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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Infertility,Male Clear all
Suspended Not applicable Interventional Accepts healthy volunteers

In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization

NCT00867763
View directory record Official record
Conditions
Infertility
Interventions
In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
Procedure
Lead sponsor
Batzofin Fertility Services
Other
Eligibility
21 Years to 41 Years · Female only
Enrollment
1,440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2010 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection

NCT00114725
View directory record Official record
Conditions
Infertility, Infertility, Male
Interventions
Laser-assisted intracytoplasmic sperm injection
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Ablation of Prostate Tissue Utilizing Sterile Water Vapor in Patients With Intermediate Risk Localized Prostate Cancer

NCT04087980
View directory record Official record
Conditions
Prostate Cancer
Interventions
Poseidon System
Device
Lead sponsor
Francis Medical Inc.
Industry
Eligibility
45 Years to 80 Years · Male only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Baltimore, Maryland • Minneapolis, Minnesota • Woodbury, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Jul 24, 2026, 2:05 AM EDT
Active, not recruiting No phase listed Observational

Developmental Epidemiological Study of Children Born Through Reproductive Technology

NCT03799107
View directory record Official record
Conditions
Infertility, Infertility, Female, Infertility, Male, Infertility Primary, Infertility Secondary, Infertility Unexplained
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
4 Years and older
Enrollment
3,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 24, 2026, 2:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Expanding Fertility Care to Poor and Low Resourced Settings Study

NCT05205733
View directory record Official record
Conditions
Healthy, Male Infertility, Infertility, Male, Fertility Disorders
Interventions
Mail-in semen analysis kit
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Jul 24, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Testicular Tissue Cryopreservation in Children

NCT02872532
View directory record Official record
Conditions
Cancer, Cancer-Related Condition, Infertility
Interventions
Testicular tissue cryopreservation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
0 Years to 17 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sperm Selection by Microfluidic Separation Improves Embryo Quality

NCT03085433
View directory record Official record
Conditions
Sperm DNA Fragmentation, Embryo Quality, Fertility Disorders, Infertility, Infertility, Male, Infertility Unexplained
Interventions
Microfluidic Sperm Sorting, in vitro fertilization
Device · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Assess the Bioequivalence of Follitropin Alfa Solution in Pen and Follitropin Alfa Powder in Vial in Healthy Downregulated Male Participants

NCT07097259
View directory record Official record
Conditions
Hypogonadism
Interventions
Test: Follitropin alfa, Reference: Follitropin alfa, Zoladex
Combination Product · Drug
Lead sponsor
EMD Serono Research & Development Institute, Inc.
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 24, 2026, 2:05 AM EDT
Completed No phase listed Observational

Hormonal Regulation of Puberty and Fertility

NCT01511588
View directory record Official record
Conditions
Endocrine Disease, Infertility, Hypogonadism, Amenorrhea, Adolescents
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
14 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 24, 2026, 2:05 AM EDT
Active, not recruiting No phase listed Observational

SpermQT Prospective Observational Trial

NCT05966883
View directory record Official record
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
Inherent Biosciences
Industry
Eligibility
18 Years to 45 Years
Enrollment
1,000 participants
Timeline
2023 – 2026
U.S. locations
6
States / cities
San Diego, California • Greenwood Village, Colorado • Orange, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jul 24, 2026, 2:05 AM EDT
Not listed Phase 2 Interventional

Pulsatile GnRH in Anovulatory Infertility

NCT00383656
View directory record Official record
Conditions
Hypogonadotropic Hypogonadism, Amenorrhea, Kallmann's Syndrome
Interventions
GnRH, Pump
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Jul 24, 2026, 2:05 AM EDT
Completed No phase listed Observational Results available

Impact of Sperm DNA Integrity on In Vitro Cycles

NCT01232465
View directory record Official record
Conditions
Male Infertility, Unexplained Infertility, Abortion, Habitual
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
Male only
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2014 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Andrositol® TEST as Diagnostic Assay to Predict the Fertilization Potential in IVF

NCT03677011
View directory record Official record
Conditions
Male Infertility
Interventions
Andrositol® Test
Diagnostic Test
Lead sponsor
Lo.Li.Pharma s.r.l
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Jul 24, 2026, 2:05 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

PET-MRI for Functional Imaging of the Testis: A Feasibility Study

NCT02669108
View directory record Official record
Conditions
Infertility, Non-obstructive Azoospermia, Vasectomy
Interventions
PET/ MRI of the Testis
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Phase 2 Interventional Results available

Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration

NCT01880086
View directory record Official record
Conditions
Hypogonadism, Opioid-Related Disorders, Male Infertility
Interventions
Clomiphene citrate, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Jul 24, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence

NCT07062237
View directory record Official record
Conditions
Infertility, Male Factor Infertility
Interventions
Ultrashort abstinence, Standard abstinence
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 42 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 24, 2026, 2:05 AM EDT
Not listed No phase listed Observational

Vitamin D and Human Sperm DNA Fragmentation

NCT03829943
View directory record Official record
Conditions
Infertility,Male, Vitamin D Deficiency
Interventions
Vitamin D
Diagnostic Test
Lead sponsor
Sanford Health
Other
Eligibility
21 Years to 56 Years · Male only
Enrollment
230 participants
Timeline
2019 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women

NCT00413179
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility, Hyperandrogenism
Interventions
Metformin, Clomiphene citrate, Placebo
Drug
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 40 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2003
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2006 · Synced Jul 24, 2026, 2:05 AM EDT
Completed No phase listed Observational

The Clinical Study of Sex Chromosome Variants

NCT01661010
View directory record Official record
Conditions
Male Factor Infertility, Female Factor Infertility
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 24, 2026, 2:05 AM EDT
Completed No phase listed Observational

Correlating In Vitro Fertilization Outcomes After Euploid Blastocyst Transfer With Sperm DNA Fragmentation

NCT02268123
View directory record Official record
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
35 Years to 40 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Basking Ridge, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 24, 2026, 2:05 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

GnRH Agonist at Embryo Transfer: IVF Outcomes

NCT03544073
View directory record Official record
Conditions
Infertility, Infertility, Female, Infertility, Male
Interventions
Saline Solution for Injection, Leuprolide Acetate
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jul 24, 2026, 2:05 AM EDT
Completed No phase listed Observational

Sperm Banking Among Adolescents Newly Diagnosed With Cancer: Development of a Profiling and Referral Tool

NCT01152268
View directory record Official record
Conditions
Cancer
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 21 Years · Male only
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Duarte, California • Los Angeles, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Jul 24, 2026, 2:05 AM EDT
Not listed Not applicable Interventional

Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive Azoospermia

NCT02851966
View directory record Official record
Conditions
Non-obstructive Azoospermia
Interventions
mTESE
Procedure
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
San Francisco, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Jul 24, 2026, 2:05 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Duloxetine on Male Fertility

NCT03038867
View directory record Official record
Conditions
Infertility, Male, Depression
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Jul 24, 2026, 2:05 AM EDT