- Conditions
- Total Knee Anthroplasty
- Interventions
- Total Knee Arthroplasty Medial Parapatellar Approach, Total Knee Arthroplasty Subvastus Approach
- Procedure
- Lead sponsor
- Total Joint Specialists
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Sandy Springs, Georgia
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Showing 1–24
of 80
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Infection of Total Knee Joint Prosthesis
- Interventions
- Bactisure
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Lexington, Kentucky • Louisville, Kentucky + 2 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Zimmer, Stryker
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Transfemoral Amputation
- Interventions
- MIT Powered Leg
- Device
- Lead sponsor
- Massachusetts Institute of Technology
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
- Interventions
- BioPoly, surgical standard of care (SSOC)
- Device · Procedure
- Lead sponsor
- BioPoly LLC
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Fort Wayne, Indiana • Indianapolis, Indiana • Rochester, Minnesota + 1 more
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- NexGen CR-Flex Fixed Bearing Knee, NexGen CR Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 189 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2010
- U.S. locations
- 8
- States / cities
- Milford, Delaware • Chicago, Illinois • Rockford, Illinois + 5 more
- Conditions
- Arthrofibrosis of Knee
- Interventions
- Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty
- Radiation · Procedure
- Lead sponsor
- Mount Sinai Hospital, Canada
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Salt Lake City, Utah
- Conditions
- Osteoarthritis, Knee
- Interventions
- Off-the-Shelf Implant Total Knee Replacement, Customized Implant Total Knee Replacement
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 59 participants
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Kettering, Ohio
- Conditions
- Knee Prosthesis, Knee Arthroplasty
- Interventions
- DePuy fixed-bearing Total Condylar III (TC3) TKA, DePuy PFC Rotating Platform TC3 TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Knoxville, Tennessee
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
- Interventions
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Total Knee Replacement Surgery
- Interventions
- ultrasound guidance alone, ultrasound guidance and needle stimulation, ultrasound guidance and catheter stimulation
- Procedure
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 453 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Osteoarthritis of the Knee
- Interventions
- ATTUNE Cementless CR Fixed Bearing, ATTUNE Cementless PS Fixed Bearing
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 15
- States / cities
- Irvine, California • Bradenton, Florida • DeLand, Florida + 10 more
- Conditions
- Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Implant, Knee Injuries
- Interventions
- Klassic Knee System
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Shoulder Injuries, Knee Injuries, Hip Injuries
- Interventions
- Standard of Care Treatment
- Device
- Lead sponsor
- Stryker Endoscopy
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Englewood, Colorado • San Antonio, Texas
- Conditions
- Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
- Interventions
- Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
- Biological · Other
- Lead sponsor
- ISTO Technologies, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
- Conditions
- Knee Prosthesis
- Interventions
- Stryker posterior cruciat retaining (PCR) total knee arthroplasty (TKA), Zimmer PCR TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 4
- States / cities
- Knoxville, Tennessee
- Conditions
- Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
- Interventions
- NUsurface® Meniscus Implant
- Device
- Lead sponsor
- Phoenix Kinetics
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 115 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2024
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • La Mesa, California • Long Beach, California + 10 more
- Conditions
- Complications; Arthroplasty
- Interventions
- Conformis CR Total Knee Replacement, Off the Shelf
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 2
- States / cities
- Knoxville, Tennessee
- Conditions
- Total Knee Arthroplasty
- Interventions
- Hydrocortisone, Placebo
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cartilage Defect
- Interventions
- REcycled CartiLage Auto/Allo IMplantation
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Osteoarthritis, Knee
- Interventions
- Performance Clinical Outcome Test
- Other
- Lead sponsor
- Canary Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 6
- States / cities
- Frisco, Colorado • South Bend, Indiana • Jackson, Mississippi + 3 more
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Knee Disease, Knee Infection
- Interventions
- [F-18]MHF
- Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Osteoarthritis, Knee
- Interventions
- BION
- Device
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- Los Angeles, California