- Conditions
- Knee Arthritis, Osteoarthritis
- Interventions
- Knee sleeve
- Device
- Lead sponsor
- Margaret L Gourlay, MD, MPH
- Other
- Eligibility
- 50 Years to 64 Years
- Enrollment
- 235 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- Springfield, Massachusetts
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Showing 1–24
of 161
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
- Interventions
- Zimmer Biomet Persona Ti-Nidium Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2034
- U.S. locations
- 7
- States / cities
- Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic
- Interventions
- Shoulder/Hip/Knee Embolization with Embozene Microspheres
- Device
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 25 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- TLC599, DSP, Normal Saline
- Drug · Other
- Lead sponsor
- Taiwan Liposome Company
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 504 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 41
- States / cities
- Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 33 more
- Conditions
- Osteoarthritis, Chronic Pain
- Interventions
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release), Placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 547 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 81
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 69 more
- Conditions
- Chronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
- Interventions
- Cognitive Training + fMRI
- Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Osteoarthritis of Knee, Knee Pain Chronic
- Interventions
- CAPPA, Health education
- Behavioral
- Lead sponsor
- Marquette University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Knee Osteoarthritis, Chronic Pain, Kinesiophobia
- Interventions
- Virtual Reality Nature scene plus heart rate variability biofeedback phone application
- Behavioral
- Lead sponsor
- Arizona State University
- Other
- Eligibility
- 45 Years to 74 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Pain, Chronic
- Interventions
- Experimental: Group #1: Virtual Reality Headset, Group 2 No Virtual Reality Headset
- Other
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Musculoskeletal Pain, Chronic Shoulder Pain, Chronic Knee Pain
- Interventions
- Laterality Training, Sham (No Treatment)
- Behavioral · Other
- Lead sponsor
- Hawaii Pacific University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Moline, Illinois • Davenport, Iowa
- Conditions
- Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
- Interventions
- Cebranopadol (GRT6005) Low-Dose Range, Cebranopadol (GRT6005) High-Dose Range, Placebo, Oxycodone CR
- Drug
- Lead sponsor
- Tris Pharma, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 619 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 83
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 74 more
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Interventions
- mymobility with Apple Watch
- Other
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6,559 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 26
- States / cities
- Fremont, California • Irvine, California • Redwood City, California + 23 more
- Conditions
- Osteo Arthritis Knee, Knee Pain Chronic, Surgery
- Interventions
- Savoring Meditation, Pain Self-Management and Education
- Behavioral
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Joint Disease, Arthritis, Osteo Arthritis Knee, Musculoskeletal Disease
- Interventions
- HAM and HUMCWJ Injections
- Procedure
- Lead sponsor
- Sport and Spine Rehab Clinical Research Foundation
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis
- Interventions
- Acupuncture
- Procedure
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- NIH
- Eligibility
- 40 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2007
- U.S. locations
- 3
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Interventions
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Behavioral
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Knee Osteoarthritis
- Interventions
- Diet
- Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Knee Pain Chronic
- Interventions
- transcranial direct current stimulation, physical therapy
- Device · Other
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Knee
- Interventions
- Placebo, CNTX-4975-05
- Drug
- Lead sponsor
- Centrexion Therapeutics
- Industry
- Eligibility
- 40 Years to 95 Years
- Enrollment
- 332 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 30
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Carmichael, California + 23 more
- Conditions
- Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis, Arthritis, Degenerative
- Interventions
- Cooled radiofrequency ablation
- Device
- Lead sponsor
- International Spine, Pain and Performance Center
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Arlington, Virginia
- Conditions
- Osteoarthritis, Knee
- Interventions
- acupuncture
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Alzheimer&Amp;#39;s Disease, Other Dementias
- Interventions
- Active tDCS paired with active online chair yoga
- Device
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Knee Pain Chronic, Knee Swelling Pain, Arterial Occlusion
- Interventions
- Embozene Microspheres
- Device
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 40 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee, Lower Limb Amputation Above Knee, Knee Arthropathy, Shoulder Arthroplasty, Rotator Cuff Repair, Video-Assisted Thoracoscopic Surgery (VATS), Skin Grafting
- Interventions
- Cryoneurolysis (active), Sham cryoneurolysis procedure
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California