Independent directory Public ClinicalTrials.gov records United States
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Showing 505–528 of 2,196 matching trials from the live ClinicalTrials.gov search.
Conditions
Hypertension
Interventions
NanoGreens, Whey protein, Calcium pills
Dietary Supplement
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Chesterfield, Missouri
Conditions
Glaucoma
Interventions
Dorzolamide 2%-timolol 0.5%, Brimonidine 0.2%-0.5% timolol 0.5
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
40 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Hypertension
Interventions
Telehealth Follow-up Visits, Surveys, Devices
Behavioral · Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Tampa, Florida
Not listed Phase 4 Interventional Accepts healthy volunteers

Chymase Angiotensin-(1-12) Axis In Hypertensive Disease

NCT05644769
Conditions
Hypertension
Interventions
Determine the presence of Human sequence Ang-(1-12) on no medication, Human sequence Ang-(1-12) on Lisinopril 40mg every day
Other · Drug
Lead sponsor
Trinity Hypertension & Metabolic Research Institute
Other
Eligibility
40 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Carrollton, Texas
Conditions
Diabetes, Hypertension
Interventions
Clinical pharmacist-based intervention
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
4,622 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Pulmonary Arterial Hypertension
Interventions
St Jude Medical C7 Dragonfly Optical Coherence Tomography (OCT), Boston Scientific Intravascular Ultrasound
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Hypertension
Interventions
Adherence Intervention, Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Autonomic Nervous System Disorders, Pure Autonomic Failure, Shy-Drager Syndrome, Orthostatic Hypotension, Dysautonomic
Interventions
Angiotensin-(1-7), Saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Sickle Cell Anemia, Pulmonary Hypertension
Interventions
Nitric Oxide, INO Pulse - NO Delivery System
Drug · Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

AVACEN Hand Heating on Fasting Blood Glucose

NCT04018586
Conditions
Hyperglycemia, Hypertension
Interventions
AVACEN 100, AVACEN 100 Heat Only, AVACEN Sham
Device
Lead sponsor
Jeff Moore
Other
Eligibility
18 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Results available

The PCORnet Blood Pressure Home Monitoring Study

NCT03796689
Conditions
Hypertension
Interventions
Smartphone-linked HBPM and associated app, Standard HBPM
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
2,238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
San Francisco, California • Gainesville, Florida • New Orleans, Louisiana + 1 more
Conditions
Hypertension
Interventions
Access Nourish
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Hypertension
Interventions
MK-8457, Placebo for MK-8457
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Miramar, Florida • Tacoma, Washington
Conditions
Heart Failure
Interventions
Dietary Approaches to Stop Hypertension Diet
Other
Lead sponsor
University of Georgia
Other
Eligibility
65 Years to 110 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure

NCT00175110
Conditions
Hypertension
Interventions
herbal therapy/botanical therapy (Hibiscus sabdariffa)
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
30 Years to 70 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Hypertension, Left Ventricular Diastolic Dysfunction
Interventions
Nebivolol
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Systolic Blood Pressure Intervention Trial

NCT01206062
Conditions
Hypertension
Interventions
Intensive control of SBP, Standard control of SBP
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
50 Years and older
Enrollment
9,361 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Obesity, Hypertension, Hyperlipidemias, Diet Modification
Interventions
In-store POP education, Online POP education
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years to 75 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Dyspnea, Hypertension, Acute Heart Failure
Interventions
Stage 1: Clevidipine (double-blinded), Stage 1: Placebo (double-blinded), Stage 2: Clevidipine (open-label), Stage 2: Standard of Care (open-label)
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
9
States / cities
Montgomery, Alabama • Tucson, Arizona • St Louis, Missouri + 5 more
Conditions
Hypertension
Interventions
self-management protocol for hypertension care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
San Diego, California • San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text My Hypertension BP Meds NOLA

NCT05074173
Conditions
Hypertension
Interventions
Text
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
New Orleans, Louisiana
Conditions
Hypertension
Interventions
A structured, telephone-based educational outreach to encourage HBPM
Other
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Hypertension in Pregnancy, Hypertension, Obesity
Interventions
Upper Arm Cylindrical Blood Pressure Cuff, Forearm Conical Blood Pressure Cuff
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 2 Interventional Results available

Remodulin® to Oral Treprostinil Transition

NCT01588405
Conditions
Pulmonary Arterial Hypertension
Interventions
UT-15C SR
Drug
Lead sponsor
United Therapeutics
Industry
Eligibility
15 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Phoenix, Arizona • Tucson, Arizona • St Louis, Missouri + 3 more