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ClinicalTrials.gov public records Last synced May 21, 2026, 11:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–41 of 17 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Intestinal Perforation Clear all
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Peptic Ulcer
Interventions
Endoscopic Translumenal Omental Patch
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced May 21, 2026, 11:00 PM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
PVI, Usual Care
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced May 21, 2026, 11:00 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Appendicitis, Appendicitis; Perforation
Interventions
Lactobacillus rhamnosus GG (LGG) Probiotic, Placebo
Dietary Supplement
Lead sponsor
Children's Health
Other
Eligibility
4 Years to 18 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced May 21, 2026, 11:00 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Intestinal Perforation, Intestinal Obstruction, Trauma Abdomen
Interventions
there is no intervention involved in this study
Other
Lead sponsor
New York Medical College
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced May 21, 2026, 11:00 PM EDT
Terminated Phase 3 Interventional Results available
View directory record Official record
Conditions
Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain, Appendicitis, Rupture, Infection, Intestinal Perforation, Peritonitis, Ileus
Interventions
Doripenem, Meropenem placebo, Meropenem, Doripenem placebo, Amoxicillin/clavulanate potassium
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
3 Months to 18 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
San Diego, California • Washington D.C., District of Columbia • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced May 21, 2026, 11:00 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Acute, Perforated Appendicitis
Interventions
Povidone-iodine irrigation, No irrigation
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced May 21, 2026, 11:00 PM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Initial appendectomy, Interval appendectomy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 17 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 18, 2016 · Synced May 21, 2026, 11:00 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Intestinal Anastomotic Leak, Intestinal Perforations
Interventions
No interventions are done
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced May 21, 2026, 11:00 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Appendicitis
Interventions
Single Incision Laparoscopic Appendectomy, 3 port laparoscopic appendectomy
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Month to 18 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced May 21, 2026, 11:00 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Perforated Appendicitis, Postoperative Infection
Interventions
Piperacillin, Tazobactam Drug Combination
Drug
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
Phoenix, Arizona • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced May 21, 2026, 11:00 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Marginal Ulcer, Chronic Ulcer Disease, Persistent Ulcer Disease, Recurrent Ulcer Disease, Late Morbidity After Gastric Bypass
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Dec 31, 2009 · Synced May 21, 2026, 11:00 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Weeks
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced May 21, 2026, 11:00 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Prematurity, Intestine Perforation, Necrotizing Enterocolitis (NEC), Short Bowel Syndrome (SBS)
Interventions
Microlipid with fish oil, Microlipid
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
1 Day to 2 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced May 21, 2026, 11:00 PM EDT
Terminated Phase 3 Interventional
View directory record Official record
Conditions
Acute Coronary Syndrome, Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
Interventions
CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin, Plavix (clopidogrel 75 mg) and aspirin
Drug
Lead sponsor
Cogentus Pharmaceuticals
Industry
Eligibility
21 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
247
States / cities
Alexander City, Alabama • Birmingham, Alabama • Geneva, Alabama + 205 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2009 · Synced May 21, 2026, 11:00 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Intestinal Perforation, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
1 Day to 16 Days
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced May 21, 2026, 11:00 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Intestinal Perforation
Interventions
Sentire
Device
Lead sponsor
Dan E. Azagury
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced May 21, 2026, 11:00 PM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
GI Bleeding, Perforation Colon, Perforation Bowel, Perforation Duodenal, Perforated Bowel, Fistula
Interventions
DAT Clip
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Orlando, Florida • Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced May 21, 2026, 11:00 PM EDT