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ClinicalTrials.gov public records Last synced Nov 7, 2026, 10:28 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 113 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Isolation, Social Clear all

Conditions: Chronic Pain
Interventions: Group Acupuncture, Integrative Group Medical Visits; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Social Isolation, Emotional Disorder
Interventions: Coping Crew; Behavioral
Lead sponsor: Ohio University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Malnutrition, Isolation, Depression, Anxiety, Sedentary Behavior, Loneliness
Interventions: Telephone-based coaching; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 75 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Baltimore, Maryland • Boston, Massachusetts

Conditions: Loneliness, Social Isolation
Interventions: Need to Be Needed Intervention, Active Control Group; Behavioral · Other
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2035
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Aging Well
Interventions: Yoga Via Telehealth - Immediately, Yoga Via Telehealth - Waitlisted; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 60 Years and older
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Social Activity
Interventions: oxytocin (Pitocin); Drug
Lead sponsor: Claremont Graduate University; Other
Eligibility: 50 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Mental Health
Interventions: Telephone Reminiscence Program; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 60 Years and older
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Chronic Pain
Interventions: group acupuncture, Integrative Group Medical Visits; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Loneliness, Social Isolation, Rural Health
Interventions: Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Social Isolation, Loneliness, Caregiver Burnout
Interventions: Engage coaching; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 40 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Aging, Physical Dependence
Interventions: VIPA and companion booklet; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 65 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Adolescent, Young Adult, Cancer, Physical Activity, Psychological Distress, Social Isolation
Interventions: Physical Activity Intervention; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 15 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Social Isolation, Loneliness
Interventions: Connect for Caregivers; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 40 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Hiv, Depression in Old Age, Isolation, Social, Aging
Interventions: Virtual Village; Other
Lead sponsor: University of California, Riverside; Other
Eligibility: 50 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Riverside, California

Conditions: Chronic Pain
Interventions: CBT for Loneliness, CBT for Chronic Pain; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Canandaigua, New York

Conditions: Cognitive Decline, Social Isolation, Health Behaviors, Self Efficacy
Interventions: Wits Workout Program, Control Group that receives intervention after the study; Behavioral · Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 50 Years and older
Enrollment: 285 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Social Isolation, Aging, Physical Activity
Interventions: Intervention Condition, Control Condition; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 60 Years and older
Enrollment: 181 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 2
States / cities: Miami, Florida • New York, New York

Conditions: Loneliness, Social Isolation, Depression
Interventions: Phone Call; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Senior Abuse
Interventions: Treatment; Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 65 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression
Interventions: Empower@Home; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 60 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders, Mental Disorder
Interventions: Empower@Home; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 60 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Schizotypy
Interventions: Social Judgment Paradigm; Behavioral
Lead sponsor: Central Connecticut State University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: New Britain, Connecticut

Conditions: Loneliness, Depression, Anxiety, Alcohol Abuse, Drug Abuse
Interventions: Not listed
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 35 Years
Enrollment: 1,008 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Aging, Mild Cognitive Impairment, Aging Well
Interventions: OneClick Social Engagement Intervention, OneClick Social Engagement Intervention Extension; Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 65 Years and older
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Champaign, Illinois • Chicago, Illinois

Search by objective public record fields.

Group-based Integrative Pain Management in Primary Care Safety Net Clinics

Acceptability/Feasibility of COVID-19 Intervention

Feasibility of Remote Home Support Coaches (SOCIAL Study)

Need to be Needed (N2BN) Intervention

In-home Yoga for Seniors

Oxytocin and Social Behavior Over the Lifespan

Effect of a Telephone Reminiscence Intervention on Mental Health

Group-based Integrative Pain Management (IPMP+ Pilot)

Fostering Agricultural Relationships and Meaning - Thriving on Kinship

Engage Coaching for Latinos

Intelligent Personal Assistant for Managing Depression in Homebound Older Adults

Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With Cancer

Connection for Latinos Caring for a Loved One With Dementia

Creating a Virtual Village for People Aging With HIV During COVID-19

Pain and Loneliness

Evaluation of the Wits Workout Wellness Program for Older Adults

A Personalized Health Behavior System

Telephone Calls for Health for Homebound Older Adults

The Impact of Social Phone Calls With Isolated Older Adults Receiving Protective Services for Abuse, Neglect and/or Exploitation

Empower@Home: A Feasibility Pilot

The Preliminary Effects of Empower@Home

Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study

Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology

Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology