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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:43 PM EDT

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Showing 97–120 of 192 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Ibuprofen Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Phase II Study of AP0302 5% Versus a Vehicle Comparator

NCT02324985
View directory record Official record
Conditions
Pain, Delayed Onset Muscle Soreness
Interventions
S-Ibuprofen Topical Gel 5%, Vehicle Topical Gel
Drug
Lead sponsor
Aponia Laboratories, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Results available

Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen

NCT01334944
View directory record Official record
Conditions
Pain, Fever
Interventions
Intravenous ibuprofen
Drug
Lead sponsor
Cumberland Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
13
States / cities
San Diego, California • Danbury, Connecticut • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

NCT01901393
View directory record Official record
Conditions
Pain
Interventions
IV ibuprofen, Ketorolac
Drug
Lead sponsor
Cumberland Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
Fort Lauderdale, Florida • Chicago, Illinois • Tupelo, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 21, 2026, 1:43 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.

NCT01377441
View directory record Official record
Conditions
Inflammatory Response
Interventions
Ibuprofen, Placebo/Saline solution
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 21, 2026, 1:43 PM EDT
Not yet recruiting Phase 4 Interventional

Post-op Analgesia of Nail Unit Procedures

NCT07820969
View directory record Official record
Conditions
Nail Diseases
Interventions
Suzetrigine, Oxycodone/Acetaminophen, Acetaminophen, Ibuprofen
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ibuprofen Inhibits Human Sweet Taste

NCT06291337
View directory record Official record
Conditions
Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants, Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy Participants
Interventions
Inhibition of Sweet Taste by Ibuprofen Oral Rinses, Inhibition of Sweet Taste by Naproxen Oral Rinses
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Oct 21, 2026, 1:43 PM EDT
Terminated Phase 4 Interventional Results available

IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia

NCT01200069
View directory record Official record
Conditions
Depression, Myalgia
Interventions
Placebo infusion, ibuprofen intravenous
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 21, 2026, 1:43 PM EDT
Recruiting Phase 2 Interventional

Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

NCT04676802
View directory record Official record
Conditions
Pain, Postoperative, Osteoarthritis Thumb
Interventions
NSAID capsules, Opioid capsule
Drug
Lead sponsor
Stanford University
Other
Eligibility
45 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Redwood City, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myogenic and Osteogenic Responses to eXercise and Ibuprofen

NCT00462722
View directory record Official record
Conditions
Aging, Physical Fitness
Interventions
Ibuprofen, Placebo, musculoskeletal-loading exercise
Drug · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 75 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Oct 21, 2026, 1:43 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

NCT05721027
View directory record Official record
Conditions
Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
Interventions
Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
Drug · Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat

NCT06247462
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Ibuprofen 600 mg, Placebo Corn Starch
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances

NCT02272725
View directory record Official record
Conditions
Acute Kidney Injury, Exercise-associated Hyponatremia, Perceived Exertion
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Results available

Surgical Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen

NCT01334957
View directory record Official record
Conditions
Pain
Interventions
Intravenous ibuprofen
Drug
Lead sponsor
Cumberland Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
22
States / cities
La Jolla, California • Napa, California • Miami, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Pediatric Fracture Analgesia Study

NCT00520442
View directory record Official record
Conditions
Fracture
Interventions
ibuprofen, acetamin w codeine
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
4 Years to 18 Years
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 7, 2008 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants

NCT00728117
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
feeding, fasting
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
23 Weeks to 33 Weeks
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
14
States / cities
San Francisco, California • San Jose, California • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2012 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Results available

Acetaminophen (APAP) +/- Oxycodone

NCT04122443
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Acetaminophen, Oxycodone
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 21, 2026, 1:43 PM EDT
Recruiting No phase listed Observational

Postoperative Pain After Pediatric Adenotonsillectomy With Ketorolac or Ibuprofen

NCT07672418
View directory record Official record
Conditions
Sleep, Pediatrics, Adenotonsillectomy
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
13 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 1:43 PM EDT
Completed No phase listed Observational

Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants

NCT00795990
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 3 Months
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

Efficacy Of PF-05089771 In Treating Postoperative Dental Pain

NCT01529346
View directory record Official record
Conditions
Postoperative Dental Pain
Interventions
PF-05089771, Placebo, Ibuprofen
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 21, 2026, 1:43 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC Consumers

NCT03722238
View directory record Official record
Conditions
Pain
Interventions
Ibuprofen 600 mg Immediate Release/Extended Release Caplet
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Enrollment
613 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
27
States / cities
Hoover, Alabama • Mesa, Arizona • Tucson, Arizona + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 21, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage

NCT04447924
View directory record Official record
Conditions
Reduction of Small Intestinal Ulceration Risk
Interventions
Bif195, Placebo
Dietary Supplement · Other
Lead sponsor
Chr Hansen
Industry
Eligibility
18 Years to 40 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Oct 21, 2026, 1:43 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ibuprofen Versus Indomethacin Following Emergent Cerclage Placement

NCT04726085
View directory record Official record
Conditions
Preterm Labor
Interventions
Indomethacin 150mg, Ibuprofen 2400mg
Drug
Lead sponsor
Woman's
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 21, 2026, 1:43 PM EDT
Not yet recruiting Phase 4 Interventional

Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?

NCT06505148
View directory record Official record
Conditions
Pediatric Disorder
Interventions
Acetaminophen, Ibuprofen
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
3 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 21, 2026, 1:43 PM EDT