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ClinicalTrials.gov public records Last synced Nov 1, 2026, 2:28 AM EST

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Showing 1273–1296 of 1,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injuries, Craniocerebral Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Rural Veterans With Post-traumatic Stress Disorder (PTSD) And Comorbid Mild Traumatic Brain Injury (TBI): A Feasibility Study

NCT01278316
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Traumatic Brain Injury
Interventions
Control, Cognitive Training
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
20 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Nov 1, 2026, 2:28 AM EST
Completed Not applicable Interventional

Comparative Utility of Clinical Balance Measures in Traumatic Brain Injury

NCT02696538
View directory record Official record
Conditions
Traumatic Brain Injury, Acquired Brain Injury, Accidental Falls
Interventions
Functional Gait Assessment, mini-Balance Evaluation Systems Test, Berg Balance Scale
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Nov 1, 2026, 2:28 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Anticipatory and Compensatory Postural Responses to Avoid Falls After TBI

NCT05268484
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Perturbation-based Training with visual cues using Neurocom
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Nov 1, 2026, 2:28 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Prevention of Shaken Baby Syndrome

NCT00105963
View directory record Official record
Conditions
Child Abuse, Shaken Baby Syndrome
Interventions
Education about infant crying
Behavioral
Lead sponsor
Harborview Injury Prevention and Research Center
Other
Eligibility
1 Day to 4 Weeks
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Nov 1, 2026, 2:28 AM EST
Completed Not applicable Interventional Results available

Effects of LEDs on Memory in TBI Patients

NCT01598532
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
MedX Health Phototherapy (light therapy)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Nov 1, 2026, 2:28 AM EST
Terminated Early Phase 1 Interventional

Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA

NCT03241719
View directory record Official record
Conditions
Amputation, Traumatic, Amputation;Traumatic;Old, Face Injury, Face; Deformity, Abdominal Wall Defect
Interventions
IL-2
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Nov 1, 2026, 2:28 AM EST
Recruiting Not applicable Interventional

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

NCT07116109
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Direct Current Stimulation (tDCS), Massed-Prolonged Exposure (PE), Sham Transcranial Direct Current Stimulation (tDCS)
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Nov 1, 2026, 2:28 AM EST
Completed Not applicable Interventional

Restoration of Life Role Participation Through Cognitive and Motor Training for TBI

NCT01158781
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Experimental: gait, balance, arm function, cognition
Behavioral
Lead sponsor
Malcom Randall VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Nov 1, 2026, 2:28 AM EST
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury

NCT02613936
View directory record Official record
Conditions
Traumatic Brain Injury, Post Concussive Symptoms, Depression, Executive Dysfunction
Interventions
Anodal tDCS, Cognitive training
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Nov 1, 2026, 2:28 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Mayo Clinic Traumatic Brain Injury Model System Center: The CONNECT Trial

NCT02088099
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Complex clinical intervention, Treatment as usual
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Nov 1, 2026, 2:28 AM EST
Recruiting Phase 2 Interventional

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

NCT05951777
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Autologous HB-adMSCs, Normal Saline
Biological · Drug
Lead sponsor
Hope Biosciences LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Nov 1, 2026, 2:28 AM EST
Withdrawn Not applicable Interventional

Non-invasive Intracranial Pressure (ICP) Monitoring in Pediatric Patients

NCT02695264
View directory record Official record
Conditions
Intracranial Hypertension
Interventions
HS-1000 recording
Device
Lead sponsor
HeadSense Medical
Industry
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2016 · Synced Nov 1, 2026, 2:28 AM EST
Completed No phase listed Observational

Approaches and Decisions for Acute Pediatric TBI Trial

NCT04077411
View directory record Official record
Conditions
Severe Traumatic Brain Injury
Interventions
Observational
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 18 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 25 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2023 · Synced Nov 1, 2026, 2:28 AM EST
Recruiting Not applicable Interventional

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

NCT05663034
View directory record Official record
Conditions
Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress, Sleep, Memory Impairment, Cognitive Behavioral Therapy, Concussion, Brain, Head Injury, Brain Injury Traumatic Mild
Interventions
Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Eglin Air Force Base, Florida • Bethesda, Maryland • Fort Bragg, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Nov 1, 2026, 2:28 AM EST
Completed Phase 2 Interventional Results available

Brain Tissue Oxygen Monitoring in Traumatic Brain Injury (TBI)

NCT00974259
View directory record Official record
Conditions
Severe Traumatic Brain Injury
Interventions
Management protocol based on pBrO2 and ICP values., Management protocol based on ICP values only.
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
10
States / cities
Miami, Florida • Durham, North Carolina • Cincinnati, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Nov 1, 2026, 2:28 AM EST
Terminated Phase 3 Interventional Results available

Study of Citicoline for the Treatment of Traumatic Brain Injury (COBRIT)

NCT00545662
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Placebo, citicoline
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years
Enrollment
1,213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Birmingham, Alabama • Baltimore, Maryland • Philadelphia, Pennsylvania + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Nov 1, 2026, 2:28 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

An Evaluation of HS-1000 Device Capabilities in the Diagnosis and Assessment of Patients After Concussion

NCT02699346
View directory record Official record
Conditions
Brain Concussion, Brain Injuries
Interventions
HS-1000 recording
Device
Lead sponsor
HeadSense Medical
Industry
Eligibility
13 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 22, 2016 · Synced Nov 1, 2026, 2:28 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Advanced MRI Applications for Mild Traumatic Brain Injury

NCT02070588
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Traumatic Brain Injury
Interventions
MRI
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
15 Years to 50 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Nov 1, 2026, 2:28 AM EST
Completed No phase listed Observational Accepts healthy volunteers Results available

Traumatic Brain Injury (TBI) Screening Instruments

NCT00875329
View directory record Official record
Conditions
Brain Injury
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2015 · Synced Nov 1, 2026, 2:28 AM EST
Not yet recruiting No phase listed Observational

Deployment of a Novel National Institute of Neurological Disorders and Stroke Clinical, Biomarker, Imaging, and Modifiers (CBI-M) Classification Framework for Emergency Department Patients With Glasgow Coma Scale 15 Traumatic Brain Injury (PIONEER-Prognosis)

NCT07858266
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Torrance, California • Ann Arbor, Michigan • Clinton Township, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 1, 2026, 2:28 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Dynamic Vision Testing and Concussion Management

NCT04837066
View directory record Official record
Conditions
Head Injury, Sport Injury, Concussion, Brain
Interventions
Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
Diagnostic Test
Lead sponsor
California State University, Northridge
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Northridge, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Nov 1, 2026, 2:28 AM EST
Recruiting Not applicable Interventional

Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics

NCT05566431
View directory record Official record
Conditions
Severe Traumatic Brain Injury
Interventions
ICP, CREVICE
Other
Lead sponsor
University of Washington
Other
Eligibility
1 Year to 12 Years
Enrollment
428 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Nov 1, 2026, 2:28 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Using Virtual Technologies to Prevent Injuries in Adolescents With Acquired Brain Injury

NCT04768946
View directory record Official record
Conditions
Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
12 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2022 · Synced Nov 1, 2026, 2:28 AM EST
Completed Phase 1 Interventional

Online Emotional Regulation Group Treatment

NCT01730261
View directory record Official record
Conditions
Traumatic Brain Injury, Executive Dysfunction, Emotional Dysregulation
Interventions
Online Emotional Regulation Treatment
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Nov 1, 2026, 2:28 AM EST