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Showing 169–192 of 992 matching trials from the live ClinicalTrials.gov search.
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

NCT07288593
Conditions
Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions
NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment)
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 62 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Minneapolis, Minnesota
Completed Phase 4 Interventional Results available

The Treatment of Insomnia in Patients With HIV Disease

NCT00465972
Conditions
HIV Infections, Insomnia
Interventions
Doxepin, Temazepam, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 69 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels, Brain Fog, Mood Instability, Sleep Quality, Skin Clarity, Facial Puffiness, Bad Breath
Interventions
Super Liver
Dietary Supplement
Lead sponsor
SuperBonsai Inc.
Industry
Eligibility
30 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
Family Caregivers, Insomnia, Sleep Initiation and Maintenance Disorders
Interventions
SHUTi (Sleep Healthy Using the Internet)
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Charlottesville, Virginia
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation and Sleep

NCT04021537
Conditions
PTSD
Interventions
non-invasive nerve stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Results available

Blue Wavelength Light-blocking Glasses in ADHD-Insomnia

NCT01557595
Conditions
Attention Deficit Hyperactivity Disorder, Delayed Sleep Phase Type Circadian Rhythm Sleep Disorder
Interventions
Polarized glasses designed to filter out blue light
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Opioid Use Disorder, Opioid Use, Insomnia, Orexin Antagonist
Interventions
Placebo, Lemborexant 10 MG
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Sleep Problem, Insomnia, Pediatric Cancer
Interventions
Survivor-SHIP
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
5 Years to 12 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Insomnia
Interventions
Solriamfetol 75 MG, Cognitive Behavioral Therapy for Insomnia (CBT-I), Monitoring, Placebo
Drug · Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
25 Years to 60 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability Study of My Sleep Our Sleep (MSOS) Program

NCT04712604
Conditions
Insomnia
Interventions
My Sleep Our Sleep (MSOS) Program
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Effects of PeptiSleep on Sleep Quality in Healthy Adults

NCT07258433
Conditions
Sleep, Wearable Technology, Cortisol, Healthy Participants, Cognitive Abilities
Interventions
PeptiSleep, Micro-crystalline cellulose
Dietary Supplement
Lead sponsor
Nuritas Ltd
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Wilmington, Delaware
Conditions
Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia, Depressive Symptoms, Quality of Life, Psychological Flexibility, Sleep Quality, Positive Aspects of Caregiving
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Logan, Utah
Conditions
Insomnia, Fibromyalgia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Pain (CBT-P)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy, Hypnosis
Behavioral
Lead sponsor
Center for Trauma Recovery, St Louis
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Transient Insomnia
Interventions
Gabapentin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
773 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
10
States / cities
San Diego, California • Ocala, Florida • Atlanta, Georgia + 6 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Insomnia Disorder
Interventions
education and coaching on developing healthy nighttime sleep and daytime activity behaviors
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Chronic Insomnia, Primary Insomnia
Interventions
Mindfulness-Based Stress Reduction, eszopiclone
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Minneapolis, Minnesota
Conditions
Cough
Interventions
Agave Syrup
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
2 Months to 48 Months
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Conditions
Sleep Initiation and Maintenance Disorders, Suicidal Ideation
Interventions
Digital Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
MICHAEL A GRANDNER
Other
Eligibility
55 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Major Depressive Disorder, Insomnia
Interventions
SAGE-217, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 64 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Garden Grove, California + 24 more
Completed Not applicable Interventional Accepts healthy volunteers

Well-being Promotion and Sleep Hygiene Education to Improve Sleep Quality

NCT04316663
Conditions
Poor Quality Sleep
Interventions
Well-Being Intervention, Sleep Hygiene
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Sleep Deprivation
Interventions
Eye mask and ear plugs
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas