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ClinicalTrials.gov public records Last synced Nov 5, 2026, 9:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Incisional Pain Clear all

Conditions: Liver and Intrahepatic Bile Duct Disorder
Interventions: Bupivacaine, Fentanyl, Hydromorphone Hydrochloride, Implanted Medical Device, Liposomal Bupivacaine, Questionnaire; Drug · Device · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Abscess, Pain
Interventions: Intranasal Fentanyl, Intravenous Morphine; Drug
Lead sponsor: Columbia University; Other
Eligibility: 4 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Operative Pain, Appendicitis
Interventions: Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic, Post-Closure Saline; Drug · Other
Lead sponsor: Valley Anesthesiology Consultants; Other
Eligibility: 9 Years to 17 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst, Apical Granuloma, Periradicular Disease, Previous Endodontic Treatment
Interventions: PBM treatment, PBM sham treatment, EMS; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Surgical Incision, Pain, Postoperative, Pain, Acute
Interventions: Bupivacaine 0.25%, Normal Saline; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Pain, Postoperative
Interventions: control group, treatment group; Drug
Lead sponsor: Mihaela Visoiu; Other
Eligibility: 8 Years to 17 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions: Transabdominal Plane Block, Non Transabdominal Plane Block; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 127 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Stress Urinary Incontinence, Surgical Incision, Pain Vulva
Interventions: Bupivacaine-Meloxicam; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Pain, Postoperative
Interventions: Ketolorac; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 90 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Beachwood, Ohio

Conditions: Postherpetic Neuralgia
Interventions: Civamide Patch; Drug
Lead sponsor: Winston Laboratories; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 3
States / cities: Sunrise, Florida • Chicago, Illinois • Ann Arbor, Michigan

Conditions: Abscess, Pain
Interventions: intranasal ketamine, intranasal fentanyl, intranasal midazolam; Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 3 Years to 17 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Post-operative Pain, Cesarean Section
Interventions: ON-Q Pump® with continuous infusion of bupivacaine, ON-Q Pump® with continuous infusion of saline; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Pain, Postoperative
Interventions: Trans-incisional rectus sheath block, Laparoscopic guided rectus sheath block, Ropivacaine; Procedure · Drug
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 10 Years to 21 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Hip Dysplasia
Interventions: Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline); Combination Product
Lead sponsor: Michael C Willey; Other
Eligibility: 13 Years to 50 Years
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Ventral Hernia, Incisional Hernia
Interventions: Mesh placement with Transfascial Sutures; Procedure
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Incisional Pain
Interventions: TAP Catheter and Infusion of Study Solution; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases, Musculoskeletal Diseases, Edema Leg, Joint Pain, Arthritis Knee
Interventions: Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 22 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 6
States / cities: Annapolis, Maryland • Baltimore, Maryland • Columbia, Maryland + 3 more

Conditions: Surgery, Pain, Postoperative, Incision, Otolaryngological Disease
Interventions: Smartphone, Virtual Reality (Oculus Quest); Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
Interventions: Silver-impregnated dressing, Telfa pad dressing; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Female only
Enrollment: 660 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 3
States / cities: Tampa, Florida

Conditions: Pain, Inflammation
Interventions: Anakinra, Normal Saline; Drug · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Stanford, California

Conditions: Pain, Postoperative, Irritation (Physical), Pelvic Pain
Interventions: Vicryl Suture, Dermabond; Procedure
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Pain, Postoperative, Morbid Obesity
Interventions: Injected bupivacaine post-operatively, Streamed bupivacaine versus streamed normal saline, Aerosolized bupivacaine versus aerosolized saline, Injected lidocaine pre-incision vs saline pre-incision; Drug
Lead sponsor: Pinnacle Health System; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Harrisburg, Pennsylvania

Conditions: Hysterotomy Closure
Interventions: Stratafix synthetic barbed suture; Procedure
Lead sponsor: Evangelical Community Hospital, Lewisburg, PA; Other
Eligibility: 16 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Lewisburg, Pennsylvania

Conditions: Pain, Postoperative, Femur Fracture
Interventions: Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Search by objective public record fields.

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children

Evaluation of Local Anesthetic at Incision Site

Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery

Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision

Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery

Ketolorac Versus Saline at Laparoscopic Incision Sites

Evaluation of Civamide Patch in Treatment of Postherpetic Neuralgia and Post-Incisional Neuralgia

IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D

Post-operative Cesarean Trial of Pain Control

Trans-incisional vs Laparoscopic Guided Rectus Sheath Block for Pediatric Single Incision Laparoscopic Cholecystectomy

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation

Continuous Transversus Abdominis Plane Nerve Block for Postoperative Analgesia

Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA

Virtual Reality for Postoperative Pain Management

Prospective Study on Cesarean Wound Outcomes

Immunomodulation, IL-1 Inhibition, and Postoperative Incisional Pain

Comparison of Skin Incision Closure Material for the Transobturator Suburethral Sling Procedure

Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic

Study to Compare Suture Material in Closure of Uterine Incision in Cesarian Section

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures