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ClinicalTrials.gov public records Last synced Nov 11, 2026, 10:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 364 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Hypertensive Disorder of Pregnancy Clear all

Conditions: Pre-Eclampsia
Interventions: recombinant human relaxin; Drug
Lead sponsor: Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies; Industry
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 2
States / cities: Lexington, Kentucky • Cincinnati, Ohio

Conditions: Hypertension in Pregnancy, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Interventions: Digital Blood Pressure Monitoring System, Mobile health application; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Septic Shock, Endotoxemia
Interventions: TORAYMYXIN PMX-20R (PMX cartridge), Standard medical care for septic shock; Device · Other
Lead sponsor: Spectral Diagnostics (US) Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 33
States / cities: Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 30 more

Conditions: Acute Kidney Injury, Chronic Kidney Disease, Hypertension
Interventions: Iodohippurate, 24 hour ambulatory Blood Pressure, Peripheral Arterial Tonometry, Pulse Wave Velocity, Gadolinium; Drug · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 7 Years to 17 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Pre-Eclampsia, Hypertension in Pregnancy, Pregnancy Complications, Hypertension, Pregnancy-Induced
Interventions: Furosemide, Placebo; Drug · Other
Lead sponsor: Melanie Maykin, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Pregnancy Related, Pre-Eclampsia
Interventions: Modified natural cycle, Programmed cycle; Procedure
Lead sponsor: JHSPH Center for Clinical Trials; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 788 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 15
States / cities: San Francisco, California • Sunnyvale, California • Orange, Connecticut + 12 more

Conditions: Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension, Eclampsia; Complicating Pregnancy
Interventions: MFeast ENHANCED, MFeast Usual Care; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity, Endotoxemia, Inflammation
Interventions: Green Tea Extract, Placebo; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
Interventions: Web-based educational and motivational modules, Information and Screening Group; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 151 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Kidney Diseases
Interventions: Dietary education program; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Rochester, New York

Conditions: Diabetes, Hypertension, Diabetic Kidney Disease
Interventions: Pharmacist telehealth intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Renal Dysfunction, Hypertension
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Renal Artery Stenosis, Hypertension, Renovascular
Interventions: iCAST™ Rx Stent System; Device
Lead sponsor: Atrium Medical Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 12
States / cities: Fremont, California • Loveland, Colorado • Clearwater, Florida + 9 more

Conditions: Pulmonary Hypertension of Newborn
Interventions: INOmax; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 27 Weeks to 40 Weeks
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 30
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 27 more

Conditions: Pre-Eclampsia, Obesity, Gestational Diabetes, Gestational Hypertension
Interventions: Women's Health Delaware Food Farmacy, Usual Standard of Care; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older · Female only
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Pregnancy Induced Hypertension, Preeclampsia and Eclampsia, Gestational Hypertension
Interventions: L-citrulline, Placebo; Drug
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years and older · Female only
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Obstetric Labor Complications, Preeclampsia, Thrombocytopenia
Interventions: Not listed
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 445 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2003
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia, Cardiovascular Complication
Interventions: Placebo, Dapagliflozin 10mg Tab; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Chronic Kidney Diseases, Hypertension, Blood Pressure
Interventions: strict blood pressure control; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 13 Years to 30 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hypertension in Pregnancy
Interventions: Impendence Cardiography; Diagnostic Test
Lead sponsor: Marshall University; Other
Eligibility: 15 Years to 45 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Huntington, West Virginia

Conditions: Chronic Hypertension in Pregnancy
Interventions: Amlodipine besylate; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Gestational Diabetes Mellitus, Preeclampsia, Gestational Hypertension, Pre-term Delivery, Delivery of Small for Gestational Age (SGA) Baby
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Pre-eclampsia
Interventions: Phenylephrine, Ephedrine; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:; Drug
Lead sponsor: Daniel Benjamin; Other
Eligibility: Up to 21 Years
Enrollment: 3,520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 43
States / cities: Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more

Search by objective public record fields.

Evaluation of the Safety of Relaxin in Preeclampsia

Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock

Severe Sepsis in Children - IMPRESS-C

Furosemide vs. Placebo for Severe Antepartum Hypertension

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension

Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD

Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD)

Effect of Obesity on Long-term Clinical Outcomes After Kidney Donation

Renal Stent Placement for the Treatment of Renal Artery Stenosis in Patients With Resistant Hypertension

Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension

Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women

Role of L-citrulline in Prevention of Pregnancy Associated Hypertension

Platelet Count Trends in Pre-eclamptic Parturients

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

Pilot to Examine Risk and Feasibility of Remote Management of BP From Childhood Into Early Adulthood

Treatment of Severe Hypertension With ICG Directed Therapy

Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation

User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study

Phenylephrine Versus Ephedrine in Pre-eclampsia

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care