma, Depression
Interventions: Primary care redesign; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 10
States / cities: Birmingham, Alabama • Martinez, California • San Francisco, California + 6 more

Conditions: Self-regulation, Respiratory Sinus Arrhythmia
Interventions: Mom Power Intervention; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 2
States / cities: New Orleans, Louisiana

Conditions: High Blood Glucose, High Cholesterol, High Cholesterol/Hyperlipidemia, Blood Sugar; High, Obesity & Overweight, Diabetes Type 2
Interventions: FELLAship; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older · Male only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

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PDT Plus Vitamin D3 for Anal Dysplasia

Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Feasibility of an Early Detection Program for Early Psychosis on a College Campus

A Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma

Education Program to Reduce Risky Behavior in Adolescents Ph I

High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery

Prevention of HIV Infection in High-Risk Social Networks of African American Men Who Have Sex With Men (MSM)

Reward Sensitivity and Pharmacotherapy for Smoking Cessation

Detection of High Grade Prostate Cancer With Subharmonic Ultrasound Imaging, A Pilot Study

Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial

Neural Mechanisms of Real-world Emotions and Internalizing

A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth

Comparison of Intraoperative Best Practice Advisory Reminders to Protocolize Insulin Administration Versus Standard Care in Patients at High Risk of Hyperglycemia

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants

Helium-oxygen Gas Mixtures Delivered by a High Flow Nasal Cannula in Bronchiolitis

Health Literacy-Focused Program to Improve Blood Pressure Control in Korean Americans

A Real World Study of Bamlanivimab in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)

Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery

Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT

Linking Former Inmates to Primary Care

Mom Power With High-Adversity Mothers and Children

FELLAShip to Better Health