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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:33 AM EDT

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Showing 265–288 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Infant,Premature Clear all
Completed Not applicable Interventional

A Pilot Study Comparing Telehealth and In-Person Therapy Service Delivery Following NICU Discharge

NCT06893003
View directory record Official record
Conditions
Prematurity Complications, NICU Infants, Early Intervention, Telehealth
Interventions
Baby Bridge
Other
Lead sponsor
University of Southern California
Other
Eligibility
Up to 6 Months
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional

NEO Rehab for Infants at Risk of Cerebral Palsy

NCT03372590
View directory record Official record
Conditions
Prematurity, Cerebral Palsy
Interventions
NICU-based rehabilitation bundle, Standard of care
Other
Lead sponsor
University of Virginia
Other
Eligibility
Up to 33 Weeks
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Cold Liquids Fed to Preterm Infants: Efficacy and Safety After 10 Minutes of Exposure

NCT02935946
View directory record Official record
Conditions
Deglutition Disorders, Respiratory Aspiration
Interventions
Cold Liquid Barium
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
36 Weeks to 43 Weeks
Enrollment
4,043 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Oct 21, 2026, 6:33 AM EDT
Active, not recruiting Phase 2 Interventional

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

NCT03253263
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage, Retinopathy of Prematurity (ROP)
Interventions
OHB-607
Drug
Lead sponsor
OHB Neonatology Ltd.
Industry
Eligibility
0 Hours to 24 Hours
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
24
States / cities
Little Rock, Arkansas • California City, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Not yet recruiting Phase 1 Interventional

Breast-milk Enema Administration to Stimulate Passage of Meconium

NCT07661992
View directory record Official record
Conditions
Breast-milk
Interventions
breast milk
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Phase 4 Interventional Results available

Preterm Infant Inhaled Albuterol Dosing

NCT02447250
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Very Low Birth Weight
Interventions
Varied albuterol dose response
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
14 Days and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Spinal Stimulation and Mobility Devices

NCT05520359
View directory record Official record
Conditions
Cerebral Palsy, Stroke, Premature Birth, Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia
Interventions
Mobility Device, Spinal Stimulation
Device
Lead sponsor
University of Washington
Other
Eligibility
4 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Active, not recruiting Not applicable Interventional

PREEMIE: Study for Treatment of PDA in Premature Infants

NCT06587282
View directory record Official record
Conditions
Patent Ductus Arteriosus (PDA)
Interventions
Bloom Micro Occluder System
Device
Lead sponsor
Merit Medical Systems, Inc.
Industry
Eligibility
5 Days and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
9
States / cities
Sacramento, California • San Diego, California • Hollywood, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Active, not recruiting Not applicable Interventional Results available

Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk

NCT04325308
View directory record Official record
Conditions
Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure, Microbial Colonization
Interventions
Protein-enriched human milk diet, Usual human milk diet
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 4 Days
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Enrolling by invitation Not applicable Interventional

Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

NCT07176117
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Surfactant
Interventions
Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA), Continuous Positive Airway Pressure (CPAP)
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
33 Weeks to 38 Weeks
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
3
States / cities
Chula Vista, California • La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Completed No phase listed Observational

Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

NCT03277768
View directory record Official record
Conditions
Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability
Interventions
Resonance Raman Spectroscopy (RRS)
Device
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Enrollment
55 participants
Timeline
2015 – 2018
U.S. locations
2
States / cities
Gainesville, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring the Feasibility of Centering Pregnancy With Care Navigation

NCT05645549
View directory record Official record
Conditions
Premature Birth
Interventions
Centering Pregnancy with Care Navigation
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Phase 3 Interventional

Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight

NCT00114543
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Aggressive Phototherapy 501-750g, Aggressive Phototherapy 751-1000g, Conservative Phototherapy 501-750g, Conservative Phototherapy 751-1000g
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 36 Hours
Enrollment
1,974 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Relationship Between EIT and Respiratory Status in Very Preterm Infants

NCT06609135
View directory record Official record
Conditions
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
Interventions
Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
Device
Lead sponsor
Lawrence Rhein
Other
Eligibility
5 Days and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome

NCT00957840
View directory record Official record
Conditions
Intraventricular Hemorrhage, Premature Infants
Interventions
NIRS, aEEG, and CSF concentration of biomarkers
Procedure
Lead sponsor
University of Utah
Other
Eligibility
Up to 1 Year
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

IV Acetaminophen and Patent Ductus Arteriosus

NCT03008876
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Acetaminophen, Ibuprofen
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
1 Minute to 2 Weeks
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Oct 21, 2026, 6:33 AM EDT
Not listed Phase 2 Interventional

Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.

NCT01268215
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Infasurf, Pulmicort, Sham
Drug · Other
Lead sponsor
East Carolina University
Other
Eligibility
24 Weeks to 28 Weeks
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Phase 1Phase 2 Interventional

Effects of Massage on the Immune System of Preterm Infants

NCT00317278
View directory record Official record
Conditions
Premature Birth, Stress
Interventions
massage therapy, Sham
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
28 Weeks to 33 Weeks
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2009 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

NCT04154423
View directory record Official record
Conditions
Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety, Depression, Postpartum, Satisfaction, Patient, Health Problems in Pregnancy
Interventions
Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Female only
Enrollment
678 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Fresno, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 6:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Work of Breathing in Premature Infants at Discharge

NCT03682575
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Very Low Birth Weight Infant, Prematurity
Interventions
Enrollment
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
1 Month to 7 Months
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)

NCT01030575
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Bronchopulmonary Dysplasia (BPD)
Interventions
Inositol lower volume, Inositol mid-level volume, Inositol high volume, Placebo low volume
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 72 Hours
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Oct 21, 2026, 6:33 AM EDT
Withdrawn Phase 2 Interventional

Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity (BLOCK-ROP)

NCT01232777
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Bevacizumab
Drug
Lead sponsor
Vision Research Foundation
Other
Eligibility
30 Weeks to 36 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
18
States / cities
Los Angeles, California • Palo Alto, California • Miami, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2013 · Synced Oct 21, 2026, 6:33 AM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control: Role in Respiratory Outcomes

NCT03174301
View directory record Official record
Conditions
Infant, Premature
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
Up to 1 Week
Enrollment
739 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Oct 21, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Treatment of Cranial Molding Deformities in Preterm Infants

NCT02366936
View directory record Official record
Conditions
Preterm Infants, Dolichocephaly, Positional Scaphocephaly
Interventions
Tortle Midliner
Device
Lead sponsor
Duke University
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 21, 2026, 6:33 AM EDT