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ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 769–792 of 1,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injuries, Craniocerebral Clear all
Terminated Phase 1 Interventional Accepts healthy volunteers

Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

NCT01939769
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Exercise - Low-intensity exercise, Exercise - High-intensity exercise
Other
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 45 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 25, 2026, 9:48 AM EDT
Terminated Phase 2 Interventional Results available

Sphenopalatine Ganglion Block for Headache After Concussion

NCT04650282
View directory record Official record
Conditions
Concussion, Headache
Interventions
Lidocaine in SphenoCath device, Saline Solution in SphenoCath device
Combination Product
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational

Minimally Invasive Dental Occlusion Ties

NCT04985461
View directory record Official record
Conditions
Jaw Fractures, Jaw; Fracture, Upper Jaw, Mandibular Fractures, Maxilla Fracture, Jaw Fixation
Interventions
dental occlusion ties maxillo-mandibular fixation
Device
Lead sponsor
Altru Health System
Other
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 25, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional

Mild TBI Assessment & Rehabilitation

NCT02920788
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Goal-Oriented Attentional Self-Regulation (GOALS), Brain Health Education (BHE), fMRI
Behavioral · Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 25, 2026, 9:48 AM EDT
Active, not recruiting No phase listed Observational

Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion

NCT04582682
View directory record Official record
Conditions
Concussion, Mild
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
5 Years to 24 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Syracuse, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational Results available

Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury

NCT00676182
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Telerehabilitation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 25, 2016 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Pre-Military Life Experiences/Exposures on Active-Duty Service Members' Psychological Health

NCT06070025
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Oceanside, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational

Evaluation of Outcomes Related to Cerebrospinal Fluid Drain Placement

NCT04505423
View directory record Official record
Conditions
Cerebrospinal Fluid Drainage
Interventions
Blind CSF Drain Placement, Fluoroscopy-guided Drain Placement
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC

NCT01214694
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT), Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express), Internet Resources Comparison (IRC)
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 9 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
5
States / cities
Aurora, Colorado • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Oct 25, 2026, 9:48 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Exercise and Rehabilitation After Traumatic Brain Injury

NCT03407924
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Aerobic Exercise (AER), Rehabilitation
Other
Lead sponsor
Centre for Neuro Skills
Industry
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion

NCT02750566
View directory record Official record
Conditions
Post-Concussion Symptoms, Distorted; Balance
Interventions
Osteopathic Manipulative Treatment, Counseling
Procedure · Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department

NCT02882256
View directory record Official record
Conditions
Urinary Tract Infection, Head Injury, Laceration
Interventions
Video discharge instructions
Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 25, 2026, 9:48 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Cortical Excitability in Post-traumatic Epilepsy

NCT05517954
View directory record Official record
Conditions
Traumatic Brain Injury, Cortical Excitability, Epilepsy
Interventions
Not listed
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional

The Effects of Playing Live Music in Music Therapy/Occupational Therapy Co-treatment on Unilateral Spatial Neglect

NCT02919722
View directory record Official record
Conditions
Unilateral Spatial Neglect (USN)
Interventions
Music Therapy
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Phase 4 Interventional Results available

Simvastatin for mTBI

NCT01952288
View directory record Official record
Conditions
TBI-Traumatic Brain Injury
Interventions
simvastatin, Placebo Oral Tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 25, 2026, 9:48 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Heart Rate Variability Biofeedback Following Traumatic Brain Injury

NCT05913505
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
OSC-
Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional Results available

Enhanced Problem-Solving Training

NCT03759223
View directory record Official record
Conditions
Brain Concussion
Interventions
Enhanced Problem-Solving Training (E-PST), Healthy Living Messages (HLM), Enhanced Problem-Solving Training (E-PST) (non-randomized)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Video Review of the Frequency and Assessment of Head Impacts During the FIFA World Cup 2022TM

NCT05629169
View directory record Official record
Conditions
Head Injury, Concussion, Brain Injuries, Traumatic Brain Injury
Interventions
No intervention applied - observational study only
Other
Lead sponsor
Federation Internationale de Football Association
Other
Eligibility
Male only
Enrollment
832 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational

Testing Devices That Involve the Sense of Touch in Subjects With Traumatic Brain Injury

NCT01404494
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional Results available

Brain Training to Enhance Frontal Lobe Reasoning

NCT01552473
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Brain Training Program 1, Brain Training Program 2
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
19 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 25, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional

Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation

NCT06589362
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcutaneous auricular vagus active nerve stimulation, Transcutaneous auricular vagus sham nerve stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 25, 2026, 9:48 AM EDT
Enrolling by invitation Not applicable Interventional

Investigation of Neurocognitive Measures of Sport-Related Injury

NCT03414242
View directory record Official record
Conditions
Concussion, Brain
Interventions
Cervical spine musculature
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 30 Years
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 25, 2026, 9:48 AM EDT
Completed No phase listed Observational

Pilot Study of NeuroTriage Device in Patients with Potential Brain Injury And/or Impairment

NCT03761641
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Neurotriage
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 25, 2026, 9:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Comparison for Undergraduate College Students With Traumatic Brain Injury

NCT04628741
View directory record Official record
Conditions
Traumatic Brain Injury, Concussion, Brain
Interventions
Dynamic Coaching Model, Apprenticeship Approach
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 25, 2026, 9:48 AM EDT