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ClinicalTrials.gov public records Last synced Oct 31, 2026, 7:56 AM EDT

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Showing 1–24 of 194 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Implantable Cardioverter Defibrillator Clear all
Terminated No phase listed Observational Results available

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

NCT05704426
View directory record Official record
Conditions
Atrial Fibrillation, Arrythmia
Interventions
Impulse Dynamics Optimizer Device
Device
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Diagnostic Investigation of Sudden Cardiac Event Risk

NCT00500708
View directory record Official record
Conditions
Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Anchorage, Alaska • Palo Alto, California • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Implantable Cardioverter Defibrillator (ICD) Function During Ventricular Assist Device (VAD) Implantation

NCT01576562
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Oct 31, 2026, 7:56 AM EDT
Active, not recruiting No phase listed Observational

PRE-DETERMINE Cohort Study

NCT01114269
View directory record Official record
Conditions
Coronary Artery Disease, Left Ventricular Dysfunction, Sudden Cardiac Death
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
5,764 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
86
States / cities
Anchorage, Alaska • Glendale, Arizona • Phoenix, Arizona + 76 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Air Pollution and Implantable Cardioverter Defibrillators

NCT00015574
View directory record Official record
Conditions
Arrythmias
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
0 Years to 90 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2006 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

iPod and Other MP3 Players on ICDs and Pacemakers in Children

NCT00542854
View directory record Official record
Conditions
Heart Block, Bradycardia, Tachycardia, Arrhythmia
Interventions
MP3
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2009 · Synced Oct 31, 2026, 7:56 AM EDT
Not listed No phase listed Observational

Electrophysiologic and Morphologic Assessment of the Substrate to Guide Implantation of Defibrillators in Dilated Cardiomyopathy

NCT01378572
View directory record Official record
Conditions
Dilated Cardiomyopathy, Primary Prevention of Sudden Cardiac Death, Implantable Cardioverter Defibrillator
Interventions
Not listed
Lead sponsor
Catholic University of the Sacred Heart
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Oct 31, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Effectiveness of Exercise After an ICD

NCT03544489
View directory record Official record
Conditions
Heart Arrest, Implantable Defibrillator User, Physical Activity
Interventions
E-ICD Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional

Clinical Investigation of the Medtronic Concerto™ Device

NCT00268320
View directory record Official record
Conditions
Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation
Interventions
Cardiac Resynchronization Therapy+Implantable Cardioverter Defibrillator
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
30
States / cities
Anchorage, Alaska • Phoenix, Arizona • Santa Monica, California + 27 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2008 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Enhancing Knowledge Implantable Cardioverter-Defibrillators (ICDs)

NCT00822965
View directory record Official record
Conditions
Pacemaker, Implantable Cardioverter-Defibrillators
Interventions
Questionnaires, Phone Interviews, Educational Packet
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Phase 3 Interventional Results available

Ranolazine Implantable Cardioverter-Defibrillator Trial

NCT01215253
View directory record Official record
Conditions
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
Interventions
Ranolazine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
83
States / cities
Tucson, Arizona • Little Rock, Arkansas • East Palo Alto, California + 70 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional

Improvement in Clinical Outcomes in Heart Failure Patients With ICDs That Practice Meditation

NCT00611260
View directory record Official record
Conditions
Congestive Heart Failure, Cardiac Resynchronization Therapy
Interventions
Vipassana Meditation practice and instruction, Standard Medical Care
Behavioral · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators

NCT03374891
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure
Interventions
Educational video and/or handout
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
790 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 31, 2026, 7:56 AM EDT
Not listed No phase listed Observational

CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy: an International Registry (DERIVATE)

NCT03352648
View directory record Official record
Conditions
Heart Failure, Left Ventricular Systolic Dysfunction
Interventions
Not listed
Lead sponsor
Gianluca Pontone, MD, PhD
Other
Eligibility
Not listed
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
2
States / cities
Chicago, Illinois • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 31, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

NCT06703489
View directory record Official record
Conditions
Ventricular Tachycardia (VT)
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Phase 2 Interventional Results available

Pilot Randomized Trial With Flecainide in ARVC Patients

NCT03685149
View directory record Official record
Conditions
Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions
Flecainide Pill, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
6
States / cities
Denver, Colorado • Baltimore, Maryland • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational Results available

Registry of Patients for MRI With Non-MRI Conditional Pacemakers and ICD Non-MRI Conditional Pacemakers and ICD

NCT02318550
View directory record Official record
Conditions
MRI Scans, Magnetic Resonance Imaging, Pacemaker, Implantable Cardioverter Defibrillator
Interventions
MRI Scan
Other
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 31, 2026, 7:56 AM EDT
Enrolling by invitation No phase listed Observational

IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

NCT04520347
View directory record Official record
Conditions
Ventricular Arrhythmia, Ventricular Tachycardia, Premature Ventricular Contraction (PVC), Cardiomyopathy
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
34
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 25 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional Results available

ZIPS Study - Zip Incision aPproximation vs. Suture

NCT02213510
View directory record Official record
Conditions
Wound, Cardiac Arrhythmia
Interventions
Zip Surgical Skin Closure Device, Standard Suture Closure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 30, 2016 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Risk of Life-threatening Heart Rhythm Disturbances in Siblings

NCT00498524
View directory record Official record
Conditions
Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
Interventions
ICD
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2,047 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 7, 2012 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional Results available

A Clinical Evaluation of the Durata or Optisure High Voltage Leads and Ellipse VR ICD Undergoing MRI, an IDE Study

NCT02787291
View directory record Official record
Conditions
Implantable Defibrillator User
Interventions
Ellipse VR ICD and Durata/Optisure lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
26
States / cities
Phoenix, Arizona • Bakersfield, California • La Jolla, California + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 31, 2026, 7:56 AM EDT
Completed No phase listed Observational

Safety of Magnetic Resonance Imaging in Patients With Pacemakers and Defibrillators

NCT02227004
View directory record Official record
Conditions
Conditions Requiring Diagnostic Evaluation
Interventions
Perform MRI in patients with pacemaker or ICD
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 100 Years
Enrollment
1,275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 31, 2026, 7:56 AM EDT
Recruiting Not applicable Interventional

Paced Heart Rate Acceleration for Cardiac Conditioning

NCT06332391
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Exercise-similar cardiac pacing, Sham cardiac pacing
Device
Lead sponsor
Denice Hodgson-Zingman, MD
Other
Eligibility
18 Years to 120 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 31, 2026, 7:56 AM EDT
Completed Not applicable Interventional Results available

Remote Device Interrogation In The Emergency Department

NCT01871090
View directory record Official record
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Zanesville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 31, 2026, 7:56 AM EDT