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ClinicalTrials.gov public records Last synced Oct 4, 2026, 5:06 AM EDT

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Showing 73–89 of 89 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Interstitial Cystitis Bladder Pain Syndromes Clear all
Terminated Phase 2 Interventional

A Study to Evaluate the Pain Relieving Effects, Safety, and Tolerability of JNJ-42160443 for the Relief of Bladder Pain

NCT01060254
View directory record Official record
Conditions
Cystitis, Interstitial, Urologic Diseases, Urinary Bladder Diseases, Cystitis
Interventions
Placebo, JNJ-42160443
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Glendora, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Phase 1Phase 2 Interventional Results available

PK and Safety of SI-722 in IC/BPS

NCT04208087
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
SI-722, Placebo
Drug
Lead sponsor
Seikagaku Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
5
States / cities
Los Angeles, California • Murrieta, California • The Villages, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2023 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Phase 4 Interventional Results available

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis

NCT02297100
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Onabotulinumtoxin A, injections upper aspect of trigone of urinary bladder, injections on posterior bladder wall excluding the trigone
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 4, 2026, 5:06 AM EDT
Terminated Phase 3 Interventional Results available

A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain

NCT05658874
View directory record Official record
Conditions
Interstitial Cystitis, Levator Spasm, Bladder Pain Syndrome
Interventions
Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy, Pelvic floor physical therapy, Usual Urogynecologic care, Bladder Instillation, Vaginal estrogen, Methenamine, Amitriptyline/Gabapentin
Drug · Procedure · Behavioral + 1 more
Lead sponsor
Jocelyn Fitzgerald
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 4, 2026, 5:06 AM EDT
Completed No phase listed Observational

Urinary Biomarkers Characteristic to Interstitial Cystitis

NCT00971568
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Phase 2 Interventional

Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome

NCT01393223
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
LP-08 80mg, Normal saline, LP-08 20mg
Drug
Lead sponsor
Lipella Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Interstitial Cystitis: Examination of the Central Autonomic Network

NCT03008382
View directory record Official record
Conditions
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interventions
Metoprolol Tartrate Oral Tablet, Placebo Oral Tablet, No intervention- observational sub-study
Drug · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Evanston, Illinois • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 4, 2026, 5:06 AM EDT
Terminated Phase 2 Interventional

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

NCT05740007
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
IW-3300 rectal foam, Placebo
Drug
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
53
States / cities
Mobile, Alabama • Scottsdale, Arizona • Tucson, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 4, 2026, 5:06 AM EDT
Active, not recruiting Phase 2 Interventional

Bladder Directed vs. Pelvic Floor Therapy in IC/BPS

NCT02870738
View directory record Official record
Conditions
Cystitis, Interstitial, Painful Bladder Syndrome
Interventions
Pelvic Floor Physical Therapy, Bladder Instillations
Procedure · Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS

NCT02550561
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome
Interventions
Posterior Tibial Nerve Stimulation
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 4, 2026, 5:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlating Ic/Pbs Symptoms With Urine Biomarkers

NCT00817388
View directory record Official record
Conditions
Interstitial Cystitis, Pelvic Pain
Interventions
No intervention
Other
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 7, 2010 · Synced Oct 4, 2026, 5:06 AM EDT
Terminated Phase 2 Interventional Results available

The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)

NCT01569438
View directory record Official record
Conditions
Bladder Pain Syndrome
Interventions
Gefapixant, Placebo
Drug
Lead sponsor
Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
41
States / cities
Glendale, Alabama • Homewood, Alabama • Mobile, Alabama + 37 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Not applicable Interventional

Physical Therapy in Women With Interstitial Cystitis

NCT00733603
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome
Interventions
Global Therapeutic Massages (GTM), Myofascial Tissue Manipulation (MTM)
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
10
States / cities
San Diego, California • Stanford, California • Maywood, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Not applicable Interventional

Learning to THRIVE (L2T) Program Pilot

NCT07797010
View directory record Official record
Conditions
Interstitial Cystitis and Bladder Pain Syndrome
Interventions
Learning to THRIVE (L2T) Program
Behavioral
Lead sponsor
University of Indianapolis
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 4, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional

New Approaches to Nerve Stimulation Therapy for Bladder Pain Syndrome

NCT06204874
View directory record Official record
Conditions
Bladder Pain Syndrome
Interventions
Pulsed radiofrequency ablation
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 4, 2026, 5:06 AM EDT
Completed Not applicable Interventional

What is the Optimal Technique for Hydrodistention?

NCT05456308
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Hydrodistention during cystoscope
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 4, 2026, 5:06 AM EDT
Terminated Phase 2 Interventional Results available

Engage 24: Evaluation of the Safety and Effectiveness of URG101 in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

NCT02591199
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
URG101, Placebo, Lidocaine, Heparin
Drug
Lead sponsor
Urigen
Industry
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
11
States / cities
Escondido, California • San Diego, California • Cartersville, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 4, 2026, 5:06 AM EDT