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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:56 AM EDT

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Showing 337–360 of 600 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Incision Clear all
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

NCT04331080
View directory record Official record
Conditions
Mammoplasty, Scarring, Scar, Breast Reconstruction
Interventions
Granexin® gel 100 μM, Granexin® gel 200 μM, Vehicle gel
Drug
Lead sponsor
Xequel Bio, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
11
States / cities
Los Angeles, California • Pasadena, California • Doral, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional

Effect of Mupirocin Dressings Versus Island Dressings on Surgical Site Infections in Elective Colorectal Surgery

NCT02619773
View directory record Official record
Conditions
Surgical Site Infections
Interventions
mupirocin ointment
Procedure
Lead sponsor
Gundersen Lutheran Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 17, 2026, 11:56 AM EDT
Recruiting No phase listed Observational

Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

NCT06378359
View directory record Official record
Conditions
Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
Interventions
Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening, Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening., Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 17, 2026, 11:56 AM EDT
Not yet recruiting Not applicable Interventional

Use of Fish Skin Graft (FSG) to Improve Wound Healing and Expedite Discharge at a County Safety-net Hospital

NCT06910189
View directory record Official record
Conditions
Surgical Wound
Interventions
Fish Skin Graft (FSG), Wound Vacuum-Assisted Closure (VAC)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity

NCT00603603
View directory record Official record
Conditions
Infection; Cesarean Section, Surgical Wound Infection, Endometritis
Interventions
80% inhaled oxygen via non-rebreather mask, 30% inhaled oxygen via nasal cannula
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 50 Years · Female only
Enrollment
606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2016 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Skin Incision Adhesive in Pediatrics

NCT01514396
View directory record Official record
Conditions
Wounds
Interventions
Surgiseal
Device
Lead sponsor
Medline Industries
Industry
Eligibility
5 Years to 18 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Loop Drainage Versus Incision and Drainage for Abscesses in Children

NCT02443272
View directory record Official record
Conditions
Abscess of Skin and/or Subcutaneous Tissue
Interventions
Vessel Loop Drainage, Incision and Drainage
Procedure
Lead sponsor
Seton Healthcare Family
Other
Eligibility
29 Days to 17 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 17, 2026, 11:56 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Deep Lamellar Endothelial Keratoplasty: Small Incision Technique

NCT00345020
View directory record Official record
Conditions
Corneal Transplantation
Interventions
Deep Lamellar Endothelial Keratoplasty: Small Incision Technique
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Phase 4 Interventional Results available

PAIN - Postoperative Analgesia INvestigation

NCT02111746
View directory record Official record
Conditions
Postoperative Pain
Interventions
Exparel, Bupivacaine hydrochloride, Patient Controlled Analgesia (PCA)
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 17, 2026, 11:56 AM EDT
Terminated Not applicable Interventional Results available

Evaluation of a Novel Post-Surgical Dressing

NCT01831596
View directory record Official record
Conditions
Post Surgical Wound
Interventions
ciSNaP
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 17, 2026, 11:56 AM EDT
Terminated Not applicable Interventional Results available

Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients

NCT00315822
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
80% oxygen, 30% oxygen
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Louisville, Kentucky • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 17, 2026, 11:56 AM EDT
Terminated No phase listed Observational

Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections / Standard Care Change

NCT01148030
View directory record Official record
Conditions
Surgical Site Infection
Interventions
3M Skin and Nasal Antiseptic
Drug
Lead sponsor
3M
Industry
Eligibility
2 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days

NCT05559697
View directory record Official record
Conditions
Skin Reaction to Mechanical, Thermal and Radiation Stimuli, Skin Sensitisation
Interventions
Sponsor incisional negative pressure wound therapy device and dressing, Standard of Care incisional negative pressure wound therapy system
Device
Lead sponsor
DeRoyal Industries, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 17, 2026, 11:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Replacing Buried Sutures With Tissue Adhesive on Aesthetic Outcome of Surgical Wounds.

NCT03425370
View directory record Official record
Conditions
Surgical Wound
Interventions
Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 2, 2018 · Synced Oct 17, 2026, 11:56 AM EDT
Terminated No phase listed Observational

Incisions for Cardiac Surgery

NCT00229892
View directory record Official record
Conditions
Cardiac Surgery, Cardiac Diseases
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2011 · Synced Oct 17, 2026, 11:56 AM EDT
Recruiting Not applicable Interventional

NPWT Reduction Mammaplasty

NCT06725459
View directory record Official record
Conditions
Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions
Prophylactic ciNPWT, Standard Adhesive Dressing
Device · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty

NCT01037985
View directory record Official record
Conditions
Scar Prevention
Interventions
EXC 001, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 45 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
6
States / cities
La Jolla, California • Chicago, Illinois • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery

NCT01297959
View directory record Official record
Conditions
Infections
Interventions
E-101 Solution 300 GU/ml, Saline solution
Drug
Lead sponsor
Excited States, LLC
Industry
Eligibility
18 Years and older
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
34
States / cities
Mobile, Alabama • Los Angeles, California • Stanford, California + 29 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Oct 17, 2026, 11:56 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

NCT04072289
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Visumax spherocylindrical treatment
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Performance and Safety of ConvaFoam™ Silicone, ConvaFoam™ Border and ConvaFoam™ Non-Adhesive Dressings in the Management of Surgical and Traumatic Wounds

NCT05632276
View directory record Official record
Conditions
Surgical Wound, Trauma-related Wound
Interventions
ConvaFoam
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

NCT01656044
View directory record Official record
Conditions
Colon Cancer, Pancreatic Cancer, Perioperative/Postoperative Complications, Primary Peritoneal Cavity Cancer, Rectal Cancer
Interventions
wound care management
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional

One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection

NCT02734134
View directory record Official record
Conditions
Surgical Site Infection
Interventions
One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • New York, New York • Charlotte, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 11:56 AM EDT
Completed No phase listed Observational Results available

Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry Eye

NCT01161771
View directory record Official record
Conditions
Dry Eye
Interventions
Cataract Surgery and Limbal relaxing incision
Procedure
Lead sponsor
Allergan
Industry
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Long Island City, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2012 · Synced Oct 17, 2026, 11:56 AM EDT
Completed Not applicable Interventional

Glioma Supra Marginal Incision Trial

NCT04737577
View directory record Official record
Conditions
High Grade Glioma
Interventions
Supramarginal resection, Conventional (i.e. GTR) resection
Procedure
Lead sponsor
Sunnybrook Health Sciences Centre
Other
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 17, 2026, 11:56 AM EDT