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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Late Effect Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Emotional and Cognitive Control in Late-Onset Depression

NCT01728194
View directory record Official record
Conditions
Depression
Interventions
Escitalopram, Magnetic Resonance Imaging
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 85 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Jul 24, 2026, 5:50 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID

NCT06161688
View directory record Official record
Conditions
Long COVID, Post Acute Sequelae of COVID-19, Post-Acute COVID-19
Interventions
Ensitrelvir, Placebo
Drug · Other
Lead sponsor
Timothy Henrich
Other
Eligibility
18 Years to 69 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury

NCT00830453
View directory record Official record
Conditions
Brain Injury, Sequelae, Stroke, Anoxia, Trauma
Interventions
Hyperbaric oxygen therapy (HBO2)
Procedure
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 14, 2021 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Late Dinner on Nocturnal Metabolism

NCT03525717
View directory record Official record
Conditions
Healthy
Interventions
Routine Dinner, Late dinner
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 30 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

eHealth Insomnia Intervention for Adult Survivors of Childhood Cancer

NCT04317742
View directory record Official record
Conditions
Childhood Cancer, Insomnia, Neurocognitive Impairment, Survivorship, Late Effect, Sleep
Interventions
Sleep Healthy Using the Internet (SHUTi) Intervention Group, Online Patient Education (PE) Control Group
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
1,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TaiChi-DTx for Treating Long Covid Symptoms

NCT05419219
View directory record Official record
Conditions
Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
Interventions
the multi-domain Tai Chi Digital therapy Software Application
Device
Lead sponsor
Tim Shi
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ellicott City, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Jul 24, 2026, 5:50 AM EDT
Completed No phase listed Observational

Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors

NCT00664131
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Neurological Examination/Questionnaires
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
6 Years to 28 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 22, 2011 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109

NCT01640912
View directory record Official record
Conditions
Cicatrix, Scar Prevention
Interventions
RXI-109, Placebo
Drug
Lead sponsor
RXi Pharmaceuticals, Corp.
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Jul 24, 2026, 5:50 AM EDT
Completed No phase listed Observational

Childhood Cancer Survivors' Knowledge of Diagnosis,Treatment and Risk of Late Effects: Specialized Survivorship Clinic

NCT01223872
View directory record Official record
Conditions
Childhood Cancer
Interventions
interview, clinic visit and interview, interviews and clinic visit
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 21 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Jul 24, 2026, 5:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Early and Late Time-Restricted Feeding on Body Composition

NCT04000516
View directory record Official record
Conditions
Time Restricted Feeding
Interventions
Time restricted feeding
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
19 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Jul 24, 2026, 5:50 AM EDT
Recruiting Phase 3 Interventional

Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

NCT06960928
View directory record Official record
Conditions
Long COVID-19
Interventions
Low-dose sirolimus, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Active, not recruiting Phase 2 Interventional

Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction

NCT06204432
View directory record Official record
Conditions
Long Haul COVID-19, Post-Acute COVID-19 Syndrome, Anosmia, Olfaction Disorders
Interventions
Sodium Citrate, Normal Saline, Olfactory Training Kit - "The Olfactory Kit, by AdvancedRx"
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Jul 24, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2

NCT07278388
View directory record Official record
Conditions
PASC Post Acute Sequelae of COVID 19, Fatigue
Interventions
Physical Fatigue
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Long COVID Ultrasound Trial

NCT06189066
View directory record Official record
Conditions
Long Covid
Interventions
Splenic Ultrasound
Device
Lead sponsor
SecondWave Systems Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Phase 1 Interventional Results available

Accelerated rTMS for Post-Stroke Apathy

NCT05878457
View directory record Official record
Conditions
Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack, Motivation, Abulia
Interventions
MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications

NCT03773575
View directory record Official record
Conditions
Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma, Wound Infection, Surgical, Lymph Leakage
Interventions
PREVENA™ PEEL & PLACE™ Dressing Kit
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Valhalla, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Phase 2 Interventional

Do Endotypes Predict Response and Sequelae in OSA Patients

NCT04875364
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep Apnea, Obstructive, Sleep, Sleep Disorder
Interventions
Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP)
Drug · Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Active, not recruiting Phase 2 Interventional

AT1001 for the Treatment of Long COVID

NCT05747534
View directory record Official record
Conditions
Long COVID, Long COVID-19, Post Acute COVID-19 Syndrome, Post Acute Sequelae of COVID-19
Interventions
Larazotide Acetate, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
7 Years to 50 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Completed No phase listed Observational

Late Effects of Treatment for Sarcomas in Children

NCT00006515
View directory record Official record
Conditions
Sarcoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
7 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 24, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Effects of Aerobic Exercise for Treating Alzheimer's Disease

NCT01954550
View directory record Official record
Conditions
Alzheimer's Disease, Late Onset
Interventions
Cycling exercise, Range of motion/stretching exercise
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
66 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Jul 24, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Care for Veterans Post-COVID-19

NCT05787379
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome
Interventions
Concordant Care Training, Education Packet Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 24, 2026, 5:50 AM EDT
Enrolling by invitation Phase 2 Interventional

DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury

NCT07567274
View directory record Official record
Conditions
Tinnitus
Interventions
DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine
Drug
Lead sponsor
Leading Edge Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Jul 24, 2026, 5:50 AM EDT
Recruiting Phase 2 Interventional

Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

NCT05626894
View directory record Official record
Conditions
Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
Interventions
StrokeWear Motor and Behavioral Intervention, Usual Care
Combination Product · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 24, 2026, 5:50 AM EDT