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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:36 AM EDT

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Showing 217–240 of 253 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ICD Clear all
Completed Not applicable Interventional

A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

NCT03495297
View directory record Official record
Conditions
Ventricular Arrythmia
Interventions
ommitence of defibrillation testing
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
965 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
7
States / cities
Orlando, Florida • Atlanta, Georgia • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

Utility of the Audible Alert in Current Generation Medtronic Implantable Cardioverter-defibrillators

NCT01605500
View directory record Official record
Conditions
Patients With a Generation 2 Medtronic Implantable Cardioverter-defibrillator(ICD)
Interventions
Not listed
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Not applicable Interventional Results available

Safety and Clinical Performance of the Protecta ICD and CRT-D

NCT00982397
View directory record Official record
Conditions
Tachyarrhythmias, Heart Failure, Ventricular Dysfunction
Interventions
Protecta VR-ICD, Protecta DR-ICD or CRT-D
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
2,770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
29
States / cities
Birmingham, Alabama • Mesa, Arizona • Fort Smith, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 21, 2026, 7:36 AM EDT
Not listed No phase listed Observational

Safety of Magnetic Resonance Imaging in Non-MRI Conditional Pacemakers and ICD Devices

NCT02906189
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
MRI
Radiation
Lead sponsor
Banner Health
Other
Eligibility
18 Years to 85 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

Reconstruction of 12-Lead Electrogram From Intracardiac Signals From Defibrillators During or After Implantation

NCT00890461
View directory record Official record
Conditions
ICD
Interventions
CT scan of the chest without contrast
Radiation
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

OptiSense™ Performance in Detecting Atrial Episodes

NCT00870324
View directory record Official record
Conditions
Tachyarrhythmias, Atrial Fibrillation
Interventions
OptiSense Lead, Tendril Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 21, 2026, 7:36 AM EDT
Recruiting Not applicable Interventional

Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

NCT03588286
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Electrophysiology study (EPS), Standard Care, Cardiac Magnetic Resonance (CMR)
Procedure · Other
Lead sponsor
Western Sydney Local Health District
Other
Eligibility
18 Years to 85 Years
Enrollment
1,058 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

Observational Study of ICD and Pacemaker Sensing in the Presence of IMED-4 Operation

NCT02191696
View directory record Official record
Conditions
Heart Failure
Interventions
IMED-4 recording
Device
Lead sponsor
Intersection Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Encinitas, California • Palm Springs, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2015 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds

NCT02693262
View directory record Official record
Conditions
Heart Failure, ICD, Chronotropic Incompetence
Interventions
CLS Mode on Biotronik CRT-D, Accelerometer Mode on Biotronik CRT-D
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 99 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Phase 4 Interventional

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications

NCT00729703
View directory record Official record
Conditions
Tachycardia
Interventions
OVATIO DR 6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
5
States / cities
Atlanta, Georgia • Decatur, Georgia • Mandeville, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2015 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

The MagnaSafe Registry: Determining the Risks of Magnetic Resonance Imaging (MRI) in the Presence of Pacemakers and Implantable Cardioverter Defibrillators (ICDs)

NCT00907361
View directory record Official record
Conditions
Need for MRI Imaging With Pacemaker or, Implantable Cardioverter Defibrillator Implanted
Interventions
MRI with pacemaker or ICD
Device
Lead sponsor
Scripps Health
Other
Eligibility
18 Years and older
Enrollment
2,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
21
States / cities
Burbank, California • La Jolla, California • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2015 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Not applicable Interventional

Improving Safety of Lead Extraction Procedures by Traction Force Sensing

NCT03842124
View directory record Official record
Conditions
Cardiac Implantable Electronic Device Infection, Cardiovascular Infections
Interventions
Force gauge
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase 1 Trial to Determine Dosimetry, Biodistribution and Safety of LMI 1195-101 in Healthy Subjects and Patients With Heart Failure

