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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:02 PM EDT

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Showing 97–120 of 189 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Implantable Cardioverter Defibrillator Implanted Clear all
Completed No phase listed Observational

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation

NCT03164395
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Internal Cardioversion, External Cardioversion
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Syngery-Evaluating the Impact of Decision Aid

NCT03832868
View directory record Official record
Conditions
Implantable Cardioverter-defibrillators (ICDs)
Interventions
Pre-visit timing of receipt of the ICDs implantation decision aid, Post-visit timing of receipt of the ICDs implantation decision aid
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation

NCT02111993
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure, Cardiac Arrhythmia
Interventions
Standard Defibrillation Testing, Upper Limit of Vulnerability Testing
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 9, 2026, 5:02 PM EDT
Terminated Not applicable Interventional Results available

Pediatric Lead Extractability and Survival Evaluation (PLEASE)

NCT00335036
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy, Long QT Syndrome, Congenital Heart Disease
Interventions
ICD lead implant, Thin leads
Device
Lead sponsor
Charles Berul
Other
Eligibility
1 Year to 55 Years
Enrollment
748 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting Phase 4 Interventional

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

NCT06964464
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death, Ventricular Arrhythmia, Implantable Cardioverter Defibrillator (ICD), Beta-blocker Therapy, Cardiomyopathy
Interventions
Metoprolol Succinate, Carvedilol
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
13
States / cities
Scottsdale, Arizona • Rome, Georgia • Shawnee Mission, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Sleep and Ventricular Arrhythmias Study

NCT02232204
View directory record Official record
Conditions
Cardiac Arrhythmia, Implantable Defibrillator User, Insomnia
Interventions
CBT for Insomnia in ICD Patients (CBT-I-ICD)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 5, 2014 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational Results available

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

NCT00395447
View directory record Official record
Conditions
Device Replacement, Elective Replacement (ERI), Device Advisory, Device Upgrade, Postoperative Complications
Interventions
Straight-forward Device Replacement, Device Replacement with Upgrade
Procedure
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
71
States / cities
Birmingham, Alabama • Mesa, Arizona • Modesto, California + 58 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational

Patient Expectations After Implantable-cardioverter Defibrillator (ICD) Implantation

NCT00845390
View directory record Official record
Conditions
Defibrillators, Implantable
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational

Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy

NCT03884608
View directory record Official record
Conditions
Cardiomyopathies, Gender, Implantable Defibrillator User
Interventions
Not listed
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
49
States / cities
Birmingham, Alabama • Fairhope, Alabama • Rancho Mirage, California + 41 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator (ICD) Interventions or Death

NCT00993382
View directory record Official record
Conditions
Arrhythmia Prophylaxis, Ventricular Arrhythmia
Interventions
Celivarone, Amiodarone, Matching placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
21 Years and older
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
37
States / cities
Huntsville, Alabama • Mobile, Alabama • Mesa, Arizona + 33 more
Source: ClinicalTrials.gov public record
Updated May 30, 2016 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational

Safety of Magnetic Resonance Imaging in Patients With Pacemakers and Defibrillators

NCT02227004
View directory record Official record
Conditions
Conditions Requiring Diagnostic Evaluation
Interventions
Perform MRI in patients with pacemaker or ICD
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 100 Years
Enrollment
1,275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

NCT00305240
View directory record Official record
Conditions
Myocardial Infarction, Arrhythmia, Ventricular, Ischemic Cardiomyopathy
Interventions
T Wave Alternans Test
Procedure
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
656 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
47
States / cities
Mobile, Alabama • Phoenix, Arizona • Walnut Creek, California + 44 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2008 · Synced Oct 9, 2026, 5:02 PM EDT
Terminated Not applicable Interventional

Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF)

NCT01807130
View directory record Official record
Conditions
Heart Failure
Interventions
Automated HF/EP Referral, Placebo (Registry Arm)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 9, 2026, 5:02 PM EDT
Withdrawn Not applicable Interventional

Dance4Healing: Explore the Benefits of Tele-Dance in Individuals with an Implantable Cardioverter-defibrillator (ICD)

NCT04678128
View directory record Official record
Conditions
ICD, Anxiety, Patient Engagement
Interventions
Dance4Healing Telehealth Live Zoom Sessions, Dance Buddy
Behavioral
Lead sponsor
Sanjiv Narayan, MD, PhD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational

Sensing Atrial High Rate Episodes With Implantable Cardioverter-Defibrillators Trial (The SENSE Trial)

NCT02186704
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ICD with DX system
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
8
States / cities
Birmingham, Alabama • Boston, Massachusetts • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Enrolling by invitation No phase listed Observational

IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

NCT04520347
View directory record Official record
Conditions
Ventricular Arrhythmia, Ventricular Tachycardia, Premature Ventricular Contraction (PVC), Cardiomyopathy
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
34
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 25 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 2 Interventional Results available

Pilot Randomized Trial With Flecainide in ARVC Patients

NCT03685149
View directory record Official record
Conditions
Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions
Flecainide Pill, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
6
States / cities
Denver, Colorado • Baltimore, Maryland • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting No phase listed Observational

Ambulatory Surgical Center Implantable Cardioverter-Defibrillator Outcomes Registry

NCT03604133
View directory record Official record
Conditions
Arrhythmia
Interventions
Not listed
Lead sponsor
QuesGen Systems Inc
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 9, 2026, 5:02 PM EDT
Withdrawn Not applicable Interventional

Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing

NCT00585871
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
clonidine, metoprolol
Drug
Lead sponsor
James Martins
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational

TRENDS: A Prospective Study of the Clinical Significance of Atrial Arrhythmias Detected by Implanted Device Diagnostics

NCT00279981
View directory record Official record
Conditions
Atrial Fibrillation, Stroke, Heart Failure
Interventions
Diagnostic
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
92
States / cities
Mesa, Arizona • Tucson, Arizona • Fountain Valley, California + 89 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2008 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational Results available

TYRX™ Envelope for Prevention of Infection Following Replacement With a CRT or ICD

NCT01043705
View directory record Official record
Conditions
Cardiac Implantable Electronic Device Infection
Interventions
Not listed
Lead sponsor
TYRX, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
52
States / cities
Birmingham, Alabama • Decatur, Alabama • Florence, Alabama + 44 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2015 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Comparison of VF Induction Techniques During Medtronic ICD Implant (VF) (ICD)

NCT02027883
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Nominal T shock setting, Educated T shock setting
Device
Lead sponsor
James Merrill
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase 1 Trial to Determine Dosimetry, Biodistribution and Safety of LMI 1195-101 in Healthy Subjects and Patients With Heart Failure

NCT00891241
View directory record Official record
Conditions
Heart Failure
Interventions
LMI 1195-101
Drug
Lead sponsor
Lantheus Medical Imaging
Industry
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
2
States / cities
Hartford, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 9, 2026, 5:02 PM EDT