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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Completed No phase listed Observational Results available

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

NCT02392078
View directory record Official record
Conditions
Metastatic Brain Tumor, Primary Brain Tumor, Epileptic/Seizure Foci, Movement Disorders
Interventions
NeuroBlate System
Device
Lead sponsor
Monteris Medical
Industry
Eligibility
Not listed
Enrollment
1,153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
26
States / cities
Phoenix, Arizona • Little Rock, Arkansas • La Jolla, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Phase 1 Interventional

Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System

NCT00026871
View directory record Official record
Conditions
Neoplasm
Interventions
Radiotherapy
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Results available

Comparison of Electrodessication, Potassium Titanyl Phosphate (KTP) Laser and Pulsed Dye Laser for Treatment of Cherry Angiomata

NCT00791908
View directory record Official record
Conditions
Cherry Angioma
Interventions
Electrodessication, Pulsed dye laser (PDL), potassium titanyl phosphate (KTP)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 23, 2026, 2:23 AM EDT
Completed No phase listed Observational

Laser Ablation in Stereotactic Neurosurgery (LAISE): NeuroBlate® Retrospective Registry

NCT02389855
View directory record Official record
Conditions
Primary Brain Tumor
Interventions
NeuroBlate® System Therapy
Procedure
Lead sponsor
Monteris Medical
Industry
Eligibility
Not listed
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
9
States / cities
New Haven, Connecticut • Kansas City, Kansas • Kansas City, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction

NCT04012814
View directory record Official record
Conditions
Adipose Tissue Atrophy
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Altos, California • Sacramento, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Results available

A Device Study for the Treatment of Acne

NCT04695691
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Cutera Laser System
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
16 Years to 60 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
7
States / cities
Brisbane, California • Danville, California • Fremont, California + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 23, 2026, 2:23 AM EDT
Terminated Not applicable Interventional Results available

Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy

NCT03075176
View directory record Official record
Conditions
Surgery, Myopia
Interventions
Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK, Topography-guided Photorefractive Keratectomy
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Results available

Laser Removal of Age (Sun) Spots on Hands

NCT01885871
View directory record Official record
Conditions
Solar Lentigines
Interventions
Picosecond QS Nd:YAG Laser
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Oct 23, 2026, 2:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction

NCT02600104
View directory record Official record
Conditions
Unwanted Wrinkles
Interventions
PicoWayTM
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
4
States / cities
Chicago, Illinois • New York, New York • Ardmore, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 23, 2026, 2:23 AM EDT
Recruiting No phase listed Observational

Clinical Evaluation of WaveLight Plus LASIK

NCT07127757
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavelight Plus LASIK
Device
Lead sponsor
Laser Defined Vision
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment

NCT02700204
View directory record Official record
Conditions
Dyschromia
Interventions
PicoWay 532nm fractional treatment, PicoWay 1064nm fractional treatment
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2016 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Results available

Pediatric Laser Acupuncture and Renal Biopsy

NCT01879826
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Aculaser applied to kidney points, Aculaser applied to sham points
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Results available

Low-Level Laser in Head and Neck Chronic Lymphedema

NCT04482855
View directory record Official record
Conditions
Head and Neck Cancer, Lymphedema, Fibrosis
Interventions
Low-level laser
Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 23, 2026, 2:23 AM EDT
Active, not recruiting No phase listed Observational

Phase II Laser Focal Therapy of Prostate Cancer

NCT02243033
View directory record Official record
Conditions
Prostate Cancer
Interventions
MR-guided laser focal therapy
Device
Lead sponsor
HALO Diagnostics
Industry
Eligibility
45 Years to 90 Years · Male only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2036
U.S. locations
1
States / cities
Indian Wells, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Trio Laser Module for Hair Removal Treatment

NCT04599751
View directory record Official record
Conditions
Hair Removal Treatment
Interventions
Hair removal treatment
Device
Lead sponsor
Alma Lasers
Industry
Eligibility
18 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Hollywood, Florida • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Phase 4 Interventional Results available

Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation

NCT04187053
View directory record Official record
Conditions
DENT IMPLANTS, LASER
Interventions
Conventional mechanical therapy, Saline, Methylene Blue, Light emitting laser, Non-light emitting laser
Procedure · Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Phase 3 Interventional Results available

Laser-Ranibizumab-Triamcinolone for Proliferative Diabetic Retinopathy

NCT00445003
View directory record Official record
Conditions
Proliferative Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Ranibizumab, Triamcinolone Acetonide, Sham injection, Focal/grid laser
Drug · Behavioral · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
56
States / cities
Artesia, California • Beverly Hills, California • Irvine, California + 46 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2016 · Synced Oct 23, 2026, 2:23 AM EDT
Not listed Phase 4 Interventional

Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL

NCT04863742
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Drug
Lead sponsor
Sight Medical Doctors PLLC
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Brentwood, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 23, 2026, 2:23 AM EDT
Active, not recruiting Not applicable Interventional

Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

NCT06179654
View directory record Official record
Conditions
Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention, Lower Urinary Tract Symptoms
Interventions
Preoperative pelvic floor physical therapy
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries

NCT05284240
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Auryon Laser System
Device
Lead sponsor
Midwest Cardiovascular Research Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Miami Beach, Florida • Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Randomized, Controlled Trial With Hybrid Fractional Laser

NCT03647189
View directory record Official record
Conditions
Vaginal Atrophy, Sexual Dysfunction, Vaginal Dryness, Dyspareunia
Interventions
Hybrid Fractional Laser
Device
Lead sponsor
Sciton
Industry
Eligibility
40 Years to 70 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes

NCT04126174
View directory record Official record
Conditions
Cataract
Interventions
femtosecond laser system arcuate corneal incision, Manual LRI
Device · Other
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
40 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 23, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women

NCT05336825
View directory record Official record
Conditions
Vulvodynia
Interventions
CO2 laser, Lidocaine patch 5%
Device · Drug
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Denville, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 23, 2026, 2:23 AM EDT
Active, not recruiting Not applicable Interventional

LLLT to Reduce Low Back Pain

NCT06007976
View directory record Official record
Conditions
Low Back Pain
Interventions
Erchonia® Trident
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 23, 2026, 2:23 AM EDT