NCT00891241
View directory record Official record
Conditions
Heart Failure
Interventions
LMI 1195-101
Drug
Lead sponsor
Lantheus Medical Imaging
Industry
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
2
States / cities
Hartford, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 21, 2026, 7:36 AM EDT
Terminated Not applicable Interventional

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

NCT06543446
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
ICD implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
3,290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Portland, Maine • Baltimore, Maryland • Boston, Massachusetts + 10 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Not applicable Interventional Results available

Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy

NCT02819973
View directory record Official record
Conditions
Sudden Cardiac Death, Heart Failure
Interventions
Educational Video1, Educational Video 2, Usual Care 3
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
14
States / cities
San Francisco, California • Washington D.C., District of Columbia • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 21, 2026, 7:36 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable

NCT06763549
View directory record Official record
Conditions
Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncopation, Syncope, Ischemic Cardiovascular Disease, STEMI, STEMI (ST Elevation MI), Atrial Fibrillation (AF), Atrial Enlargement, LVF, Conduction Defect, Conduction Abnormalities, Heart Block, Valvular Diseases, Cardiac Output, Low, Stroke Volume, Stroke Volume Variation, Hyperkalemia, Hypercalcemia, Hypocalcemia, LV Dysfunction, QT Prolongation, Sudden Cardiac Death Due to Cardiac Arrhythmia, Ventricular Arrhythmia, Pacing, Pacing Induced Dyssynchrony, Silent Ischemia, Pericarditis, Sleep Related Breathing Disorder, RSA, Apnea, Obstructive, Cardiac Output Measurement, Respiratory Impedance, CRT And/or ICD, Infarction, Cardiomyopathies, Primary, Hypertrophy
Interventions
SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C, SUBPROTOCOL D, SUBPROTOCOL E, SUBPROTOCOL F, SUBPROTOCOL G, SUBPROTOCOL H
Device
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 21, 2026, 7:36 AM EDT
Enrolling by invitation No phase listed Observational

TRAjectories and CLinical ExpeRiences of ICD Therapy Study

NCT05116176
View directory record Official record
Conditions
Implantable Defibrillator User
Interventions
Implantable cardioverter-defibrillators
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
65 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 21, 2026, 7:36 AM EDT
Recruiting No phase listed Observational

Implantable Cardioverter Defibrillator (ICD Registry)

NCT01999140
View directory record Official record
Conditions
Heart Failure, Nonischemic Cardiomyopathy, Ischemic Cardiomyopathy, Ventricular Arrhythmia, Complications; Device, Cardiac
Interventions
Not listed
Lead sponsor
American College of Cardiology
Other
Eligibility
Not listed
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Phase 4 Interventional Results available

POWER (Pulse Width Optimized Waveform Evaluation Trial)

NCT00311181
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronization Therapy (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Birmingham, Alabama • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 21, 2026, 7:36 AM EDT
Completed Not applicable Interventional Results available

Intravascular Ultrasound (IVUS) Imaging During Transvenous Lead Extraction

NCT04055740
View directory record Official record
Conditions
Device Malfunction, ICD, Pacemaker Lead Dysfunction
Interventions
IVUS Imaging
Device
Lead sponsor
University of Chicago
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational

Effects of Monopolar Electrocautery Use During Surgery on Implanted Cardiac Defibrillators

NCT01572246
View directory record Official record
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
Optimal placement of return pad
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 24, 2017 · Synced Oct 21, 2026, 7:36 AM EDT
Completed No phase listed Observational Results available

Extracellular Matrix Marker of Arrhythmia Risk (EMMA)

NCT00376532
View directory record Official record
Conditions
Myocardiopathies, Ischemia, Myocardial, Arrythmia, Death, Sudden, Cardiac
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 21, 2026, 7:36 AM EDT
Not listed Phase 1 Interventional

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

NCT00050765
View directory record Official record
Conditions
Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions
MyoCell™ Autologous Myoblasts
Drug
Lead sponsor
Bioheart, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
5
States / cities
Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2006 · Synced Oct 21, 2026, 7:36 AM EDT