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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:38 AM EDT

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Showing 265–288 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Completed Not applicable Interventional Results available

Combination Gel and Vascular ND in Mild to Moderate Rosacea

NCT01631656
View directory record Official record
Conditions
Rosacea
Interventions
Azelaic acid, Nd:Yag laser
Drug · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Not applicable Interventional

Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery

NCT00422045
View directory record Official record
Conditions
Surgery
Interventions
Low Level Laser Therapy
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Hyperopia Correction Using the NTK Optimal Keratoplasty (Opti-K) System

NCT01028937
View directory record Official record
Conditions
Hyperopia
Interventions
Optimal Keratoplasty
Device
Lead sponsor
NTK Enterprises, Inc.
Industry
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion

NCT01484730
View directory record Official record
Conditions
Abnormal Vascular Flow
Interventions
Multi-Spectral and Laser Speckle Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery

NCT02900794
View directory record Official record
Conditions
Sinusitis
Interventions
Gold Laser, Microdebridement
Device · Procedure
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 3 Interventional

SOLX Titanium Sapphire Laser for Trabeculoplasty

NCT00145535
View directory record Official record
Conditions
Glaucoma, Glaucoma, Open Angle
Interventions
SOLX Titanium Sapphire Laser (TiSaLT), Argon Laser Trabeculoplasty (ALT)
Device
Lead sponsor
SOLX, Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
5
States / cities
Petaluma, California • Tampa, Florida • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2010 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis

NCT06656325
View directory record Official record
Conditions
Periodontal Diseases, Periodontitis, Gum Disease
Interventions
Erchonia® FX405, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Thousand Oaks, California • Acton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting No phase listed Observational

Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

NCT01166893
View directory record Official record
Conditions
Skin Burn Multiple
Interventions
Modulated Imaging and Laser Speckle Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Minute and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn No phase listed Observational

Effect of Laser Treatment on Capillary Malformations

NCT02035319
View directory record Official record
Conditions
Capillary Malformation, Port Wine Stain
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Oct 21, 2026, 5:38 AM EDT
Not yet recruiting No phase listed Observational

Evaluating Laser Otoscope for Middle Ear Effusion Detection

NCT07454512
View directory record Official record
Conditions
Middle Ear Effusion, Otitis Media
Interventions
Laser otoscope examination
Device
Lead sponsor
MSTATT LLC
Industry
Eligibility
6 Months to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)

NCT04563039
View directory record Official record
Conditions
Urinary Stones
Interventions
Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
Device
Lead sponsor
Avvio Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
23
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Not applicable Interventional

Study to Evaluate the Safety and Performance of Spectranetics Laser w/Adjunct PTA and Gore Viabahn Endoprosthesis for Treatment of SFA Instent Restenosis

NCT00712257
View directory record Official record
Conditions
Restenosis
Interventions
Spectranetics Laser with adjunct PTA and Gore VIABAHN Endoprosthesis with Heparin Bioactive Surface
Device
Lead sponsor
VIVA Physicians
Other
Eligibility
18 Years to 89 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Early Feasibility Study of UV-Femtosecond Laser Assisted Lenticular Extraction

NCT03021707
View directory record Official record
Conditions
Refractive Error - Myopia Severe, Refractive Error - Myopia Simple
Interventions
WaveLight® Ultraviolet Femtosecond (FS) Laser System, Laser Assisted Lenticular Extraction
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Sioux Falls, South Dakota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Phase 4 Interventional

Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy

NCT04075136
View directory record Official record
Conditions
Exudative Age Related Macular Degeneration
Interventions
Ranibizumab, Photodynamic laser treatment (PDT), Triamcinolone Acetonide, verteporfin
Drug · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

NCT06721975
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
Thulio pulsed Thulium:YAG (p-Tm:YAG), Thulium Laser Fiber (TFL)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Triamcinolone vs. Laser for Diabetic Macular Edema

NCT00229931
View directory record Official record
Conditions
DIABETIC MACULAR EDEMA
Interventions
Triamcinolone acetonide, laser
Drug · Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

NCT07408154
View directory record Official record
Conditions
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Interventions
Direct Selective laser Trabeculoplasty
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma

NCT05656833
View directory record Official record
Conditions
Melasma
Interventions
Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine
Device · Other
Lead sponsor
UnionDerm
Other
Eligibility
18 Years to 74 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction

NCT04012814
View directory record Official record
Conditions
Adipose Tissue Atrophy
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Altos, California • Sacramento, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Not applicable Interventional Results available

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

NCT02881047
View directory record Official record
Conditions
Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions
CO2 Laser, Ultrasound, Skin Biopsy
Device · Radiation · Diagnostic Test
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Treatment of Surgical Scars With Fractional Photothemolysis Versus Pulse Dye Laser

NCT00685243
View directory record Official record
Conditions
Post Surgical Scars
Interventions
Laser treatment
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)

NCT02959307
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Transcranial Light Therapy, Sham Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided PRK vs Wavefront-optimized PRK

NCT02091934
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavefront-guided PRK, Wavefront-optimized PRK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of LLLT/Music for Smoking Cessation

NCT04830384
View directory record Official record
Conditions
Nicotine Dependence, Cigarettes
Interventions
Fully Active, LLLT Only, Music Only, Placebo
Device
Lead sponsor
Freedom Laser, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Mendham, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 21, 2026, 5:38 AM EDT