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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Labour Pain Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Management of Postoperative Pain With Preemptive Analgesia in Cesarean Section

NCT02879435
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine, Placebo
Drug · Other
Lead sponsor
Mark Kosanovich
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 4 Interventional Results available

Comparing Effectiveness of CSE Versus DPE for Labor Analgesia

NCT05068661
View directory record Official record
Conditions
Labor Pain
Interventions
Ropivacaine 0.1% Injectable Solution, Bupivacaine 0.25% Injectable Solution
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Sep 20, 2026, 11:27 AM EDT
Terminated Phase 4 Interventional Results available

Drug Concentration and Volume on Adequate Labor Analgesia With PIEB

NCT03553576
View directory record Official record
Conditions
Pain, Anesthesia, Labor Pain
Interventions
Low volume bolus, High volume bolus
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 20, 2026, 11:27 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia

NCT05543694
View directory record Official record
Conditions
Labor Pain, Analgesia
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional Results available

Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40

NCT02984267
View directory record Official record
Conditions
Labor Pain
Interventions
Ultrasound, Palpation
Device · Other
Lead sponsor
Thomas J. Vernon
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Pain Relief Effects on Length of Labor

NCT01750099
View directory record Official record
Conditions
Labor Pain
Interventions
Combined Spinal-epidural, Continuous Lumbar epidural
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2014 · Synced Sep 20, 2026, 11:27 AM EDT
Recruiting No phase listed Observational

Dural Puncture Epidural (DPE) Technique: Efficacy and Safety Overview.

NCT07704554
View directory record Official record
Conditions
Labor Pain
Interventions
Dural Puncture Epidural (DPE) Technique
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional Results available

DilaCheck Cervical Dilation Measurement Trial

NCT03440723
View directory record Official record
Conditions
Cervical Dilation, Labor Pain, Labor Fast, Labor; Irregular
Interventions
DilaCheck, Cervical dilation examination
Device · Diagnostic Test
Lead sponsor
Elm Tree Medical Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery

NCT05498025
View directory record Official record
Conditions
Pain, Acute, Opioid Misuse, Obstetric Pain, Cesarean Section Complications
Interventions
Deterra activated charcoal pouch
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses

NCT02340806
View directory record Official record
Conditions
Labor Pain, Obstetric Pain
Interventions
CADD-Solis pump (Smiths Medical)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fetal Life: Smart-Device Based Uterine Activity Monitoring

NCT03940365
View directory record Official record
Conditions
Labor Pain, Contraction
Interventions
Fetal Life tocometer device
Device
Lead sponsor
Fetal Life LLC
Industry
Eligibility
20 Years to 40 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Lidocaine Patches After Cesarean Section

NCT04443569
View directory record Official record
Conditions
Postoperative Pain, Obstetric Pain, Opioid Use
Interventions
Lidocaine patch, Placebo patch
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 52 Years · Female only
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation

NCT03103100
View directory record Official record
Conditions
Labor Pain
Interventions
1% Lidocaine, 0.25% Bupivacaine, Bupivacaine plus Lidocaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Sep 20, 2026, 11:27 AM EDT
Not listed No phase listed Observational

Pulsed Heat as a Drug-free Treatment for Pregnancy Related Pain

NCT05628298
View directory record Official record
Conditions
Pain, Pain, Labor
Interventions
Soovu Pain Relief System
Device
Lead sponsor
Soovu Labs Inc.
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
35 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 27, 2022 · Synced Sep 20, 2026, 11:27 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality in Labor and Delivery for Reduction in Pain

NCT03437031
View directory record Official record
Conditions
Labor Pain, Virtual Reality, Alternative Medicine
Interventions
Virtual Reality device
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Sep 20, 2026, 11:27 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Genetic and Demographic Factors That Influence the Pain and Progress of Labor

NCT02178878
View directory record Official record
Conditions
Rapid Progress of Labor
Interventions
Progress, Pain
Genetic
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Sep 20, 2026, 11:27 AM EDT
Completed No phase listed Observational

Color Doppler Ultrasound to Locate Needle in Labor Epidural

NCT03596333
View directory record Official record
Conditions
Labor Pain, Obstetric Pain
Interventions
Retrospective chart review
Other
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Combined Spinal-Epidural Versus Traditional Labor Epidural

NCT00151346
View directory record Official record
Conditions
Labour Pain
Interventions
Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2008 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Not applicable Interventional

The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia

NCT02672397
View directory record Official record
Conditions
Labor Pain
Interventions
Additional Epidural Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)

NCT02105558
View directory record Official record
Conditions
Labor Pain, Complications; Cesarean Section, Pregnancy
Interventions
Epidural anesthesia, Combined spinal and epidural anesthesia
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Sep 20, 2026, 11:27 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

NCT02121184
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Routine oxytocin, Half-dose oxytocin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 20, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Intrathecal Hydromorphone for Labor Analgesia

NCT01598506
View directory record Official record
Conditions
Labor Pain
Interventions
Hydromorphone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Sep 20, 2026, 11:27 AM EDT
Not listed Phase 4 Interventional

Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement

NCT01651962
View directory record Official record
Conditions
Labor Pain
Interventions
Terbutaline, Fentanyl, 0.9% NaCl
Drug
Lead sponsor
Kai Schoenhage
Other
Eligibility
18 Years to 53 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 20, 2026, 11:27 AM EDT
Withdrawn Phase 4 Interventional

Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor

NCT00691795
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine or fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Sep 20, 2026, 11:27 AM EDT