- Conditions
- Knee Pain Chronic
- Interventions
- Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 178 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
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Showing 1–24
of 161
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee, Lower Limb Amputation Above Knee, Knee Arthropathy, Shoulder Arthroplasty, Rotator Cuff Repair, Video-Assisted Thoracoscopic Surgery (VATS), Skin Grafting
- Interventions
- Cryoneurolysis (active), Sham cryoneurolysis procedure
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Osteoarthritis
- Interventions
- CNTX-4975, Placebo
- Drug · Other
- Lead sponsor
- Centrexion Therapeutics
- Industry
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 18 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 852 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis, Chronic Pain, Kinesiophobia
- Interventions
- Virtual Reality Nature scene plus heart rate variability biofeedback phone application
- Behavioral
- Lead sponsor
- Arizona State University
- Other
- Eligibility
- 45 Years to 74 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Arthritis, Degenerative
- Interventions
- Experimental: 3VM1001 active 2g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 4 times daily, Placebo: 3VM1001 vehicle 2g Cream 3 times daily, Placebo: 3VM1001 vehicle 3g Cream 3 times daily, Placebo: 3VM1001 vehicle 3g Cream 4 times daily
- Drug
- Lead sponsor
- CDA Research Group, Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Pain, Chronic
- Interventions
- Experimental: Group #1: Virtual Reality Headset, Group 2 No Virtual Reality Headset
- Other
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Pain, Compliance, Patient, Chronic Low Back Pain, Knee Pain Chronic
- Interventions
- Number of Exercises, Type of Instruction, Delivery Type, Mobile Reminder
- Other
- Lead sponsor
- Dan Rhon
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Osteoarthritis (OA) of the Knee
- Interventions
- Neural Ice, Triamcinolone acetate
- Device · Drug
- Lead sponsor
- Brixton Biosciences, Inc.
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 263 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 15
- States / cities
- Larkspur, California • Washington D.C., District of Columbia • Gainesville, Florida + 12 more
- Conditions
- Knee Osteoarthritis, Degenerative Joint Disease of Knee
- Interventions
- Embozene MicroSpheres
- Device
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 40 Years to 79 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Santa Monica, California
- Conditions
- Chronic Knee Pain, Osteoarthritis, Knee
- Interventions
- Nerve Block with Radiofrequency Ablation, Nerve Block with Sham Radiofrequency Ablation
- Procedure
- Lead sponsor
- Randall Brewer, MD, CPI
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Shreveport, Louisiana
- Conditions
- Osteoarthritis, Knee
- Interventions
- Placebo, CNTX-4975-05
- Drug
- Lead sponsor
- Centrexion Therapeutics
- Industry
- Eligibility
- 40 Years to 95 Years
- Enrollment
- 332 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 30
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Carmichael, California + 23 more
- Conditions
- Joint Disease, Pain, Acute, Pain, Chronic
- Interventions
- Cymbalta, Placebo
- Drug · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee
- Interventions
- StimRouter Neuromodulation System
- Device
- Lead sponsor
- Bioventus LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 13 participants
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Livonia, Michigan
- Conditions
- Chronic Pain, Opioid Use, Adductor Canal Block, Total Knee Arthroplasty
- Interventions
- ambIT pump with catheter, ambIT pump with sham catheter
- Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Burns, Knee Injuries, Opioid Use, Pain
- Interventions
- Opioid Use 90-Days Post Treatment
- Behavioral
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 0 Years to 18 Years
- Enrollment
- 980 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
- Interventions
- Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
- Other
- Lead sponsor
- Creighton University
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Joint (Knee or Hip Replacement)
- Interventions
- Sleep banking
- Behavioral
- Lead sponsor
- Defense and Veterans Center for Integrative Pain Management
- Other
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Knee Osteoarthritis (OA), Chronic Pain, Chronic Knee Pain
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Bone Marrow Edema, Knee Osteoarthritis, Knee Pain Chronic
- Interventions
- Focused extracorporeal shockwave therapy
- Device
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Cedar Knolls, New Jersey • West Orange, New Jersey
- Conditions
- Knee Osteoarthritis
- Interventions
- Diet
- Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Degenerative Arthritis
- Interventions
- Placebo, Ibuprofen modified release tablet 800 mg
- Drug
- Lead sponsor
- Overseas Pharmaceuticals, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 7
- States / cities
- Cerritos, California • Garden Grove, California • Santa Ana, California + 4 more
- Conditions
- Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Pain, Arthralgia, Joint Pain
- Interventions
- JNJ-42160443, Placebo
- Drug
- Lead sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 467 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 52
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 49 more
- Conditions
- Knee Osteoarthritis, Chronic Pain
- Interventions
- Technology-implemented exercise therapy, Traditional Physical Therapy
- Other
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York