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ClinicalTrials.gov public records Last synced Nov 13, 2026, 5:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 992 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Insomnia Disorders Clear all

Conditions: Sleep, Wearable Technology, Cortisol, Healthy Participants, Cognitive Abilities
Interventions: PeptiSleep, Micro-crystalline cellulose; Dietary Supplement
Lead sponsor: Nuritas Ltd; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Transient Insomnia
Interventions: Gabapentin, Placebo; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 773 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 10
States / cities: San Diego, California • Ocala, Florida • Atlanta, Georgia + 6 more

Conditions: Epilepsy, Sleep
Interventions: Lemborexant, Placebo; Drug
Lead sponsor: University of Manitoba; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Older Adults (65 Years and Older)
Interventions: Cognitive-behavioral therapy for insomnia, Sleep hygiene education; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Insomnia
Interventions: Ramelteon, Usual Care; Drug · Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: CNS
Interventions: E2006, Placebo comparator; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Culver City, California • Glendale, California

Conditions: Insomnia
Interventions: Internet-based Self-help Insomnia Intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
Interventions: The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:; Drug
Lead sponsor: Duke University; Other
Eligibility: 0 Years to 20 Years
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 49
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 40 more

Conditions: Chronic Pain, Insomnia, HIV
Interventions: Brief Behavioral Treatment for Insomnia (BBTI), Brief Mindfulness Training (BMT); Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 25 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hypertension, Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral
Lead sponsor: Duke University; Other
Eligibility: 30 Years to 60 Years
Enrollment: 149 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Suicide, Depression, Anxiety, Insomnia, Agitation
Interventions: Alpha-Stim®., Montgomery-Åsberg Depression Rating Scale, Hamilton Anxiety Rating Scale, The Pittsburgh Sleep Quality Index and agitated behavior Scale; Device · Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Insomnia, Depression
Interventions: Digital CBT-I, Digital SHE; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 456 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Diabetes, Prediabetic, Prediabetes, Glucose Intolerance
Interventions: eszopiclone; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 64 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alzheimer's Disease, Insomnia
Interventions: quetiapine; Drug
Lead sponsor: University of Vermont; Other
Eligibility: 55 Years to 90 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Insomnia
Interventions: supported digital CBTI, digital CBTI; Behavioral · Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: Insomnia Disorder
Interventions: education and coaching on developing healthy nighttime sleep and daytime activity behaviors; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Insomnia
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 29
States / cities: Birmingham, Alabama • Jasper, Alabama • Mesa, Arizona + 26 more

Conditions: Insomnia, Sleeplessness, Transient Insomnia
Interventions: Electric stimulation of the Vestibular Nerve - "VirtuSom", Electric stim of the Vestibular Nerve - "VirtuSom" - SHAM; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 50 Years
Enrollment: 349 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 6
States / cities: Atlanta, Georgia • New York, New York • Rochester, New York + 2 more

Conditions: Hematopoietic Stem Cell Transplant
Interventions: Cognitive behavioral therapy for insomnia (CBT-I); Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Chronic Insomnia, Primary Insomnia
Interventions: Mindfulness-Based Stress Reduction, eszopiclone; Behavioral · Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 2
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Use, Tobacco Cessation, Insomnia
Interventions: Experimental health intervention, Varenicline; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Insomnia
Interventions: Mindfulness-based therapy for insomnia (MBTI), Healthy lifestyle intervention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 25 Years to 45 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Orange, Connecticut

Conditions: Insomnia, Fibromyalgia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Pain (CBT-P); Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Traumatic Brain Injury, Anxiety
Interventions: Not listed
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

Effects of PeptiSleep on Sleep Quality in Healthy Adults

A Study of Single-Dose Gabapentin in Subjects With Transient Insomnia Induced by a Sleep Phase Advance

Lemborexant Treatment of Insomnia Linked to Epilepsy

CBT-I in Older African American Adults

Ramelteon for Complex Insomnia in Veterans With PTSD

2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain

Sleep Quality and Mechanisms of Cardiovascular Risks in Adults With Hypertension

Cranial Electric Stimulation to Modify Suicide Risk Factors in Psychiatric Inpatients.

Perinatal Research on Improving Sleep and Mental Health

Sleep Effectiveness and Insulin and Glucose Homeostasis

Quetiapine for the Treatment of Insomnia in Alzheimer's Disease

Clinician Training Program to Integrate Digital CBTI Into Routine Psychotherapy

Sleep Well 24 (SWELL24) Healthy Sleep-Wake Behaviors in Older Adults

Long-Term Efficacy of Ramelteon on Endocrine Function in Adult Subjects With Chronic Insomnia

Evaluation of Vestibular Stimulation to Help Occasional Sleeplessness

Early Cognitive Behavioral Therapy for Insomnia (CBT-I) in People Planning to Under Hematopoietic Stem Cell Transplant (HSCT)

Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Mindfulness Based Therapy for Insomnia in Black Women

Sleep and Pain Interventions in Fibromyalgia

Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury