- Conditions
- Arthrofibrosis of Knee
- Interventions
- Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty
- Radiation · Procedure
- Lead sponsor
- Mount Sinai Hospital, Canada
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Salt Lake City, Utah
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Showing 25–48
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- Conditions
- Prosthesis-Related Infections
- Interventions
- Oral Antibiotics
- Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 185 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • Winfield, Illinois • Philadelphia, Pennsylvania + 1 more
- Conditions
- Prosthesis User, Amputation
- Interventions
- NAVii
- Device
- Lead sponsor
- Össur Iceland ehf
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 3
- States / cities
- Merrillville, Indiana • Bay City, Michigan • Perrysburg, Ohio
- Conditions
- Osteoarthritis
- Interventions
- Off the Shelf Total Knee Replacement, ConforMIS iTotal Knee Replacement
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 215 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 8
- States / cities
- La Jolla, California • San Diego, California • Parker, Colorado + 5 more
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Interventions
- Stereotactic guidance system
- Device
- Lead sponsor
- Ormonde M. Mahoney, MD
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
- Interventions
- Rivaroxaban
- Drug
- Lead sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 5
- States / cities
- Denver, Colorado • Hollywood, Florida • Tamarac, Florida + 2 more
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 4
- States / cities
- La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more
- Conditions
- Degenerative Arthritis, Osteoarthritis, Rheumatoid Arthritis, Knee Arthritis
- Interventions
- Duracon®, Vanguard™
- Device
- Lead sponsor
- Biomet Orthopedics, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Warsaw, Indiana
- Conditions
- Infection of Total Knee Joint Prosthesis
- Interventions
- Bactisure
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Lexington, Kentucky • Louisville, Kentucky + 2 more
- Conditions
- Transfemoral Amputation
- Interventions
- MIT Powered Knee
- Device
- Lead sponsor
- Massachusetts Institute of Technology
- Other
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2026
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Unilateral Traumatic Amputation, Amputation, Traumatic
- Interventions
- Powered ankle prosthesis, Dynamic Response Foot
- Device
- Lead sponsor
- Deanna H Gates
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Amputation, Prosthesis User
- Interventions
- Xtremity Polymer Prosthetic Socket
- Device
- Lead sponsor
- Medical Creations, Inc.
- Industry
- Eligibility
- 19 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Revision Arthroplasty, Knee
- Interventions
- Condylar Constrained knee system. ( NexGen Legacy Condylar Constrained Knee by Zimmer Biomet), Rotating Hinge Knee ( NexGen Rotating Hinge Knee by Zimmer Biomet)
- Device
- Lead sponsor
- Medstar Health Research Institute
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 186 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2037
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Olney, Maryland
- Conditions
- Amputation of Knee, Back Pain, Osteo Arthritis Knee
- Interventions
- Haptic Biofeedback from SageMotion Biofeedback System
- Device
- Lead sponsor
- San Jose State University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 2
- States / cities
- Palo Alto, California • San Francisco, California
- Conditions
- Transfemoral Amputees
- Interventions
- Medial thighplasty with or without thigh liposuction
- Procedure
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Knee Prosthesis
- Interventions
- Stryker posterior cruciat retaining (PCR) total knee arthroplasty (TKA), Zimmer PCR TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 4
- States / cities
- Knoxville, Tennessee
- Conditions
- Traumatic Amputation of Lower Extremity
- Interventions
- Powered ankle-foot prosthesis, No device
- Device · Other
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Transfemoral Amputation, Limb Loss, Limb Absence
- Interventions
- Powered prosthetic knee joint, Conventional prosthetic knee joint
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis
- Interventions
- iUni® Unicompartmental Knee Resurfacing Device
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2023
- U.S. locations
- 8
- States / cities
- Little Rock, Arkansas • La Quinta, California • Monterey, California + 5 more
- Conditions
- Osteoarthritis
- Interventions
- Latella Knee Implant System
- Device
- Lead sponsor
- Cotera, Inc.
- Industry
- Eligibility
- 30 Years to 70 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Chicago, Illinois
- Conditions
- Osteoarthritis
- Interventions
- Total and Unicompartment Knee Replacement
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Leesburg, Florida
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- NexGen CR-Flex Fixed Bearing Knee, NexGen CR Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 189 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2010
- U.S. locations
- 8
- States / cities
- Milford, Delaware • Chicago, Illinois • Rockford, Illinois + 5 more
- Conditions
- Total Knee Arthroplasty
- Interventions
- Hydrocortisone, Placebo
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Prosthesis User, Amputation
- Interventions
- Power Knee
- Device
- Lead sponsor
- Össur Iceland ehf
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Silver Spring, Maryland • Boston, Massachusetts