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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Knee Repair Clear all
Terminated Not applicable Interventional

Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation

NCT02185001
View directory record Official record
Conditions
Dislocated Patella, Torn Medial Patellofemoral Ligament
Interventions
Direct Medial Patellofemoral Ligament (MPFL) Repair, Physical therapy
Procedure
Lead sponsor
Orthopedic Specialty Institute
Industry
Eligibility
10 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Coeur d'Alene, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Phase 4 Interventional

Efficacy of the SurgiStim3 Electrical Stimulation Device in Persons Undergoing Anterior Cruciate Ligament Repair

NCT00717171
View directory record Official record
Conditions
Anterior Cruciate Ligament
Interventions
SurgiStim3
Device
Lead sponsor
VQ OrthoCare
Industry
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Van Nuys, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2009 · Synced Jul 22, 2026, 10:40 AM EDT
Recruiting Not applicable Interventional

A Nanoscopic Second Look Into the Knee Joint

NCT07709819
View directory record Official record
Conditions
Meniscal Tears
Interventions
Nanoscopic Arthroscopy of the Knee
Procedure
Lead sponsor
Angelina Vera MD
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Completed No phase listed Observational Results available

Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal Transplantations

NCT04903106
View directory record Official record
Conditions
Meniscus Tear
Interventions
FAST-FIX FLEX Meniscal Repair System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
16 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Phase 4 Interventional Results available

iPACK for Post-op Pain Following ACL Reconstruction

NCT05498870
View directory record Official record
Conditions
ACL Injury, Post Operative Pain
Interventions
Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated No phase listed Observational

Study of the ConforMIS iDuo(R) G2

NCT01564641
View directory record Official record
Conditions
Bicompartmental Osteoarthritis
Interventions
iDuo G2
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
3
States / cities
New Castle, Indiana • New Orleans, Louisiana • Morrisville, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Not applicable Interventional

Effects of Femoral vs Saphenous Nerve Blocks on Function After ACL Repair

NCT01919658
View directory record Official record
Conditions
Anterior Cruciate Ligament
Interventions
nerve block
Procedure
Lead sponsor
Robert A. Gallo
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Phase 4 Interventional

Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations

NCT00314457
View directory record Official record
Conditions
ACL Repair, Meniscectomy, Bankart Repair
Interventions
Bupivacaine
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
11 Years to 19 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2009 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Phase 3 Interventional

Neocartilage Implant to Treat Cartilage Lesions of the Knee

NCT01400607
View directory record Official record
Conditions
Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
Interventions
Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
Biological · Other
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
9
States / cities
Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Jul 22, 2026, 10:40 AM EDT
Not listed No phase listed Observational

DeNovo NT Longitudinal Data Collection (LDC) Knee Study

NCT01329445
View directory record Official record
Conditions
Degenerative Lesion of Articular Cartilage of Knee, Osteochondritis Dissecans
Interventions
DeNovo NT, Natural Tissue Graft
Other
Lead sponsor
Zimmer Orthobiologics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
15
States / cities
Huntsville, Alabama • San Diego, California • Aurora, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Results available

Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study

NCT03578237
View directory record Official record
Conditions
Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee, Lower Limb Amputation Above Knee, Knee Arthropathy, Shoulder Arthroplasty, Rotator Cuff Repair, Video-Assisted Thoracoscopic Surgery (VATS), Skin Grafting
Interventions
Cryoneurolysis (active), Sham cryoneurolysis procedure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Not yet recruiting Phase 3 Interventional

PO Methadone Ortho Outpatient

NCT06351215
View directory record Official record
Conditions
Arthroscopic Knee Repair, Arthroscopic Hip Repair
Interventions
Methadone group, Placebo
Drug
Lead sponsor
Keck School of Medicine of USC
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional

Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair

NCT05494073
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear
Interventions
ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
13 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty

NCT02460172
View directory record Official record
Conditions
Arthroplasty, Knee Replacement, Wound Healing
Interventions
Zip Surgical Skin Closure, Steel Staples
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meniscal Root Tears: Evaluation Using an Ultrahigh MRI

NCT05088525
View directory record Official record
Conditions
Knee Injuries
Interventions
MRI
Procedure
Lead sponsor
Twin Cities Orthopedics
Other
Eligibility
14 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Phase 3 Interventional Results available

Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.

NCT00793104
View directory record Official record
Conditions
Knee Injury
Interventions
Placement of allograft CR Plug in primary injury site
Procedure
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
Los Angeles, California • Denver, Colorado • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 24, 2013 · Synced Jul 22, 2026, 10:40 AM EDT
Completed No phase listed Observational

Pilot Study to Assess the Use of Spy Elite for Assessment of Amputation Healing

NCT02440295
View directory record Official record
Conditions
Wound Healing, Lower Extremity Amputation, Above Knee Amputation, Below Knee Amputation
Interventions
Lower Extremity Amputation, SPY Elite Imaging System, Indocyaine Green
Procedure · Device · Drug
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Terminated Not applicable Interventional

Cartilage Autograft Implantation System (CAIS) for the Repair of Knee Cartilage Through Cartilage Regeneration

NCT00881023
View directory record Official record
Conditions
Defect of Articular Cartilage, Osteochondritis Dissecans
Interventions
Microfracture, Cartilage Autograft Implantation System
Procedure · Device
Lead sponsor
DePuy Mitek
Industry
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
27
States / cities
Tucson, Arizona • Bentonville, Arkansas • Encinitas, California + 24 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Jul 22, 2026, 10:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs

NCT03097744
View directory record Official record
Conditions
Knee Medial Meniscus Tears, Meniscus Lesion, Meniscus; Rupture, Bucket Handle, Meniscus Disorder
Interventions
Ceterix NovoStitch
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Bentonville, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2020 · Synced Jul 22, 2026, 10:40 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

NCT05074212
View directory record Official record
Conditions
Wound Heal, Wound of Skin
Interventions
Factorial Assignment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Micro-Doppler Radar: A Gold Standard Comparison

NCT05521126
View directory record Official record
Conditions
Musculoskeletal Injury, Anterior Cruciate Ligament Injuries
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Annville, Pennsylvania • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Wound Healing in Primary TKA

NCT06007599
View directory record Official record
Conditions
Total Knee Replacement, Wound Complication
Interventions
Skin closure using skin adhesive, Skin closure without skin adhesive
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional

Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial

NCT04039971
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
Interventions
ACL Reconstruction
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 19 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 10:40 AM EDT
Active, not recruiting Not applicable Interventional

Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

NCT02292004
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
Interventions
ACL Repair with MIACH Scaffold, Standard ACL Reconstruction
Device · Procedure
Lead sponsor
Miach Orthopaedics
Industry
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 10:40 AM EDT