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Showing 1009–1032 of 3,541 matching trials from the live ClinicalTrials.gov search.
Conditions
Rotavirus Infection, Rotavirus Vaccines
Interventions
Rotarix, Pediarix, Hiberix, Prevenar 13
Biological
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
6 Weeks to 12 Weeks
Enrollment
1,280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
47
States / cities
Birmingham, Alabama • Fayetteville, Arkansas • Jonesboro, Arkansas + 40 more
Conditions
Cystic Fibrosis
Interventions
Hyperpolarized Xenon
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

NCT06373289
Conditions
Bronchopulmonary Dysplasia, Pulmonary Hypertension
Interventions
higher oxygen saturation target using Nellcor pulse oximetry sensors, lower oxygen saturation target using Nellcor pulse oximetry sensors
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Month to 5 Months
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Birmingham, Alabama • New Haven, Connecticut
Completed No phase listed Observational Accepts healthy volunteers

Nuclear Morphology of Breast Cells in Ductal Lavage

NCT00259597
Conditions
Benign Breast Disease
Interventions
breast ductal lavage
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
HIV Infections, Pregnancy
Interventions
Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Day to 60 Years
Enrollment
1,496 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1994
U.S. locations
58
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 32 more
Conditions
Apnea of Prematurity
Interventions
Caffeine Citrate, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
29 Weeks to 33 Weeks
Enrollment
827 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
16
States / cities
Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 12 more
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Extubation to Nasal IPPV
Other
Lead sponsor
University of Southern California
Other
Eligibility
10 Minutes to 120 Minutes
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
4
States / cities
Los Angeles, California • San Diego, California • Augusta, Georgia + 1 more
Completed Not applicable Interventional Results available

Ultrasound Assisted Lumbar Puncture in the Neonate

NCT02918149
Conditions
Lumbar Puncture
Interventions
Palpation Landmark Technique, Ultrasound-Assisted Technique LP
Other · Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Phase 2 Interventional

Bevacizumab Treatment For Type 1 ROP

NCT04634578
Conditions
Retinopathy of Prematurity
Interventions
Bevacizumab
Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
Up to 6 Months
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
25
States / cities
Little Rock, Arkansas • Irvine, California • Los Angeles, California + 20 more
Conditions
Neonatal Respiratory Failure
Interventions
Standardized/structured CPAP weaning protocol
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
Up to 30 Weeks
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
5
States / cities
Escondido, California • La Jolla, California • Murrieta, California + 1 more
Conditions
Intestinal Failure, Rotavirus Vaccines
Interventions
Rotarix
Biological
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Weeks to 14 Weeks
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants

NCT03142568
Conditions
Bronchopulmonary Dysplasia
Interventions
Sildenafil, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Chicago, Illinois + 10 more
Completed Not applicable Interventional Results available

Cold Milk for Dysphagia in Preterm Infants

NCT04421482
Conditions
Dysphagia of Newborn
Interventions
Standard room temperature (RTS) feeding of milk/formula, Cold temperature (CS, at 4-9°C) of milk/formula
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Weeks and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Cystic Fibrosis
Interventions
Peripheral quantitative computed tomography (pQCT), Dual X-ray absorptiometry (DXA)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
6 Years to 12 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Little Rock, Arkansas
Completed Phase 1 Interventional Accepts healthy volunteers

Cotinine Metabolism in Infants and Children

NCT00994591
Conditions
Secondhand Smoke Exposure
Interventions
Pharmacokinetic dosing
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Months to 72 Months
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
San Francisco, California
Conditions
Single-ventricle
Interventions
Fortini formula, Standard Nutritional Care
Other
Lead sponsor
Driscoll Children's Hospital
Other
Eligibility
0 Months to 6 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Corpus Christi, Texas
Conditions
Primary Immune Deficiency
Interventions
Subcutaneous IgG (SCIG)
Biological
Lead sponsor
CSL Behring
Industry
Eligibility
Up to 2 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Los Angeles, California • Tampa, Florida • Plymouth, Minnesota + 2 more
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
6 Years to 99 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 15 more
Completed Not applicable Interventional Accepts healthy volunteers

Improving Lactation Success in Mothers of Critically Infants

NCT04097860
Conditions
Breast Pumping
Interventions
Text message including biomarker of breast pumping adequacy
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

NICU Asthma Education and Secondhand Smoke Reduction Study

NCT00499915
Conditions
Respiratory Illness
Interventions
Secondhand Smoke Reduction and Smoking Cessation Counseling, Asthma Education
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
Not listed
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2015
U.S. locations
1
States / cities
Rochester, New York
Not yet recruiting Not applicable Interventional

Rethinking Early Airway Clearence Therapies

NCT07696338
Conditions
Cystic Fibrosis (CF)
Interventions
As-needed hypertonic saline (HS), Twice daily hypertonic saline (HS), As-needed dornase alfa (DA), Daily dornase alfa (DA)
Other
Lead sponsor
Nicole Hamblett
Other
Eligibility
3 Years to 16 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
36
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 32 more
Conditions
Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Interventions
Not listed
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
30 Weeks to 83 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Talk With Me Baby to Enhance the Early Home Language Environment

NCT06479278
Conditions
Language Development, Speech, Infant Development, Infant Behavior, Language, Child, Language
Interventions
Talk with Me Baby
Behavioral
Lead sponsor
IDeA States Pediatric Clinical Trials Network
Network
Eligibility
0 Months to 9 Months
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Kansas City, Kansas • Morgantown, West Virginia
Conditions
Sickle Cell Anemia
Interventions
Hydroxyurea
Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
9 Months to 36 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Atlanta, Georgia • Jackson, Mississippi • Memphis, Tennessee + 1 more