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ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:40 AM EST

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Showing 1–24 of 162 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Implantable Cardiac Defibrillators Clear all

Conditions: Cardiac Implantable Electronic Device Infection
Interventions: Not listed
Lead sponsor: TYRX, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,262 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 52
States / cities: Birmingham, Alabama • Decatur, Alabama • Florence, Alabama + 44 more

Conditions: Magnetic Resonance Imaging
Interventions: ImageReady MR Conditional Defibrillation System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 34
States / cities: Huntsville, Alabama • Jonesboro, Arkansas • Pasadena, California + 31 more

Conditions: Ventricular Arrhythmias
Interventions: Implantation of subcutaneous ICD, Implantation of transvenous ICD; Device
Lead sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Other
Eligibility: 18 Years and older
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2023
U.S. locations: 10
States / cities: New Haven, Connecticut • Atlanta, Georgia • Chicago, Illinois + 4 more

Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: ICD implantation; Procedure
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 3,290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 13
States / cities: Portland, Maine • Baltimore, Maryland • Boston, Massachusetts + 10 more

Conditions: Left Ventricular Systolic Dysfunction, Sudden Cardiac Death
Interventions: regadenoson; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Heart Failure, Obesity
Interventions: Body Composition Analysis InBody Scale; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tachycardia, Diabetes Mellitus, Cardiovascular Disease
Interventions: Subcutaneous Implantable Cardioverter Defibrillator; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 65 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 36
States / cities: Huntsville, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 31 more

Conditions: Heart Arrest, Implantable Defibrillator User, Physical Activity
Interventions: E-ICD Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Ventricular Tachycardia (VT)
Interventions: Sphere-9 Catheter with the Affera Mapping and Ablation System; Device
Lead sponsor: Medtronic Cardiac Ablation Solutions; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 6
States / cities: Boston, Massachusetts • New York, New York • Cleveland, Ohio + 3 more

Conditions: Tachycardia
Interventions: OVATIO DR 6550; Device
Lead sponsor: LivaNova; Industry
Eligibility: 18 Years and older
Enrollment: 462 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 5
States / cities: Atlanta, Georgia • Decatur, Georgia • Mandeville, Louisiana + 2 more

Conditions: Arrhythmias, Cardiac
Interventions: MRI Scan; Device
Lead sponsor: Essentia Health; Other
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Duluth, Minnesota

Conditions: Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
Interventions: Not listed
Lead sponsor: CardioDx; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 1,564 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 8
States / cities: Anchorage, Alaska • Palo Alto, California • Minneapolis, Minnesota + 5 more

Conditions: Anxiety
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: Not listed
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Coronary Artery Disease
Interventions: ICD; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 17
States / cities: Anchorage, Alaska • Brandon, Florida • Orlando, Florida + 14 more

Conditions: Congestive Heart Failure
Interventions: Paradym CRT + Physiological Diagnosis (PhD); Device
Lead sponsor: ELA Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Heart Failure, Systolic
Interventions: Exercise-similar cardiac pacing, Sham cardiac pacing; Device
Lead sponsor: Denice Hodgson-Zingman, MD; Other
Eligibility: 18 Years to 120 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Atrial Fibrillation
Interventions: Internal Cardioversion, External Cardioversion; Procedure
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 99 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Arrhythmia
Interventions: Intervention; Behavioral
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 3
States / cities: Aurora, Colorado • Lone Tree, Colorado • Greenville, North Carolina

Conditions: Heart Failure
Interventions: Automated HF/EP Referral, Placebo (Registry Arm); Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Pacemaker, Implantable Defibrillator
Interventions: Alert-based care, Guideline-based Care; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure, Hypertension
Interventions: Not listed
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Imperial, California

Conditions: Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation
Interventions: Cardiac Resynchronization Therapy+Implantable Cardioverter Defibrillator; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 30
States / cities: Anchorage, Alaska • Phoenix, Arizona • Santa Monica, California + 27 more

Conditions: Cardiac Arrhythmia
Interventions: Pacemaker, ICD, or CRT device; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 58
States / cities: Scottsdale, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 55 more

Conditions: Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases, Implantable Cardioverter Defibrillator
Interventions: Azimilide Dihydrochloride, Placebo; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 83
States / cities: Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 72 more

Search by objective public record fields.

TYRX™ Envelope for Prevention of Infection Following Replacement With a CRT or ICD

ENABLE MRI (Magnetic Resonance Imaging)

A PRospective, rAndomizEd Comparison of subcuTaneOous and tRansvenous ImplANtable Cardioverter Defibrillator Therapy

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

Heart Rate Response to Regadenoson and Sudden Cardiac Death

Safety of Body Composition Analysis in Heart Failure Patients With Implantable Cardioverter Defibrillators (ICDs)

Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator

Effectiveness of Exercise After an ICD

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications

Study to Monitor Patients With Pacemakers or ICDs Who Undergo MRI Scans

Diagnostic Investigation of Sudden Cardiac Event Risk

Interventional Study of Anxiety Symptoms in the Implantable Cardioverter Defibrillator (ICD) Patient

ST Segment Detection Study

Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device

Paced Heart Rate Acceleration for Cardiac Conditioning

The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation

Establishing a Standard for Peri-operative Implantable Cardioverter Defibrillator (ICD) Patient Education

Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF)

Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices: The RAPTOR-CIED Study (Main Phase)

Necklace-Shaped Sensor for Non-Invasive Remote Monitoring of Vitals

Clinical Investigation of the Medtronic Concerto™ Device

SJM MRI Diagnostic Imaging Registry (IDE)

Efficacy and Safety Study of Azimilide on the Incidence of Cardiovascular Hospitalizations/Emergency Department Visits or Cardiovascular Death in Patients With an Implantable Cardioverter Defibrillator (ICD) (SHIELD-2)