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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:03 AM EDT

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Showing 49–72 of 254 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Kidney Calculi Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Renal Metabolism of Glycolate to Oxalate

NCT04437225
View directory record Official record
Conditions
Healthy
Interventions
Low oxalate controlled Diet, Primed, continuous intravenous infusion of 13C2-Glycolate, Bolus intravenous infusion of 13C2-Glycolate, Oral bolus administration of 13C2-Glycolate
Dietary Supplement · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional

FANS vs CVAC for Medium to Large Stones

NCT07514351
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
ureteroscopy, CVAC
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Terminated Not applicable Interventional Results available

MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy

NCT03995758
View directory record Official record
Conditions
Kidney Calculi
Interventions
MOSES
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 21, 2026, 4:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy

NCT06149455
View directory record Official record
Conditions
Infections, Urinary Tract, Nephrolithiasis
Interventions
Duration of antibiotics
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 4 Interventional

Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment

NCT03229889
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Cialis 5Mg Tablet, Flomax 0.4Mg Capsule, Cialis + Flomax, Placebo
Drug · Combination Product
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 99 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Recruiting No phase listed Observational

Prospective Research Rare Kidney Stones (ProRKS)

NCT02780297
View directory record Official record
Conditions
Hyperoxaluria, Cystinuria, Dent Disease, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
8
States / cities
Birmingham, Alabama • Jacksonville, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate and Citrate

NCT05334979
View directory record Official record
Conditions
Kidney Stone, Normal Controls
Interventions
Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Not listed No phase listed Observational

Keller Prehospital Ultrasound Study

NCT01074112
View directory record Official record
Conditions
Ultrasonography, Multiple Trauma, Kidney Calculi, Aortic Aneurysm, Abdominal, Pregnancy, Catheterization, Venous
Interventions
EFAST exam, Pelvic Ultrasound, Ultrasound Guided Vascular Access, Focused Ultrasound Scan, Cardiac Ultrasound
Device · Procedure
Lead sponsor
Keller Fire Rescue
Government
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Keller, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2010 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 3 Interventional Results available

Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.

NCT03584373
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Ketorolac Oral Tablet [Toradol], Acetaminophen, Oxycodone Acetaminophen
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

NCT00587041
View directory record Official record
Conditions
Nephrolithiasis, Hyperoxaluria, Crohn's Disease
Interventions
Oxadrop, Agri-King Synbiotic (AKSB), Placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones

NCT03526458
View directory record Official record
Conditions
Stone Ureter, Stone;Renal, Surgery
Interventions
Holmium:YAG laser
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional

Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis

NCT06269783
View directory record Official record
Conditions
Kidney Stone, Urolithiasis, Nephrolithiasis
Interventions
sipIT
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional

Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney

NCT02210650
View directory record Official record
Conditions
Ureteral Stones, Kidney Stones
Interventions
Symptomatic stone removal, Asymptomatic kidney stones and ureteral stone removed
Procedure
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
4
States / cities
Indianapolis, Indiana • Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 21, 2026, 4:03 AM EDT
Not listed Phase 4 Interventional

Daily Versus Twice Per Day Tamsulosin for Ureteral Stent Symptoms

NCT03799120
View directory record Official record
Conditions
Ureteral Diseases
Interventions
Tamsulosin BID, Placebo
Drug · Other
Lead sponsor
Gundersen Lutheran Medical Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional

The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients

NCT00600405
View directory record Official record
Conditions
Nephrolithiasis, Ureteral Calculi
Interventions
tamsulosin, Standard therapy with ibuprofen and oxycodone.
Drug
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jan 25, 2008 · Synced Oct 21, 2026, 4:03 AM EDT
Recruiting Phase 2 Interventional

Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)

NCT07587021
View directory record Official record
Conditions
Primary Hyperoxaluria Type 1, PH1
Interventions
YOLT-203, Placebo
Genetic · Drug
Lead sponsor
YolTech Therapeutics Co., Ltd
Industry
Eligibility
6 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Birmingham, Alabama • Aurora, Colorado • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Completed No phase listed Observational

Percutaneous Nephrolithotomy: A Registry and Database

NCT00159393
View directory record Official record
Conditions
Nephrolithiasis
Interventions
registry and database
Other
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
1,697 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2018
U.S. locations
2
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 21, 2026, 4:03 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Kidney Stone Inflammation

NCT06436235
View directory record Official record
Conditions
Kidney Stone, Stone, Kidney
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 21, 2026, 4:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi

NCT05869890
View directory record Official record
Conditions
Renal Calculi
Interventions
MOSES laser system
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones

NCT04597619
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Novel Nonopioid Pathway
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 1 Interventional

Pharmacokinetic and Safety Study of OMS201 in Subjects Undergoing Ureteroscopic Treatment for Removal of Urinary Tract-Located Stones

NCT00599664
View directory record Official record
Conditions
Urinary Calculi, Urinary Stones, Urinary Tract Stones
Interventions
OMS201, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
Orange, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2010 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 4 Interventional Results available

Narcotic-Free Percutaneous Nephrolithotomy

NCT05924165
View directory record Official record
Conditions
Nephrolithiasis
Interventions
5mg Oxycodone, Q6 PRN, 10mg Ketorolac, Q6 PRN
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Phase 2 Interventional

A Phase 2a Study of LLX-424 in Patients With a History of Kidney Stones

NCT06932146
View directory record Official record
Conditions
Kidney Stones
Interventions
LLX-424
Drug
Lead sponsor
Lilac Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Saint Paul, Minnesota • Springfield, Missouri • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 21, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Trial Assessing Renal Damage During Ureteroscopy

NCT05350423
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Oct 21, 2026, 4:03 AM EDT