Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1801–1824 of 1,885 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Impaired Cognition Clear all

Conditions: Alzheimer Disease, Mild Cognitive Impairment, Long-Term Care Planning
Interventions: PlanYourLifespan.org; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 55 Years and older
Enrollment: 293 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Age-related Cognitive Decline
Interventions: Vortioxetine 10 mg, Cognitive training program; Drug · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 65 Years and older
Enrollment: 129 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Alcohol Use Disorder, Mild Cognitive Impairment, Transcranial Magnetic Stimulation
Interventions: Active, Open Label iTBS-rTMS; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 60 Years to 85 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Charleston, South Carolina

Conditions: Early Alzheimers Disease
Interventions: buntanetap/posiphen, Placebo; Drug
Lead sponsor: Annovis Bio Inc.; Industry
Eligibility: 55 Years to 85 Years
Enrollment: 760 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 78
States / cities: Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 72 more

Conditions: Advance Care Planning, Telemedicine, Mild Cognitive Impairment, Unrecognized Dementia, Dementia
Interventions: Telehealth visit; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years and older
Enrollment: 152 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 7
States / cities: Bermuda Run, North Carolina • Conover, North Carolina • High Point, North Carolina + 4 more

Conditions: Alzheimers Disease, Mild Cognitive Impairment
Interventions: 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation; Other
Lead sponsor: Emory University; Other
Eligibility: 50 Years to 90 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Eldery People, Cognitive Decline, Memory Decline, DHA CNS Delivery
Interventions: LPC-EPA+DHA capsules containing omega-3 fatty acids EPA and DHA esterified to lysophosphatidylcholine (LPC-EPA+DHA)(Trade name: Lysoveta); Dietary Supplement
Lead sponsor: University of Cincinnati; Other
Eligibility: 55 Years to 82 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Parkinson Disease
Interventions: GRF6021, Placebo; Drug · Other
Lead sponsor: Alkahest, Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 19
States / cities: Little Rock, Arkansas • Englewood, Colorado • Doral, Florida + 15 more

Conditions: Amnestic Mild Cognitive Impairment, Alzheimer's Disease
Interventions: Insulin (Humulin® R U-100), Placebo; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 55 Years to 85 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 25
States / cities: Phoenix, Arizona • Irvine, California • New Haven, Connecticut + 18 more

Conditions: Brain Cancer
Interventions: Virtual Reality System, Word Search Puzzles; Other
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cannabis Use, THC, Marijuana Use, Cognitive Impairment, THC Vaping
Interventions: 15% THC Potency Reduction, 35% THC Potency Reduction; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 25 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Mild Cognitive Impairment, Alzheimer's Disease
Interventions: FDG-PET, ASL-MRI, Lumbar Puncture; Drug · Other · Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 55 Years to 89 Years
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Dementia, Mild Cognitive Impairment
Interventions: Patient Priorities Care; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 40 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 3
States / cities: Indianapolis, Indiana • Houston, Texas

Conditions: Parkinson's Disease
Interventions: florbetapir F 18; Drug
Lead sponsor: Avid Radiopharmaceuticals; Industry
Eligibility: 60 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Dementia, Mild Cognitive Impairment
Interventions: Templated, clinician-facilitated intervention to align everyday living preferences assessment; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Midlife Obese Adults With Cognitive Decline
Interventions: Prolonged nightly fasting, Health Education Control; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 40 Years to 59 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
Interventions: Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC; Other · Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 50 Years to 90 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Medication Administered in Error, Cognitive Impairment
Interventions: Not listed
Lead sponsor: University of Rochester; Other
Eligibility: 65 Years and older
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Early Alzheimer's Disease
Interventions: Lecanemab IV, Placebo, Lecanemab SC; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 50 Years to 90 Years
Enrollment: 1,906 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 112
States / cities: Phoenix, Arizona • Sun City, Arizona • Tucson, Arizona + 82 more

Conditions: Aging, MCI
Interventions: MediTrain, Worder, noninvasive neurostimulation device, wrist worn multi-sensor watches; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 60 Years to 85 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Breast Cancer, Cognitive Impairment
Interventions: Not listed
Lead sponsor: Northwestern University; Other
Eligibility: 40 Years to 70 Years · Female only
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson's Disease
Interventions: Strattera, Exelon, Placebo; Drug · Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
Interventions: Robotic Exoskeleton Rehabilitation, Conventional Gait Therapy; Device · Other
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Alzheimer Disease
Interventions: Routine Care Documentation; Other
Lead sponsor: Alzheimer's Disease and Related Disorders Association, Inc; Other
Eligibility: 18 Years and older
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2032
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

Decision Making and Implementation of Aging-in-Place/Long Term Care Plans Among Older Adults

Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training

rTMS in Older Adults With MCI and AUD

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

A Telehealth Advance Care Planning Intervention in Those With Mild Cognitive Impairment or Unrecognized Dementia

Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease

Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia

A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors.

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

Arterial Spin Labeling (ASL) MRI for Cognitive Decline

Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia

Florbetapir F 18 PET Imaging of Beta-amyloid in Parkinson's Disease Patients

An Intervention to Reduce Discrepancy in Everyday Preferences

Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults

Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease

Screening and Interventions in an Acute Care Setting

A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation

Mild Cognitive Impairment in Breast Cancer Patients

Cognitive Decline in Non-demented PD

Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS

Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)