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ClinicalTrials.gov public records Last synced Jul 23, 2026, 9:48 PM EDT

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Showing 1–24 of 197 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Implant Failure Clear all
Terminated Phase 4 Interventional Results available

Nesiritide and Renal Function After the Total Artificial Heart

NCT01836809
View directory record Official record
Conditions
Congestive Heart Failure, Cardiorenal Syndrome
Interventions
nesiritide, placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Jul 23, 2026, 9:48 PM EDT
Terminated Not applicable Interventional

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

NCT06543446
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
ICD implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
3,290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Portland, Maine • Baltimore, Maryland • Boston, Massachusetts + 10 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 23, 2026, 9:48 PM EDT
Active, not recruiting Phase 3 Interventional

NOVOCART 3D Treatment Following Microfracture Failure

NCT03219307
View directory record Official record
Conditions
Articular Cartilage Defect
Interventions
NOVOCART 3D
Combination Product
Lead sponsor
Aesculap Biologics, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
3
States / cities
Chicago, Illinois • Columbus, Ohio • North Logan, Utah
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jul 23, 2026, 9:48 PM EDT
Terminated No phase listed Observational

Recovery of Hibernating Myocardium in End Stage Heart Failure

NCT02573207
View directory record Official record
Conditions
Myocardial Function After LVAD Implant, Ischemic Cardiomyopathy
Interventions
Not listed
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Phase 3 Interventional Results available

Ranolazine Implantable Cardioverter-Defibrillator Trial

NCT01215253
View directory record Official record
Conditions
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
Interventions
Ranolazine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
83
States / cities
Tucson, Arizona • Little Rock, Arkansas • East Palo Alto, California + 70 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Diagnostic Investigation of Sudden Cardiac Event Risk

NCT00500708
View directory record Official record
Conditions
Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Anchorage, Alaska • Palo Alto, California • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Phase 1 Interventional

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

NCT00573560
View directory record Official record
Conditions
Heart Failure
Interventions
VPD Implant System
Device
Lead sponsor
CardioKinetix, Inc
Industry
Eligibility
18 Years to 74 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Asheville, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Jul 23, 2026, 9:48 PM EDT
Not listed Not applicable Interventional

Frozen Blastocyst Transfer Using Conventional Timing Versus Timing by Endometrial Receptivity Analysis

NCT03558399
View directory record Official record
Conditions
Implantation Failure, Infertility, Female
Interventions
FET according to ERA, FET according to standard protocol
Other
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
30 Years to 40 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

Chronicle Offers Management to Patients With Advanced Signs and Symptoms of Heart Failure (COMPASS-HF)

NCT00643279
View directory record Official record
Conditions
Heart Failure
Interventions
Chronicle Implantable Hemodynamic Monitor, Standard of Care
Device · Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
28
States / cities
Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 22 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Jul 23, 2026, 9:48 PM EDT
Terminated Phase 4 Interventional

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

NCT00370526
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement
Procedure
Lead sponsor
Stereotaxis
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
3
States / cities
Gainesville, Georgia • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 10, 2008 · Synced Jul 23, 2026, 9:48 PM EDT
Withdrawn Early Phase 1 Interventional

Placement of CS/LV Pacing Leads With EnSite NavX Guidance

NCT00577187
View directory record Official record
Conditions
Heart Failure
Interventions
EnSite NavX-Guided CRT implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Use of Defibrillator Information in the Emergency Department

NCT00708058
View directory record Official record
Conditions
Congestive Heart Failure, Medical Device
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Not applicable Interventional

The Fluoroless-CSP Trial Using Electroanatomic Mapping

NCT03903107
View directory record Official record
Conditions
Sinus Node Dysfunction, Heart Block AV, LBBB, Heart Failure, Systolic
Interventions
Conventional fluoroscopy guided Conduction System Pacing(CSP), Electroanatomic Mapping (Fluoroless) guided Conduction System Pacing(CSP)
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

NCT03015194
View directory record Official record
Conditions
Mitral Valve Failure
Interventions
Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational Results available

Continuous Cardiac Arrhythmia Monitoring in Hemodialysis Patients

NCT00932659
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
continuous cardiac monitoring device (REVEAL, Medtronic)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2013 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

RAPID-RF: Remote Active Monitoring in Patients With Heart Failure

NCT00334451
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
891 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2014 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms

NCT00916435
View directory record Official record
Conditions
Congestive Heart Failure, Sudden Cardiac Death, Arrhythmia, Cardiomyopathies
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Jul 23, 2026, 9:48 PM EDT
Terminated Not applicable Interventional Results available

Evaluation of Anti-platelet Factor 4/Heparin Antibodies in Hemodialysis Patients

NCT02165761
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
GORE® Hybrid Vascular Graft, Non-heparin bonded synthetic graft
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Hackensack, New Jersey • Charlotte, North Carolina • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Arteriovenous Fistula Tissue Bank for Pre- and Post-Fistula Placement Specimens

NCT00836862
View directory record Official record
Conditions
Kidney Failure, Chronic
Interventions
Biologic specimens
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Jul 23, 2026, 9:48 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Phrenic Nerve Stimulation for Treatment of Central Sleep Apnea

NCT03238937
View directory record Official record
Conditions
Sleep Apnea, Central, Heart Failure
Interventions
Phrenic nerve stimulator
Device
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Jul 23, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation

NCT02111993
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure, Cardiac Arrhythmia
Interventions
Standard Defibrillation Testing, Upper Limit of Vulnerability Testing
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Jul 23, 2026, 9:48 PM EDT
Completed No phase listed Observational

Right Ventricular Failure After Implantation of Left Ventricular Assist Devices

NCT01999712
View directory record Official record
Conditions
Heart Failure
Interventions
Echocardiography
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced Jul 23, 2026, 9:48 PM EDT
Not listed Phase 1 Interventional

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

NCT00050765
View directory record Official record
Conditions
Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions
MyoCell™ Autologous Myoblasts
Drug
Lead sponsor
Bioheart, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
5
States / cities
Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2006 · Synced Jul 23, 2026, 9:48 PM EDT