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ClinicalTrials.gov public records Last synced Jul 24, 2026, 2:49 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Blood Loss, Surgical, Prostate Cancer, Surgery
Interventions
Hemospan (MP4OX), Ringer's lactate
Drug
Lead sponsor
Sangart
Industry
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Blood Loss, Surgical
Interventions
rThrombin, 1000 IU/mL
Biological
Lead sponsor
ZymoGenetics
Industry
Eligibility
Up to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Anesthesia
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
5 Years to 15 Years
Enrollment
1,784 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
3
States / cities
Denver, Colorado • Atlanta, Georgia • Ann Arbor, Michigan
Completed Not applicable Interventional

Cryoanalgesia Study

NCT05859061
Conditions
Pain, Postoperative
Interventions
cryoICE® system (AtriCure, Inc) with CryoSphere (CryoS) probe
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Suction Enabled Retraction Device

NCT03160170
Conditions
Surgical Blood Loss, Spinal Surgery
Interventions
SISTER device
Device
Lead sponsor
University of Miami
Other
Eligibility
22 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Conditions
Endometrial Cancer
Interventions
Sentinel node procedure, Selective staging
Procedure
Lead sponsor
Frederick R. Ueland, M.D.
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Acute Blood Loss Anemia, Postoperative Pain, Pregnancy
Interventions
non-dissection of inferior rectus sheath, control
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cervical Cancer
Interventions
Single Photon Emission Computed Tomography, Intraoperative Lymphatic Mapping
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Houston, Texas
Conditions
Blood Loss, Surgical
Interventions
PerClot Polysaccharide Hemostatic System, Arista AH
Device
Lead sponsor
Artivion Inc.
Industry
Eligibility
22 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV A Bladder Cancer, Stage IV A Rectal Cancer, Stage IV B Colon Cancer, Stage IV B Rectal Cancer
Interventions
PET Scan, CT Scan, fludeoxyglucose F 18, computer-aided detection/diagnosis
Procedure · Radiation
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Breast Cancer, Perioperative/Postoperative Complications
Interventions
fibrin sealant (Beriplast P, TISSEEL VH), breast reconstruction
Drug · Procedure
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Peri-operative Pain and Root Canal Therapy

NCT01201681
Conditions
Post-operative Tooth Pain, Root Canal Therapy
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
19 Years to 70 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
7
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Conditions
Blood Loss, Surgical
Interventions
Ecallantide, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Aurora, Colorado + 8 more
Terminated Not applicable Interventional Results available

Infrared Pupillometry During General Anesthesia to Predict Pain

NCT02058511
Conditions
Postoperative Pain, Objective Assessment of Sedation
Interventions
Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs
Drug · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Francisco, California
Conditions
Pain, Postoperative
Interventions
Pre-op percutaneous rectus sheath block, Intra-operative rectus sheath block, Ropivacaine
Procedure · Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
3 Years to 18 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Conditions
Ovarian Cancer
Interventions
OTL38, intraoperative imaging camera system
Drug · Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Incidence Between Two Techniques

NCT01832025
Conditions
Edentulous Posterior Maxilla
Interventions
internal maxillary sinus floor elevation technique, external maxillary sinus floor elevation technique
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying

NCT07140289
Conditions
Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists, Intermittent Fasting, Intraoperative Complication Due to Anesthesia, Respiratory Aspiration of Gastric Contents
Interventions
Ultrasound of gastric contents
Diagnostic Test
Lead sponsor
Wael Saasouh, MD
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Blood Loss, Surgical
Interventions
rThrombin, 1000 IU/mL
Biological
Lead sponsor
ZymoGenetics
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tuscon, Arizona
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

NCT02989597
Conditions
Pain, Postoperative
Interventions
Methadone Hydrochloride, Standard pain regimen, Spinal Fusion Surgery, Dexamethasone, Ketamine, Remifentanil, Sufentanil
Drug · Other · Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Completed Phase 4 Interventional Accepts healthy volunteers

Oral and Intravenous Tranexamic Acid in Lumbar Spine Surgery

NCT03037515
Conditions
Blood Loss, Surgical, Blood Loss Anemia
Interventions
Tranexamic Acid
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Pain, Postoperative, Chronic Pain
Interventions
Methadone, Fentanyl
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Post Operative Pain
Interventions
Anterior Cruciate ligament reconstruction bone patellar tendon bone autograft, Platelet Rich Plasma
Procedure · Biological
Lead sponsor
Brian Walters
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Intraoperative Bleeding
Interventions
BioFoam Surgical Matrix, Gelfoam Plus
Device
Lead sponsor
CryoLife, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Palo Alto, California • Seattle, Washington