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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:12 AM EDT

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Showing 241–264 of 714 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Insulin Resistance Syndrome Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome

NCT00670800
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Metformin
Drug
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2014 · Synced Oct 12, 2026, 3:12 AM EDT
Recruiting Not applicable Interventional

A Study Of Milk Consumption In Metabolic Syndrome

NCT07401888
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Full-fat diet, Low-fat diet
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Phase 2 Interventional Results available

Oral Nitrite in Adults With Metabolic Syndrome and Hypertension

NCT01681810
View directory record Official record
Conditions
Metabolic Syndrome, Hypertension
Interventions
14Nitrogen Sodium Nitrite
Drug
Lead sponsor
Gladwin, Mark, MD
Individual
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Intervention for Visceral Adiposity

NCT01350518
View directory record Official record
Conditions
Obesity
Interventions
Benefiber, TrueLemon
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Results available

Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity

NCT02060279
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Lifestyle intervention and carotenoid supplements, Lifestyle intervention and placebo
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 11 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 12, 2026, 3:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Animal and Plant Proteins and Glucose Metabolism

NCT03994367
View directory record Official record
Conditions
Metabolic Syndrome, Metabolic Syndrome, Protection Against, Glucose Metabolism Disorders
Interventions
High animal protein isolate, High animal protein whole food, High plant protein isolate, High plant protein whole food
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Grains Reduce Adiposity and Improve Nutrition Study

NCT00924521
View directory record Official record
Conditions
Metabolic Syndrome, Insulin Resistance
Interventions
Whole grain diet, Refined grain
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
35 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 12, 2026, 3:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Personalized Moderate Intensity Exercise Training Combined With High Intensity Interval

NCT03568214
View directory record Official record
Conditions
Exercise, Metabolic Syndrome
Interventions
Exercise
Other
Lead sponsor
Western Colorado University
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gunnison, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 12, 2026, 3:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

NCT00690755
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-Centre Intervention Trial II

NCT02029833
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Metabolic Syndrome
Interventions
Regular Canola Oil, High Oleic Canola Oil, Western Type Diet - Common Dietary Oils
Other
Lead sponsor
University of Manitoba
Other
Eligibility
20 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2023 · Synced Oct 12, 2026, 3:12 AM EDT
Recruiting Phase 4 Interventional

LDL-C Optimization Using Inclisiran in Patients in Which Drug-Drug Interactions Limit LDL Lowering

NCT06865885
View directory record Official record
Conditions
Drug Interactions, Primary Prevention, Cardiometabolic Syndrome, LDL-Cholersterol Lowering
Interventions
Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 12, 2026, 3:12 AM EDT
Active, not recruiting Not applicable Interventional

Diet and Health in Adults With Metabolic Syndrome

NCT03935048
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Higher protein, low glycemic load diet
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 12, 2026, 3:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer

NCT02103140
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Facility-based Exercise, Home-based Exercise
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 12, 2026, 3:12 AM EDT
Terminated Phase 1 Interventional

Effect of Cinnamon Extract on Insulin Resistance in Polycystic Ovary Syndrome

NCT00970541
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Insulin Resistance
Interventions
Cinnamon Supplementation, Placebo (wheat flour)
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Exercise Dose-Response on Features of the Metabolic Syndrome

NCT00687128
View directory record Official record
Conditions
Insulin Resistance, Metabolic Syndrome, Obesity
Interventions
Low-intensity treadmill exercise, Moderate-intensity treadmill exercise, Non-aerobic stretching exercise
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 60 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2012 · Synced Oct 12, 2026, 3:12 AM EDT
Completed No phase listed Observational

Peds Metabolic Syndrome in Psoriasis

NCT00930592
View directory record Official record
Conditions
Psoriasis, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
10 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WALK Study: Women's Active Living for Koreans Study

NCT03681756
View directory record Official record
Conditions
Physical Activity, Metabolic Syndrome, Lifestyle, Sedentary
Interventions
WALK
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

AFTER: Altering Fat Through Estrogen and Raloxifene

NCT00149604
View directory record Official record
Conditions
Postmenopause
Interventions
conjugated estrogens, Raloxifene, exercise plus mild caloric restriction for weight loss
Drug · Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years to 70 Years · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 2, 2009 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional

Women's Lifestyle Balance Study

NCT03184337
View directory record Official record
Conditions
PreDiabetes, Metabolic Syndrome, Overweight
Interventions
CDC's PreventT2 Program, CDC's PreventT2 Program with Added Sleep Content
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 70 Years · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance

NCT00264251
View directory record Official record
Conditions
HIV Infections, Insulin Resistance, Obesity
Interventions
Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
Behavioral · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
20 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2007 · Synced Oct 12, 2026, 3:12 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Weight Loss Using a Feedback Device in Obese People With the Metabolic Syndrome

NCT03491930
View directory record Official record
Conditions
Weight Loss, Obesity, Pre-Diabetes, Metabolic Syndrome
Interventions
VA MOVE! Coach app, Telephone Coaching, Standard of Care for weight loss.
Device · Behavioral
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Oct 12, 2026, 3:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers Results available

The Safety and Efficacy Study of RiaGev in Healthy Adults

NCT04483011
View directory record Official record
Conditions
Metabolic Syndrome, Premature Aging
Interventions
RiaGev
Dietary Supplement
Lead sponsor
Bioenergy Life Science, Inc.
Industry
Eligibility
36 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 12, 2026, 3:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shift-and-persist and Cardiometabolic Markers Among Women in Puerto Rico

NCT06250738
View directory record Official record
Conditions
Psychological Distress, Cardiometabolic Syndrome
Interventions
Mindfulness-based Stress reduction program: Virtual, Home exercises
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 12, 2026, 3:12 AM EDT
Terminated Phase 4 Interventional

Liraglutide for HIV-associated Neurocognitive Disorder

NCT02743598
View directory record Official record
Conditions
HIV Infection, Diabetes Mellitus Type 2, Obesity, Overweight, Metabolic Syndrome
Interventions
Liraglutide
Drug
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2022 · Synced Oct 12, 2026, 3:12 AM EDT