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ClinicalTrials.gov public records Last synced Nov 6, 2026, 9:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1609–1632 of 3,919 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Hypertension Clear all

Conditions: Hypertension, Pulmonary
Interventions: Carbon Monoxide; Drug
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hypertension, Pulmonary
Interventions: Ambrisentan; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 8 Years to 18 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2022
U.S. locations: 4
States / cities: Aurora, Colorado • Boston, Massachusetts • Ann Arbor, Michigan + 1 more

Conditions: Hypertension, Cardiovascular Disease Risk
Interventions: Complex quality improvement intervention; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 535 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Kinston, North Carolina

Conditions: Hypertension
Interventions: Medisafe; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 413 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Menlo Park, California

Conditions: Metabolic Syndrome, Hypertension
Interventions: Placebo, Enalapril 5mg, Enalapril 10mg, Sitagliptin; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hypertension, Blood Pressure
Interventions: Pharmacist Drug Therapy Management; Other
Lead sponsor: University of Louisiana Monroe; Other
Eligibility: 4 Years to 20 Years
Enrollment: 266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: West Monroe, Louisiana

Conditions: Open-angle Glaucoma, Ocular Hypertension
Interventions: Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension, Brinzolamide 10 mg/ml (AZOPT) eye drops, suspension, Timolol 5 mg/ml eye drops, solution; Drug
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 523 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Hypertension
Interventions: Level of noise and environment (public vs private) while taking blood pressure measurement; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pulmonary Hypertension
Interventions: To discern micro-RNA specific for right and left heart induced PH; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Hypertension, Hypercholesterolemia, Diabetes, Medication Adherence
Interventions: Refill synch; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 691 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Pre-Eclampsia, Pregnancy Induced Hypertension
Interventions: Not listed
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1,100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: San Diego, California

Conditions: Hypertension
Interventions: LED bed; Device
Lead sponsor: LED Intellectual Properties, LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Rockdale, Texas

Conditions: Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus, Metabolic Syndrome, Inflammation, Kidney Transplant Failure, Dietary Habits
Interventions: Plant-based diet; Behavioral
Lead sponsor: George Washington University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Gestational Hypertension, Preeclampsia, Chronic Hypertension With Pre-Eclampsia Complicating Childbirth, HELLP Syndrome
Interventions: Home blood pressure monitoring; Device
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older · Female only
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Charleston, South Carolina • Greenville, South Carolina

Conditions: Hypertension, Stroke
Interventions: Not listed
Lead sponsor: Columbia University; Other
Eligibility: 30 Years and older
Enrollment: 1,244 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 30
States / cities: Mobile, Alabama • Scottsdale, Arizona • Tucson, Arizona + 23 more

Conditions: Chronic Kidney Diseases, Hypertension
Interventions: Intervention, Control; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 2,026 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hypertension, Left Ventricular Hypertrophy
Interventions: amlodipine/benazepril; Drug
Lead sponsor: Novartis; Industry
Eligibility: 55 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: East Hanover, New Jersey

Conditions: Pulmonary Arterial Hypertension, Exercise Associated Pulmonary Arterial Hypertension
Interventions: PET-CT Imaging with [89Zr]-bevacizumab; Diagnostic Test
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pulmonary Artery Hypertension
Interventions: Metformin, Placebo, mHealth Intervention, Usual Care; Drug · Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Nashvile, Tennessee

Conditions: Primary Pulmonary Hypertension
Interventions: LIQ861 Inhaled Treprostinil; Drug
Lead sponsor: Liquidia Technologies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 25
States / cities: Phoenix, Arizona • Los Angeles, California • Sacramento, California + 19 more

Conditions: Idiopathic Pulmonary Arterial Hypertension.
Interventions: Albuterol., Normal saline placebo; Drug
Lead sponsor: American Medical Association Foundation; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Diabetes, Hyperlipidemia, Hypertension, Cardiovascular Disease
Interventions: CVRS Intervention; Behavioral
Lead sponsor: Korey Kennelty; Other
Eligibility: 55 Years and older
Enrollment: 402 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 18
States / cities: Gainesville, Florida • Tampa, Florida • Pocatello, Idaho + 14 more

Conditions: Heart Diseases, Hypertension, Pulmonary
Interventions: tezosentan, placebo; Drug
Lead sponsor: Idorsia Pharmaceuticals Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 274 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 9
States / cities: Stanford, California • New York, New York • Durham, North Carolina + 5 more

Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases
Interventions: Symplicity Spyral™ multi-electrode renal denervation system, Sham Procedure; Device · Procedure
Lead sponsor: Medtronic Vascular; Industry
Eligibility: 20 Years to 80 Years
Enrollment: 366 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 30
States / cities: Huntsville, Alabama • Scottsdale, Arizona • Los Angeles, California + 26 more

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Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension

Long-term Ambrisentan Extension Study for Pediatric Patients Who Participated in AMB112529

Improving Care for Patients With High Blood Pressure

Medication Adherence Improvement Support App For Engagement - Blood Pressure

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

Before-after Comparison of Pharmacist Drug Therapy Management in Pediatric Hypertension

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Determining Change In Blood Pressure Due to Environment and Loudness

Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

The Effect of Synching Prescription Refills on Adherence

Multi-Omics for Maternal Health After Preeclampsia

A Controlled Study to Investigate the Effect of Multi-wave Light Emitting Diode (LED) Bed on Blood Pressure and Endothelial Function

Plant-based Diet for Kidney Transplant Recipients

Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring

Levels of Inflammatory Markers in the Treatment of Stroke-An SPS3 Ancillary Study

Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease

Effects of Amlodipine/Benazepril in Reducing Left Ventricular Hypertrophy in Patients With High Risk Hypertension

Angiogenic Imaging in Pulmonary Arterial Hypertension

Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil

Albuterol and Dynamic Hyperinflation in Idiopathic Pulmonary Arterial Hypertension

MEDication Focused Outpatient Care for Underutilization of Secondary Prevention

Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery

SPYRAL PIVOTAL - SPYRAL HTN-OFF MED Study