Cartilage Autograft Implantation System (CAIS) for the Repair of Knee Cartilage Through Cartilage Regeneration
Public ClinicalTrials.gov record NCT00881023. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Pivotal Study to Evaluate the Safety and Efficacy of the Cartilage Autograft Implantation System (CAIS) for the Surgical Treatment of Articular Cartilage Lesions of the Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Cartilage Autograft Implantation System (CAIS) is designed as a single surgical treatment of damaged knee cartilage using the subject's own healthy cartilage obtained from a non-weight or low weight-bearing region. CAIS is indicated for the repair of articular cartilage lesions and osteochondritis dissecans (OCD) of the knee through cartilage regeneration.
Study identification
- NCT ID
- NCT00881023
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 75 participants
Conditions and interventions
Interventions
- Microfracture Procedure
- Cartilage Autograft Implantation System Device
Procedure · Device
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2010 (Type not available)
- Primary completion
- Dec 2014 (Actual)
- Completion
- Dec 2014 (Actual)
- Last update posted
- Aug 3, 2016
2010 – 2014
United States locations
- U.S. sites
- 27
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tucson Orthopaedic Institute | Tucson | Arizona | 85712 | — |
| MWMC Bentonville Hospital | Bentonville | Arkansas | 72712 | — |
| CORE Orthopaedic Medical Center | Encinitas | California | 92024 | — |
| Santa Monica Orthopaedic Group | Santa Monica | California | 90404 | — |
| Southern California Orthopaedic Group | Van Nuys | California | 91405 | — |
| JDP Medical Research, LLC | Denver | Colorado | 80014 | — |
| Shrock Orthopedic Research | Fort Lauderdale | Florida | 33316 | — |
| Andrews Institute | Gulf Breeze | Florida | 32561 | — |
| Florida Orthopaedics Institute and Research Foundation | Tampa | Florida | 33637 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| OrthoIndy | Indianapolis | Indiana | 46237 | — |
| University of Kentucky Medical Center | Lexington | Kentucky | 40536-0284 | — |
| Harvard Vanguard / New England Baptist Hospital | Chestnut Hill | Massachusetts | 02467 | — |
| UMass Medical Center - Orthopedic Research | Worcester | Massachusetts | 01655 | — |
| TRIA Orthopaedic Center | Bloomington | Minnesota | 55431 | — |
| University of Missouri | Columbia | Missouri | 65211 | — |
| Rothman Institute | Egg Harbor | New Jersey | 08234 | — |
| University Orthopaedic Group LLC | New Brunswick | New Jersey | 08901 | — |
| New York University School of Medicine | New York | New York | 10003 | — |
| University of Rochester Medical Center | Rochester | New York | 14618 | — |
| Orlin & Cohen Orthopedic Group | Rockville Centre | New York | 11570 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Orthopaedic Research Foundation of the Carolinas | Greenville | South Carolina | 29615 | — |
| OrthoMemphis, PC | Memphis | Tennessee | 38120 | — |
| Basin Orthopedic Surgical Specialists | Odessa | Texas | 79761 | — |
| Richmond Bone & Joint Clinic, P.A. | Sugar Land | Texas | 77478 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00881023, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2016 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00881023 live on ClinicalTrials.gov.